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Do Heart Failure Biomarkers Influence Heart Failure Treatment Response?
Purpose of ReviewHeart failure (HF) is one of the leading causes of cardiac morbidity and mortality around the world. Our evolving understanding of...
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Identification and verification of inflammatory biomarkers for primary Sjögren’s syndrome
IntroductionPrimary Sjögren’s syndrome (pSS) is an autoimmune disease characterized by inflammatory infiltration, and dysfunction of the salivary and...
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Associations of liver function with plasma biomarkers for Alzheimer’s Disease
BackgroundBlood-based biomarkers for Alzheimer’s disease (AD) are promising to be used in clinical settings. The liver is an important degradation...
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Predictive biomarkers for immunotherapy response in extensive-stage SCLC
BackgroundSmall cell lung cancer (SCLC) accounts for about 13–15% of all lung cancers, and about 70% of SCLC patients have developed extensive-stage...
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Quantitative PET-based biomarkers in lymphoma: getting ready for primetime
The use of functional quantitative biomarkers extracted from routine PET–CT scans to characterize clinical responses in patients with lymphoma is...
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Biomarkers of Autoimmune Chronic Spontaneous Urticaria
Purposeof ReviewChronic spontaneous urticaria and chronic inducible urticaria (CSU/CindU) are caused by mast cell and basophil activation leading to...
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Biomarkers and Cognition Study, Singapore (BIOCIS): Protocol, Study Design, and Preliminary Findings
BackgroundThe focus of medicine is shifting from treatment to preventive care. The expression of biomarkers of dementia and Alzheimer’s disease (AD)...
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The Critical Role of Biomarkers for Drug Development Targeting the Biology of Aging
Alzheimer’s disease is a devastating neurodegenerative disorder that poses a significant societal burden. Approval of anti-amyloid antibody therapies...
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Biomarkers of sarcopenia: an unmet need
BackgroundSarcopenia is a syndrome characterized by a progressive decline in muscle mass and strength, with subsequent deterioration of functional...
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Agreement of cerebrospinal fluid biomarkers and amyloid-PET in a multicenter study
Core Alzheimer’s disease (AD) cerebrospinal fluid (CSF) biomarkers have shown incomplete agreement with amyloid-positron emission tomography (PET)....
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Biomarkers of cellular senescence in idiopathic pulmonary fibrosis
BackgroundCellular senescence is a cell fate in response to diverse forms of age-related damage and stress that has been implicated in the...
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Biomarkers in amyotrophic lateral sclerosis: current status and future prospects
Disease heterogeneity in amyotrophic lateral sclerosis poses a substantial challenge in drug development. Categorization based on clinical features...
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Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors
BackgroundThe emerging use of biomarkers in research and tailored care introduces a need for information about the association between biomarkers and...
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Sex-based Differences in Heart Failure Biomarkers
Purpose of ReviewDifferences in HF biomarker levels by sex may be due to hormonal, genetic, and fat distribution differences. Knowledge of these...
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Retinal OCT biomarkers and their association with cognitive function—clinical and AI approaches
Retinal optical coherence tomography (OCT) biomarkers have the potential to serve as early, noninvasive, and cost-effective markers for identifying...
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Diagnostic and progression biomarkers in cerebrospinal fluid of Alzheimer’s disease patients
In this commentary, we address a paper published by Johnson et al. by assessing the robustness of their method to discover diagnostic biomarkers in...
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Biomarkers for the Progression of Intermediate Age-Related Macular Degeneration
Age-related macular degeneration (AMD) is a leading cause of severe vision loss worldwide, with a global prevalence that is predicted to...
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Unlocking the power of precision medicine: exploring the role of biomarkers in cancer management
BackgroundPersonalized or Precision medicine (PM) is a promising approach for the cancer treatment that tailors treatment to a patient's...
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Plasma biomarkers for prediction of Alzheimer’s disease neuropathologic change
While plasma biomarkers for Alzheimer’s disease (AD) are increasingly being evaluated for clinical diagnosis and prognosis, few population-based...
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Biomarkers of Bipolar Disorder in Late Life: An Evidence-Based Systematic Review
Purpose of ReviewReview the current evidence on biomarkers for bipolar disorder in the older adults. We conducted a systematic search of PubMed...