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Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial (BICS)
BackgroundChronic obstructive pulmonary disease (COPD) is associated with significant morbidity, mortality and healthcare costs. Beta blockers are...
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Beta-blocker therapy in patients with COPD: a systematic literature review and meta-analysis with multiple treatment comparison
BackgroundBeta-blockers are associated with reduced mortality in patients with cardiovascular disease but are often under prescribed in those with...
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Post-diagnostic beta blocker use and breast cancer-specific mortality: a population-based cohort study
PurposeBeta blockers (BB) have been associated with improved, worsened, or unchanged breast cancer outcomes in previous studies. This study examines...
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Implications of Under-Reporting Medication Side Effects: Beta-Blockers in Heart Failure as a Case Example
IntroductionPerceiving medication side effects but not reporting them to a clinician is common. Patterns of “under-reporting” and their implications...
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Efficacy and safety of intravenous beta-blockers in acute atrial fibrillation and flutter is dependent on beta-1 selectivity: a systematic review and meta-analysis of randomised trials
BackgroundIntravenous beta-blockers are commonly used to manage patients with acute atrial fibrillation (AF) and atrial flutter (AFl), but the choice...
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Evaluating Provider and Pharmacy Discordance in Potential Calcium Channel Blocker–Loop Diuretic Prescribing Cascade
BackgroundPrescribing cascades occur when a drug-induced adverse event is treated with a new medication. Identifying clinical scenarios in which...
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Beta-adrenergic blocker inhibits oral carcinogenesis and reduces tumor invasion
PurposeBeta-adrenergic signaling can influence cancer progression and the use of beta blockers as adjuvant drugs in oncologic patients has been...
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Successful treatment of severe adrenaline-resistant anaphylactic shock with glucagon in a patient taking a beta-blocker: a case report
BackgroundThe efficacy of glucagon for adrenaline-resistant anaphylactic shock in patients taking β-blockers is controversial. However, understanding...
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Beta-adrenergic receptor blockers and hepatocellular carcinoma survival: a systemic review and meta-analysis
IntroductionPreclinical data have revealed that beta-adrenergic stimulation can affect the growth and progression of different types of malignancies....
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Left atrial dysfunction can independently predict exercise capacity in patients with chronic heart failure who use beta-blockers
BackgroundBeta-blockers are first-line clinical drugs for the treatment of chronic heart failure (CHF). In the guidelines for cardiac rehabilitation,...
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Impact of baseline beta-blocker use on inotrope response and clinical outcomes in cardiogenic shock: a subgroup analysis of the DOREMI trial
BackgroundCardiogenic shock (CS) is associated with significant morbidity and mortality. The impact of beta-blocker (BB) use on patients who develop...
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Early Intravenous Beta-Blockade with Esmolol in Adults with Severe Traumatic Brain Injury: A Phase 2a Intervention Design Study
BackgroundTargeted beta-blockade after severe traumatic brain injury may reduce secondary brain injury by attenuating the sympathoadrenal response....
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Beta-Adrenergic Receptor Blockade Effects on Cardio-Pulmonary Exercise Testing in Healthy Young Adults: A Randomized, Placebo-Controlled Trial
BackgroundBeta-blockers are increasingly prescribed while the effects of beta-adrenergic receptor blockade on cardio-pulmonary exercise test...
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Beta blockers are associated with lower all-cause mortality among HFpEF patients
BackgroundThe evidence regarding beta blocker (BB) benefit in heart failure with preserved ejection fraction (HFpEF) remains inconclusive, leading to...
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Comparison of add-on medications for persistent storage symptoms after α-blocker treatment in BPH patients – a network meta-analysis
BackgroundPatients with benign prostatic hyperplasia (BPH) receive α-blockers as first-line therapy to treat lower urinary tract symptoms; however,...
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Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of oesophageal varices: study protocol for a randomised controlled trial
BackgroundLiver disease is within the top five causes of premature death in adults. Deaths caused by complications of cirrhosis continue to rise,...
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Predicting factors for omitting beta-blockers in patients with tachycardia-induced cardiomyopathy after successful catheter ablation for atrial fibrillation
Tachycardia induces a reduction in the left ventricular ejection fraction (LVEF), which is defined as tachycardia-induced cardiomyopathy (TIC)....
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Perioperative beta-blocker and its effect on coronary artery bypass graft patients outcome after surgery
BackgroundBeta-adrenergic receptor blockers have been studied for minimizing the effects of catecholamines by blocking their activation of beta...
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Effect of Clinical and Genetic Factors on the Development of Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG) in Egyptian Patients Receiving Beta-Blockers
PurposeProphylactic beta-blockers are recommended to prevent postoperative atrial fibrillation (POAF) after coronary artery bypass grafting (CABG)....
