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Systematic review of research design and reporting of imaging studies applying convolutional neural networks for radiological cancer diagnosis
ObjectivesTo perform a systematic review of design and reporting of imaging studies applying convolutional neural network models for radiological...
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Intracranial haemorrhage and falls: cause or effect?
IntroductionA difficult question in autopsy practice is whether intracranial haemorrhage has resulted from or brought about a fall.
Material and...
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European Medicines Agency Policy 0070: an exploratory review of data utility in clinical study reports for academic research
BackgroundClinical study reports (CSRs) have been increasingly utilised within academic research in recent years. European Medicines Agency (EMA)...
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Results from 237 extracorporeal membrane oxygenation runs with drowned patients: a nationwide retrospective study
BackgroundDrowning is one of the leading causes of death worldwide and presents with a wide range of symptoms, from simple coughing to cardiac or...
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Development of a diagnostic support system for distal humerus fracture using artificial intelligence
PurposeAI has shown promise in automating and improving various tasks, including medical image analysis. Distal humerus fractures are a critical...
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Assisting the implementation of screening for type 1 diabetes by using artificial intelligence on publicly available data
The type 1 diabetes community is coalescing around the benefits and advantages of early screening for disease risk. To be accepted by healthcare...
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Treatment Patterns and Pharmacoutilization in Patients Affected by Psoriasis: An Observational Study in an Italian Real-World Setting
BackgroundReal-world data can inform the use of biologics for psoriasis (PSO).
ObjectiveThe aim was to evaluate treatment patterns and analyze...
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Quality of MedDRA® Coding in a Sample of COVID-19 Vaccine Medication Error Data
IntroductionIn recent years, there has been increasing interest from regulatory agencies and scientific organisations into the recording, coding and...
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Combined conventional factors and the radiomics signature of coronary plaque texture could improve cardiac risk prediction
ObjectivesThis study aims to investigate how radiomics analysis can help understand the association between plaque texture, epicardial adipose tissue...
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NAVIGATOR: an Italian regional imaging biobank to promote precision medicine for oncologic patients
NAVIGATOR is an Italian regional project boosting precision medicine in oncology with the aim of making it more predictive, preventive, and...
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Curation of myeloma observational study MALIMAR using XNAT: solving the challenges posed by real-world data
ObjectivesMAchine Learning In MyelomA Response (MALIMAR) is an observational clinical study combining “real-world” and clinical trial data, both...
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Sharing real-world data for public benefit: a qualitative exploration of stakeholder views and perceptions
BackgroundThere has been an increasing interest in the use of “real-world” data to inform care decision making that could lead to public health...
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Development, implementation and evaluation of the digital transformation of renal services in Wales: the journey from local to national
BackgroundTreatment for people with kidney disease is often associated with complicated combinations of medicines. Logistical challenges with...
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General data protection regulations (2018) and clinical research: perspectives of patients and doctors in an Irish university teaching hospital
BackgroundEurope’s General Data Protection Regulation, or GDPR, is a set of data protection rules on the acquisition, storage, use, and access of...
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A critical appraisal of emergency resuscitative thoracotomy in a Western European level 1 trauma centre: a 13-year experience
Emergency Resuscitative Thoracotomy (ERT) is a lifesaving procedure in selected patients. Outcome mostly in blunt trauma is believed to be poor. The...
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A Delphi consensus statement for digital surgery
The use of digital technology is increasing rapidly across surgical specialities, yet there is no consensus for the term ‘digital surgery’. This is...
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Expanding citizen engagement in the secondary use of health data: an opportunity for national health data access bodies to realise the intentions of the European Health Data Space
The European Health Data Space (EHDS) aims to make the primary use of health data for healthcare provision more continuous, effective, and (cost)...
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What motivates public collaborators to become and stay involved in health research?
BackgroundPeople with lived experience of health and illness are increasingly being involved in research. Knowing what creates interest in becoming...
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Diagnostic accuracy of diastolic pressure ratio using a pressure microcatheter for intracoronary physiological assessment
Recently, instantaneous wave-free ratio (iFR) has emerged as an alternative to the fractional flow reserve (FFR) for intracoronary physiological...
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Short-term outcomes in robotic vs laparoscopic ileal pouch-anal anastomosis surgery: a propensity score match study
PurposeLaparoscopic ileal pouch-anal anastomosis (IPAA) surgery offers improved short-term outcomes over open surgery but can be technically...
