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Human Histology and Persistence of Various Injectable Filler Substances for Soft Tissue Augmentation
An increasing number of soft tissue filler substances have been introduced to the beauty market outside the U.S. which lackexperimental and clinical...
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Sarcoid-like reaction and hypothyroidism induced by PD-1 inhibitor treatment in metastatic renal cell carcinoma: a case report and literature review
BackgroundPembrolizumab is among the approved treatments for a variety of cancer types, including clear cell renal cell carcinoma (ccRCC). It has...
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Epicardial Adipose Tissue: a Potential Therapeutic Target for Cardiovascular Diseases
With increased ageing of the population, cardiovascular disease (CVD) has become the most important factor endangering human health worldwide....
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Adverse Events Associated with Hyaluronic Acid Filler Injection for Non-surgical Facial Aesthetics: A Systematic Review of High Level of Evidence Studies
BackgroundHyaluronic acid (HA) dermal fillers are widely used in aesthetic medicine. While generally safe, potential complications can arise.
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Adverse effects of tyrosine kinase inhibitors in cancer therapy: pathophysiology, mechanisms and clinical management
Since their invention in the early 2000s, tyrosine kinase inhibitors (TKIs) have gained prominence as the most effective pathway-directed anti-cancer...
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Interchangeability and adverse events in originator-rituximab and its biosimilar (CT-P10) among rheumatic patients: a real-life experience
Biosimilars offer cost-effective and safe treatment options both for patients and healthcare systems. CT-P10 is the first biosimilar of rituximab...
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N-(2,3-dihydroxypropyl) carbamoyl side chain: a potentially significant factor for recurrent iodinated contrast medium-related adverse drug reactions
PurposeTo determine whether switching to contrast media based on the sharing of N -(2,3-dihydroxypropyl) carbamoyl side chain reduces the recurrence...
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Tissue Remodeling After Implantation with Polymethylmethacrylate: An Experimental Study in Mice
Polymethylmethacrylate (PMMA) is a filler used for aesthetic and/or repair purposes. The response to the implantation of biomaterials varies...
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Adverse Reactions to Anti-Infective Vaccines: an Emerging Problem in the COVID-19 Era
Purpose of reviewVaccines are an essential tool for preventing infectious diseases and reducing associated morbidity and mortality. Vaccination has a...
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Noninfectious tissue interactions at periprosthetic interfaces
The success of hip arthroplasty is based on modern materials in addition to the continuous development of surgical techniques and clinical experience...
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Switch maintenance therapy with anlotinib after chemotherapy in unresectable or metastatic soft tissue sarcoma: a single-center retrospective study
Background Chemotherapy is an important first-line treatment option in patients with advanced soft tissue sarcoma (STS). Whether maintenance therapy...
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HLA and tumour immunology: immune escape, immunotherapy and immune-related adverse events
PurposeAs molecules responsible for presenting antigens to T lymphocytes, leukocytes antigens (HLAs) play a vital role in cancer immunology. This...
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Patterns of use and adverse events reported among persons who regularly inject buprenorphine: a systematic review
Background and AimsGiven the ongoing opioid crisis, novel interventions to treat severe opioid use disorder (OUD) are urgently needed. Injectable...
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Mitigating acute chemotherapy-associated adverse events in patients with cancer
Despite the enthusiasm surrounding novel targeted agents and immunotherapies, chemotherapy remains the mainstay treatment for most human...
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Prospects and challenges for the application of tissue engineering technologies in the treatment of bone infections
Osteomyelitis is a devastating disease caused by microbial infection in deep bone tissue. Its high recurrence rate and impaired restoration of bone...
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A case of pediatric serum sickness like reaction (SSLR) after a 2-month re-exposure to amoxicillin
BackgroundSerum-sickness like reactions (SSLRs) to amoxicillin have been documented in the medical literature. Beta-lactams are important and...
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Hedgehog signaling in tissue homeostasis, cancers, and targeted therapies
The past decade has seen significant advances in our understanding of Hedgehog (HH) signaling pathway in various biological events. HH signaling...
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The Aetiopathogenesis of Late Inflammatory Reactions (LIRs) After Soft Tissue Filler Use: A Systematic Review of the Literature
BackgroundLate inflammatory reactions (LIRs) are the most challenging complications after filler use. The immune system plays a prominent role in its...
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Correlation among post-surgery recurrence of CRSwNP and TCM syndromes and tissue inflammatory cell infiltration type: a study protocol
BackgroundFunctional endoscopic sinus surgery is a principal option for treating chronic rhinosinusitis with nasal polyps (CRSwNP) after medication...
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The use of dual mobility cups in revision total hip arthroplasty for failed large head metal-on-metal bearings
PurposeRevision of failed large head metal-on-metal (MoM) total hip arthroplasty (THA) is a challenging procedure particularly to reconstruct...
