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Post-acute sequelae of COVID-19 (PASC): a meta-narrative review of pathophysiology, prevalence, and management
Coronavirus Disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Over 220 countries and territories...
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Safety and benefits of major hepatectomy with extrahepatic bile duct resection in older perihilar cholangiocarcinoma patients
PurposeTo evaluate the safety and benefits of major hepatectomy with extrahepatic bile duct resection in older perihilar cholangiocarcinoma patients...
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The critically ill older patient with sepsis: a narrative review
Sepsis is a significant public health concern, particularly affecting individuals above 70 years in developed countries. This is a crucial fact due...
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A simple algorithm for differential diagnosis in hemodynamic shock based on left ventricle outflow tract velocity–time integral measurement: a case series
Echocardiography has gained wide acceptance among intensive care physicians during the last 15 years. The lack of accredited formation, the long...
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A multinational, phase 2, randomised, adaptive protocol to evaluate immunogenicity and reactogenicity of different COVID-19 vaccines in adults ≥75 already vaccinated against SARS-CoV-2 (EU-COVAT-1-AGED): a trial conducted within the VACCELERATE network
BackgroundIn the ongoing COVID-19 pandemic, advanced age is a risk factor for a severe clinical course of SARS-CoV-2 infection. Thus, older people...
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Italian Society of Anesthesia, Analgesia, Resuscitation, and Intensive Care expert consensus statement on the use of lung ultrasound in critically ill patients with coronavirus disease 2019 (ITACO)
BackgroundTo produce statements based on the available evidence and an expert consensus (as members of the Lung Ultrasound Working Group of the...
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How to Define and Meet Blood Pressure Targets After Traumatic Brain Injury: A Narrative Review
BackgroundTraumatic brain injury (TBI) poses a significant challenge to healthcare providers, necessitating meticulous management of hemodynamic...
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Clinical Management of Adult Coronavirus Infection Disease 2019 (COVID-19) Positive in the Setting of Low and Medium Intensity of Care: a Short Practical Review
Coronavirus disease 2019 (COVID-2019) is a viral infection which is rapidly spreading on a global scale and causing a severe acute respiratory...
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Treatment of MIS-C in Children and Adolescents
Purpose of ReviewDifferent treatment approaches have been described for the management of COVID-19-related multisystem inflammatory syndrome in...
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The importance of airway and lung microbiome in the critically ill
During critical illness, there are a multitude of forces such as antibiotic use, mechanical ventilation, diet changes and inflammatory responses that...
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Flowchart for non-invasive ventilation support in COVID-19 patients from a northern Italy Emergency Department
With the rapid pandemic spread of the novel coronavirus (SARS-CoV2), Emergency Departments of affected countries are facing an increasing number of...
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Management of Arrhythmias Associated with COVID-19
Purpose of ReviewCardiac arrhythmias are known complications in patients with COVID-19 infection that may persist even after recovery from infection....
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A proposed lung ultrasound and phenotypic algorithm for the care of COVID-19 patients with acute respiratory failure
Pulmonary complications are the most common clinical manifestations of coronavirus disease (COVID-19). From recent clinical observation, two...
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SARS-CoV-2 infection in a patient with propionic acidemia
We describe a 14-month-old boy, with a previous diagnosis of propionic acidemia (PA) by expanded newborn screening, who, admitted for a suspected...
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Safety profile of enhanced thromboprophylaxis strategies for critically ill COVID-19 patients during the first wave of the pandemic: observational report from 28 European intensive care units
IntroductionCritical illness from SARS-CoV-2 infection (COVID-19) is associated with a high burden of pulmonary embolism (PE) and thromboembolic...
