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Ras protein abundance correlates with Ras isoform mutation patterns in cancer
Activating mutations of Ras genes are often observed in cancer. The protein products of the three Ras genes are almost identical. However, for...
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Sequential RAS mutations evaluation in cell-free DNA of patients with tissue RAS wild-type metastatic colorectal cancer: the PERSEIDA (Cohort 2) study
PurposeRAS ( KRAS / NRAS ) mutational status on a tumor biopsy is mandatory to guide the best treatment in metastatic colorectal cancer (mCRC)....
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Origin and Evolution of RAS Membrane Targeting
KRAS , HRAS and NRAS proto-oncogenes belong to a family of 40 highly homologous genes, which in turn are a subset of a superfamily of >160 genes...
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Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells
-7/del(7q) is prevalent across subtypes of myeloid neoplasms. CUX1 , located on 7q22, encodes a homeodomain-containing transcription factor, and, like...
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Current urological applications of the Hugo™ RAS system
PurposeTo provide an update on the diverse, contemporary urological applications of the Hugo™ RAS system.
MethodsA comprehensive literature review...
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RAS-Mutant Follicular Thyroid Tumors: A Continuous Challenge for Pathologists
The classification of thyroid nodules, particularly those with a follicular growth pattern, has significantly evolved. These tumors, enriched with RAS ...
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Robotic transversus abdominis release using HUGO RAS system: our initial experience
BackgroundTransversus abdominis release (TAR) is an effective technique for treating large midline and off-midline hernias. Recent studies have...
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Status of robotic assisted surgery (RAS) and the effects of Coronavirus (COVID-19) on RAS in the Department of Defense (DoD)
The purpose of this study is to update the available literature with information on the current use of robotic assisted surgery (RAS) in the...
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Unraveling the Genetic Web: H-Ras Expression and Mutation in Oral Squamous Cell Carcinoma—A Systematic Review
BackgroundOral squamous cell carcinoma (OSCC) is a commonly occurring malignancy with complex genetic alterations contributing to its development....
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Prenatal LPS leads to increases in RAS expression within the PVN and overactivation of sympathetic outflow in offspring rats
The renin-angiotensin system (RAS) and the sympathetic nervous system (SNS) are two major blood pressure-regulating systems. The link between the...
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Staff perceptions of factors affecting the use of RAS-DS to support collaborative mental health practice
BackgroundThe Recovery Assessment Scale: Domains and Stages (RAS-DS) was designed to be both a recovery outcome measure and a tool to enhance...
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Perception of robotic-assisted surgery (RAS) among medical students: a systematic review and meta-analysis
IntroductionRobotic surgery, also known as robotic-assisted surgery (RAS), involves a camera and a small surgical instrument attached to a robotic...
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Robotic Heller’s myotomy using the new Hugo™ RAS system: first worldwide report
BackgroundAchalasia is a rare disorder of the esophagus characterized by motor dysfunction in the esophagus and relaxation failure of the lower...
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A computational approach to assessing the prognostic implications of BRAF and RAS mutations in patients with papillary thyroid carcinoma
Papillary thyroid carcinoma (PTC) is the most common thyroid cancer, posing a growing clinical challenge. PTC exhibits two age-related peaks, with...
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Temporal dynamics of RAS mutations in circulating tumor DNA in metastatic colorectal cancer: clinical significance of mutation loss during treatment
PurposeIn metastatic colorectal cancer (mCRC), RAS mutation loss may occur during the standard-of-care regimen. In this study, we aimed to...
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New Developments in Treating RAS-Mutated Metastatic Colorectal Cancer
One of the great challenges in digestive oncology is choosing the optimal therapy for RAS -mutated metastatic colorectal cancer (mCRC). Even though...
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How experienced robotic nurses adapt to the Hugo™ RAS system
No studies have reported on the impact at team level of the Medtronic Hugo ™ RAS system. We described the work patterns and learning curves of an...
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Cell-free circulating RAS mutation concentrations significantly impact the survival of metastatic colorectal cancer patients
PurposeRAS mutations are predictors of an adverse outcome in EGFR-targeted therapies and have been proposed as prognostic biomarkers of survival in...
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First report of robotic-assisted total hysterectomy using the Hugo™ RAS system
This study describes the first reported treatment of a benign gynecological disease with the Medtronic’s Hugo™ RAS System, the first robot-assisted...
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Machine learning-based radiomics analysis in predicting RAS mutational status using magnetic resonance imaging
PurposeTo assess the efficacy of radiomics features, obtained by magnetic resonance imaging (MRI) with hepatospecific contrast agent, in pre-surgical...
