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Epidemiology, antifungal susceptibility, risk factors, and mortality of persistent candidemia in adult patients in China: a 6-year multicenter retrospective study
BackgroundData on persistent candidemia (PC), a recognized complication of candidemia, are lacking in China. This study aimed to investigate the...
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Candidemia in patients with head and neck cancer: mortality and a novel risk factor
PurposeCandidemia is a bloodstream infection (BSI) by Candida spp. and is associated with high mortality. However, there have been few reports about...
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Factors associated with the development of ocular candidiasis and ocular prognosis with echinocandin therapy for candidemia
PurposeTo evaluate the factors associated with the development of ocular candidiasis (OC) and ocular prognosis with echinocandin therapy for...
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Risk factors and outcomes associated with persistent vancomycin resistant Enterococcal Bacteremia
BackgroundPrior studies have identified that vancomycin resistant enterococcus (VRE) bacteremia that persists for four days or more is an independent...
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A Sco** Review of the Changing Epidemiology and Risk Factors of Endogenous Candida Ocular Infections
Purpose of ReviewThere is controversy surrounding the true incidence of ocular infection in patients with candidemia and the best approach to...
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Candidemia in patients with cardiovascular implantable electronic devices
PurposeCurrent guidelines recommend complete extraction of cardiovascular implantable electronic devices (CIEDs) in the case of persistent or...
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Pharmacological options for Candida albicans Endocarditis at the roadblock with irrecoverable prosthetics and drug interactions: a case report and review of literature
BackgroundCandidemia is the fourth most common nosocomial bloodstream infection. Endocarditis from candidemia is a rare but possibly fatal...
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Candida auris Blood stream infection- a descriptive study from Qatar
BackgroundCandida auris is an emerging yeast pathogen that can cause invasive infections, particularly candidemia, in healthcare settings. Candida...
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Epidemiology, clinical characteristics, and outcome of candidemia in critically ill patients in Germany: a single-center retrospective 10-year analysis
BackgroundDespite advances in the management of bloodstream infections (BSI) caused by Candida spp., the mortality still remains high in critically...
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Candida albicans and Antifungal Peptides
Candida albicans , a ubiquitous opportunistic fungal pathogen, plays a pivotal role in human health and disease. As a commensal organism, it normally...
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Persistent candidemia in very low birth weight neonates: risk factors and clinical significance
BackgroundThe prevalence and risk factors for persistent candidemia among very low birth weight infants are poorly understood. This study aimed to...
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Chronic disseminated candidiasis in a patient with acute leukemia - an illustrative case and brief review for clinicians
Chronic disseminated candidiasis (CDC) is a severe but rarely seen fungal infection presenting in patients with hematologic malignancies after a...
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The Impact of Corticosteroids on the Outcome of Fungal Disease: a Systematic Review and Meta-analysis
Purpose of ReviewCorticosteroids have a complex relationship with fungal disease — risk for many, benefit for others. This systematic review aims to...
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Emerging echinocandin-resistant Candida albicans and glabrata in Switzerland
Echinocandins represent the first-line therapy of candidemia. Echinocandin resistance among Candida spp. is mainly due to acquired FKS mutations. In...
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The Lifesaving Impact of Transcatheter Interventions in the Early Post-Fontan Palliation Period
Despite advancements in postoperative outcomes after Fontan surgery, there remains a risk of suboptimal outcomes and significant morbidity in the...
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Changes in the epidemiology of invasive fungal disease in a Pediatric Hematology and Oncology Unit: the relevance of breakthrough infections
BackgroundInvasive fungal disease (IFD) is a significant cause of morbimortality in children under chemotherapy or hematopoietic stem cell transplant...
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Case report: Candida krusei spondylitis in an immunocompromised patient
BackgroundInvasive infections with Candida krusei are uncommon and rarely complicated by spondylitis. Previous described cases were solely treated...
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Coinfection of fungi with SARS-CoV-2 is a detrimental health risk for COVID-19 patients
BackgroundNotable fungal coinfections with SARS-CoV-2 in COVID-19 patients have been reported worldwide in an alarming way. Mucor spp. and Rhizopus ...
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Empirical Therapy for Invasive Candidiasis in Critically Ill Patients
Purpose of ReviewIn this narrative review, we discuss recent literature regarding early antifungal therapy in critically ill patients, focusing in...