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The regulation of hypoxia-related lncRNAs in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is still a public health disease with its high prevalence and morbidity. Short of early diagnosis biomarkers and...
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Prognostic analysis of hepatocellular carcinoma based on cuproptosis -associated lncRNAs
ObjectivesCuproptosis represents an innovative type of cell death, distinct from apoptosis, driven by copper dependency, yet the involvement of...
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Modulating the Expression of Exercise-induced lncRNAs: Implications for Cardiovascular Disease Progression
Recent research shows exercise is good for heart health, emphasizing the importance of physical activity. Sedentary behavior increases the risk of...
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A novel prognostic model of breast cancer based on cuproptosis-related lncRNAs
ObjectiveBreast cancer (BC) is a deadly form of malignancy responsible for the death of a large number of women every year. Cuproptosis is a newly...
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Identification and bioinformatics analysis of lncRNAs in serum of patients with ankylosing spondylitis
ObjectivesThe aim of this study was to explore the long non-coding RNA (lncRNA) expression profiles in serum of patients with ankylosing spondylitis...
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Identification of functional lncRNAs in atrial fibrillation based on RNA sequencing
BackgroundAtrial fibrillation (AF) is one of the most common arrhythmia contributing to serious conditions such as stroke and heart failure. Recent...
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Comprehensive analysis of serum exosome-derived lncRNAs and mRNAs from patients with rheumatoid arthritis
BackgroundSerum exosomes play important roles in intercellular communication and are promising biomarkers of several autoimmune diseases. However,...
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Mutual interaction of lncRNAs and epigenetics: focusing on cancer
Long noncoding RNAs are characterized as noncoding transcripts longer than 200 nucleotides in response to a variety of functions within the cells....
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Genome-wide investigation of lncRNAs revealed their tight association with gastric cancer
BackgroundGastric cancer (GC) is a significant health issue globally, ranking as the fifth most common cancer with over 10,000 new cases reported...
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Decoding the regulatory landscape of lncRNAs as potential diagnostic and prognostic biomarkers for gastric and colorectal cancers
Colorectal cancer (CRC) and gastric cancer (GC) are major contributors to cancer-related mortality worldwide. Despite advancements in understanding...
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The multifaceted perspectives on the regulation of lncRNAs in hepatocellular carcinoma ferroptosis: from bench-to-bedside
Despite being characterized by high malignancy, high morbidity, and low survival rates, the underlying mechanism of hepatocellular carcinoma (HCC)...
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A nomogram based on 4-lncRNAs signature for improving prognostic prediction of hepatocellular carcinoma
PurposeLong noncoding RNAs (lncRNAs) with abnormal expression are frequently seen in hepatocellular cancer patients (HCC). Previous studies have...
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DNA methylation-related lncRNAs predict prognosis and immunotherapy response in gastric cancer
BackgroundLncRNAs and DNA methylation are both key regulators of tumorigenesis and immune regulation. However, the interaction between lncRNA and DNA...
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Selection of M7G-related lncRNAs in kidney renal clear cell carcinoma and their putative diagnostic and prognostic role
BackgroundKidney renal clear cell carcinoma (KIRC) is a common malignant tumor of the urinary system. This study aims to develop new biomarkers for...
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A combination of cuproptosis and lncRNAs predicts the prognosis and tumor immune microenvironment in cervical cancer
BackgroundCuproptosis induces proteotoxic stress and eventually leads to cell death. However, the relationship between cuproptosis and lncRNAs in...
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Immune-related LncRNAs scores predicts chemotherapeutic responses and prognosis in cervical cancer patients
BackgroundLong non-coding RNAs (LncRNAs) regulating the immune microenvironment of cancer is a hot spot. But little is known about the influence of...
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The role of LncRNAs and CircRNAs in osteoporosis: a focus on osteogenesis and osteoclastogenesis signaling pathways
BackgroundOsteoporosis is a crucial health concern interconnected with physical disabilities as well as financial burdens. It arises from an...
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Unveiling the functional paradigm of exosome-derived long non-coding RNAs (lncRNAs) in cancer: based on a narrative review and systematic review
Background and purposeThe intricate mechanisms underlying intercellular communication within the tumor microenvironment remain largely elusive....
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Construction of lncRNA-m6A gene-mRNA regulatory network to identify m6A-related lncRNAs associated with the progression of lung adenocarcinoma
BackgroundWe evaluated the prognostic value of m6A-related long noncoding RNAs (lncRNAs) in lung adenocarcinoma (LUAD).
MethodsThe expression levels...
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Upregulation of CCNB2 and a novel lncRNAs-related risk model predict prognosis in clear cell renal cell carcinoma
BackgroundClear cell renal cell carcinoma (ccRCC) is the main type of renal cell carcinoma. Cyclin B2 (CCNB2) is a subtype of B-type cyclin that is...
