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Spinal dementia: Don’t miss it, it’s treatable
Background & purposeAround 5% of dementia patients have a treatable cause. To estimate the prevalence of two rare diseases, in which the treatable...
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Intraoperative MRI without an intraoperative MRI suite: a workflow for glial tumor surgery
BackgroundIntraoperative MRI (iMRI) has emerged as a useful tool in glioma surgery to safely improve the extent of resection. However, iMRI requires...
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A cross-sectional survey assessing clinicians’ perspectives towards redesigning the surveillance model for head and neck cancer: can we do better?
BackgroundService delivery of post-treatment surveillance in head and neck cancer (HNC) varies across institutions in Australia. To better understand...
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Immune responses to oligomeric α-synuclein in Parkinson’s disease peripheral blood mononuclear cells
Parkinson’s disease displays clinical heterogeneity, presenting with motor and non-motor symptoms. Heterogeneous phenotypes, named brain-first and...
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Neurological and Psychiatric Clinical Manifestations of Sjögren Syndrome
Purpose of ReviewSjögren Syndrome is a systemic autoimmune disorder that presents mainly with sicca symptoms, but frequently affects other body...
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Pediatric shunt failure in a resource limited Lower-Middle Income Country (LMIC) institution in La Paz, Bolivia
BackgroundShunt failure is an undesirable but common occurrence following neurosurgical shunting for pediatric hydrocephalus. Little is known about...
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Risk factors of prognosis for spontaneous cerebellar hemorrhage: a systematic review and meta-analysis
BackgroundThe most deadly type of spontaneous intracerebral hemorrhage is spontaneous cerebellar hemorrhage (SCH). The purpose of this meta-analysis...
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Validity and accuracy of automatic cobb angle measurement on 3D spinal ultrasonographs for children with adolescent idiopathic scoliosis: SOSORT 2024 award winner
PurposeUltrasonography for scoliosis is a novel imaging method that does not expose children with adolescent idiopathic scoliosis (AIS) to radiation....
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Effectiveness of personalized rehabilitation in adults suffering from persistent concussion symptoms as compared to usual care: a randomized control trial protocol
BackgroundSymptoms reported by patients who sustain a concussion are non-specific. As such, clinicians are better able to manage patients when a...
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Association of hemoglobin drift and outcomes in patients with aneurysmal subarachnoid hemorrhage
The relationship between in-hospital hemoglobin (Hb) drift and outcomes in patients undergoing surgical clip** for aneurysmal subarachnoid...
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Elevated serum kynurenic acid in individuals with first-episode psychosis and insufficient response to antipsychotics
The tryptophan-metabolizing kynurenine pathway (KP) can be activated by enhanced inflammatory responses and has been implicated in the...
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The Therapeutic Effect of Bleomycin Sclerotherapy in Vascular Malformations
Sclerotherapy is a frequently employed technique for treating vascular malformations. Bleomycin is a sclerosant that has demonstrated efficacy and...
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Decreased DTI-ALPS index in delirium: a preliminary MRI study
PurposeDelirium is linked to brain abnormalities, yet the role of the glymphatic system is not well understood. This study aims to examine...
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To scan or not to scan? A retrospective cohort study analysing the efficacy of routine post-operative CT after brain biopsy
PurposePostoperative management following elective cranial surgery, particularly after biopsy procedures, varies significantly across neurosurgical...
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Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases
Proteolytic cell surface release (‘shedding’) of the prion protein (PrP), a broadly expressed GPI-anchored glycoprotein, by the metalloprotease...
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Evaluating the Impact of Point-of-Care Electroencephalography on Length of Stay in the Intensive Care Unit: Subanalysis of the SAFER-EEG Trial
BackgroundElectroencephalography (EEG) is needed to diagnose nonconvulsive seizures. Prolonged nonconvulsive seizures are associated with neuronal...
