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Does bilateral Wilms’ tumor involving the collecting system in children have a worse prognosis?
BackgroundThe literature on nephron-sparing surgery (NSS) in children with bilateral Wilms’ tumors (BWT) involving the collection system is mostly...
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Responding to the workforce crisis: consensus recommendations from the Second Workforce Summit of the American Society of Pediatric Nephrology
ImportancePediatric patients with complex medical problems benefit from pediatric sub-specialty care; however, a significant proportion of children...
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Biological determinants of PSMA expression, regulation and heterogeneity in prostate cancer
Prostate-specific membrane antigen (PSMA) is an important cell-surface imaging biomarker and therapeutic target in prostate cancer. The PSMA-targeted...
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Machine learning models to predict systemic inflammatory response syndrome after percutaneous nephrolithotomy
ObjectiveThe objective of this study was to develop and evaluate the performance of machine learning models for predicting the possibility of...
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Kardiale Kanalopathien im Kontext hereditärer Arrhythmiesyndrome
Genetic arrhythmia disorders are rare diseases; however, they are a common cause of sudden cardiac death in children, adolescents, and young adults....
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Association of Urinary Incontinence with Sensory-Motor Performance in Women with Multiple Sclerosis
Introduction and HypothesisThe relationship between somatosensory and motor components of urinary incontinence in individuals with MS has not been...
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The contribution of E3D imaging integrated with robotic navigation: analysis of the first 80 consecutive posterior spinal fusion cases
Eighty consecutive complex spinal robotic cases utilizing intraoperative 3D CT imaging (E3D, Group 2) were compared to 80 age-matched controls using...
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Treatment of chronic kidney disease in older populations
As the world population ages, an expected increase in the prevalence of chronic kidney disease (CKD) among older individuals will pose a considerable...
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Case presentation: a severe case of cobalamin c deficiency presenting with nephrotic syndrome, malignant hypertension and hemolytic anemia
BackgroundThe etiology of nephrotic syndrome can vary, with underlying metabolic diseases being a potential factor. Cobalamin C (cblC) defect is an...
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Osimertinib in a patient with end-stage kidney disease not on hemodialysis
Osimertinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) effective in non- small cell lung cancer (NSCLC) with EGFR...
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Genetic biomarkers of cognitive impairment and dementia of potential interest in CKD patients
This review discusses genetic variants associated with cognitive dysfunction in chronic kidney disease (CKD) patients, emphasising the limited...
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Favorable changes in the eGFR slope after dapagliflozin treatment and its association with the initial dip
BackgroundRenoprotective effects of sodium glucose transporter 2 (SGLT2) inhibitors, including dapagliflozin, were observed in randomized controlled...
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Mind the gap in kidney care: translating what we know into what we do
Historically, it takes an average of 17 years to move new treatments from clinical evidence to daily practice. Given the highly effective treatments...
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Guidelines for clinical evaluation of chronic kidney disease in early stages
BackgroundFor the development of pharmaceutical products in kidney field, appropriate surrogate endpoints which can predict long-term prognosis are...
