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Diacerein mitigates endocrine and cardio-metabolic disruptions in experimental PCOS mice model by modulating AdipoR1/ PON 1
BackgroundThis study aimed to explore the impact of Diacerein (DIC) on endocrine and cardio-metabolic changes in polycystic ovarian syndrome (PCOS)...
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Assessment of the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS™) with modification of the management recommendations for pediatric thyroid nodules
BackgroundThyroid nodules are unusual in children, but when present, they carry a higher risk for malignancy, as compared to adults. Several...
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Refractory type 1 plastic bronchitis in a child; case report
BackgroundPlastic bronchitis (PB) is a rare pediatric pulmonary condition characterized by the production of branching bronchial casts that cause...
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Transient secondary pseudo-hypoaldosteronism in infants with urinary tract infections: systematic literature review
Infants with a congenital anomaly of the kidney and urinary tract sometimes present with hyponatremia, hyperkalemia, and metabolic acidosis due to...
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Trichohepatoenteric syndrome type 1: expanding the clinical spectrum of THES type 1 due to a homozygous variant in the SKIC3 gene
Trichohepatoenteric syndrome (THES), also known as phenotypic diarrhea or syndromic diarrhea, is a rare autosomal recessive genetic disorder caused...
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PICC tip dislodgement causing massive pleural effusion and atelectasis with acute respiratory failure: a case report
Peripheral intravenous central catheter (PICC) is a common tool for intravenous infusion for children who need central venous access. Although it is...
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Dried fruit intake and lower risk of type 2 diabetes: a two-sample mendelian randomization study
BackgroundPrevious studies have shown controversy about whether dried fruit intake is associated with type 2 diabetes. This study aimed to examine...
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Hospitalization- and death-related financial and employment effects in parents of children with life-limiting conditions: a fixed-effects analysis
The purpose of this study is to investigate out-of-pocket non-medical expenses and employment-related outcomes in families of children with...
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Magnetic Seizure Therapy in Management of Depression: A Narrative Review
Purpose of ReviewThis review aims to discuss historical aspects, mechanism of action, safety and efficacy, response predictors, and Magnetic Seizure...
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Efficacy and safety of oral semaglutide monotherapy vs placebo in a predominantly Chinese population with type 2 diabetes (PIONEER 11): a double-blind, Phase IIIa, randomised trial
Aims/hypothesisThe aim of this study was to evaluate the efficacy and safety of oral semaglutide monotherapy vs placebo in a predominantly Chinese...
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A mixed meal tolerance test predicts onset of type 2 diabetes in Southwestern Indigenous adults
Background/ObjectiveTo identify predictors of incident type 2 diabetes using a mixed meal tolerance test (MMTT).
MethodsAdult Indigenous Americans...
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Molecular circadian clock disruption in the leukocytes of individuals with type 2 diabetes and overweight, and its relationship with leukocyte–endothelial interactions
Aims/hypothesisAlterations in circadian rhythms increase the likelihood of develo** type 2 diabetes and CVD. Circadian rhythms are controlled by...
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Caregiver-reported emotional-behavioral symptoms in Spanish youth during the COVID-19 pandemic: a longitudinal study
BackgroundCOVID-19 pandemic stressors affected youth’s mental health. This longitudinal study aims to explore these effects while considering...
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Longitudinal program evaluation of an inter-institutional mentorship network for pediatric rheumatology using a quality improvement framework
BackgroundThe American College of Rheumatology (ACR)/Childhood Arthritis and Rheumatology Research Alliance (CARRA) Mentoring Interest Group (AMIGO)...
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Implementation of remote general movement assessment using the in-motion instructions in a high-risk norwegian cohort
BackgroundGeneral Movement Assessment (GMA) is recommended for early detection of risk for cerebral palsy but requires trained clinical experts. We...
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Relationship between non-alcoholic fatty liver and progressive fibrosis and serum 25-hydroxy vitamin D in patients with type 2 diabetes mellitus
ObjectiveWe aimed to analyze the relationship between non-alcoholic fatty liver and progressive fibrosis and serum 25-hydroxy vitamin D (25(OH)D) in...
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Review on the role of hypothalamic astrocytes in the neuroendocrine control of metabolism
Astrocytes are the most numerous type of glial cells found in the nervous system. They regulate energy homeostasis in collaboration with the neuronal...
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The longitudinal growth trajectory of children with congenital hypothyroidism during the first 3 years of life
Congenital hypothyroidism (CH) is detected through a newborn screening program in Iran, enabling early detection and prompt treatment. This study...