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Prolonged water-only fasting in the management of low-grade follicular lymphoma: a case series
BackgroundFollicular lymphoma typically follows an indolent and relapsing course often requiring several treatment cycles to achieve remission. Some...
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Semaphorin 3C (Sema3C) reshapes stromal microenvironment to promote hepatocellular carcinoma progression
More than 90% of hepatocellular carcinoma (HCC) cases develop in the presence of fibrosis or cirrhosis, making the tumor microenvironment (TME) of...
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In silico exploration of anti-prostate cancer compounds from differential expressed genes
Prostate cancer (PCa) is a complex and biologically diverse disease with no curative treatment options at present. This study aims to utilize...
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Vertebral bone quality score was associated with paraspinal muscles fat infiltration, but not modic classification in patients with chronic low back pain: a prospective cross-sectional study
BackgroundThe lumbar vertebra and paraspinal muscles play an important role in maintaining the stability of the lumbar spine. Therefore, the aim of...
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Immune checkpoint inhibitors-induced diabetes mellitus (review)
Immune checkpoint inhibitors (ICIs) have become extensively utilized in the early-stage treatment of various cancers, offering additional therapeutic...
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Detectability of intracranial vessel wall atherosclerosis using black-blood spectral CT: a phantom and clinical study
BackgroundComputed tomography (CT) is the usual modality for diagnosing stroke, but conventional CT angiography reconstructions have limitations.
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Neuropsychological complications of hypoprolactinemia
Prolactin (PRL) is primarily produced by the pituitary lactotrophic cells and while initially named for its role in lactation, PRL has several other...
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Forecasting and map** dengue fever epidemics in China: a spatiotemporal analysis
BackgroundDengue fever (DF) has emerged as a significant public health concern in China. The spatiotemporal patterns and underlying influencing its...
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Reduction in ACE2 expression in peripheral blood mononuclear cells during COVID-19 – implications for post COVID-19 conditions
BackgroundSevere COVID-19 is uncommon, restricted to 19% of the total population. In response to the first virus wave (alpha variant of SARS-CoV-2),...
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Skin graft surgery and its impact on platelet counts in Iranian burn patients: a non-randomized clinical trial
BackgroundPlatelets are critical in maintaining homeostasis and immune response in burn patients. The concentration of platelets decreases in burn...
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Inappropriate treatment of pulmonary aspergillosis caused by Aspergillus flavus in susceptible pediatric patients: a case series
BackgroundPulmonary aspergillosis is a prevalent opportunistic fungal infection that can lead to mortality in pediatric patients with underlying...
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Neuroimmune crosstalk
Cardiovascular diseases are the leading cause of death worldwide. Pathophysiologically, metabolic and inflammatory processes contribute substantially...
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SARS-CoV-2 in Mozambican primary school-aged children at Maputo City and Province: a cross-sectional study from a low-income country
BackgroundSeroprevalence studies provide information on the true extent of infection and capture demographic and geographic differences, indicating...
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Identification of seniors at risk (ISAR) score and potentially inappropriate prescribing: a retrospective cohort study
BackgroundPotentially inappropriate prescribing (PIP) is usually associated with a higher risk of adverse health outcomes. It is therefore important...
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Pancreatic cancer cell- and cancer-associated fibroblast-derived exosomes in disease progression, metastasis, and therapy
Exosomes play a crucial role in the progression and spread of pancreatic cancer, serving not only as promoters of tumor growth and organ-specific...
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Comparison of microscopic and xpert MTB diagnoses of presumptive mycobacteria tuberculosis infection: retrospective analysis of routine diagnosis at Cape Coast Teaching Hospital
IntroductionTuberculosis is a global health problem that causes 1. 4 million deaths every year. It has been estimated that sputum smear-negative...
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Assessment of the Efficacy and Durability of IncobotulinumtoxinA in the Treatment of the Upper Face in Adult Women
IntroductionIncobotulinumtoxinA (Xeomin®) is used in the treatment of dynamic wrinkles and the aesthetic repositioning of facial structures. The...
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Single-Center Randomized Trial Comparing Feeding Jejunostomy with Nasojejunal Tube Placement in Patients Undergoing Transhiatal Esophagectomy Post-Neoadjuvant Therapy for Esophageal Cancer
BackgroundEnteral nutrition is the preferred mode of nutrition following esophagectomy. However, the preferred mode of enteral nutrition (feeding...
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Paracetamol overdose causing acute kidney injury without hepatotoxicity: a case report
BackgroundParacetamol is a widely used analgesic and antipyretic. Paracetamol-induced hepatotoxicity is well known, but nephrotoxicity without...
