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Psychosocial and biological pathways to aging
While the biological hallmarks of aging are widely recognized as fundamental mechanisms of biological aging, more recently, there have been calls...
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Patients with High Baseline Neutrophil-to-Lymphocyte Ratio Exhibit Better Response to Filgotinib as Treatment for Rheumatoid Arthritis
IntroductionHigh baseline neutrophil-to-lymphocyte ratio (NLR) in rheumatoid arthritis (RA) has been associated with positive responses to biologic...
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Butyrate and tributyrin reduce LPS-induced inflammatory cytokine production from human visceral fat
IntroductionThe current obesity crisis has resulted in many people with excess adipose tissue suffering from chronic inflammation. This inflammation...
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A retrospective analysis of treatment patterns, overall survival, and real-world disease-free survival in early-stage non-small cell lung cancer following complete resection
BackgroundReal-world data regarding patient characteristics, adjuvant treatment patterns, and long-term survival outcomes are needed to better...
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Normalized lactate load as an independent prognostic indicator in patients with cardiogenic shock
BackgroundEarly prognosis evaluation is crucial for decision-making in cardiogenic shock (CS) patients. Dynamic lactate assessment, for example,...
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An unenhanced 3D-FLAIR sequence using long repetition time and constant flip angle to image endolymphatic hydrops
ObjectivesTo evaluate a three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) sequence using a long repetition time (TR) and constant flip...
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Depressive symptoms as risk factors for the onset of home hypertension: a prospective cohort study
Depression is comorbid with somatic diseases; however, the relationship between depressive symptoms and hypertension (HT), a risk factor for...
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Effects of polygenic risk score and sodium and potassium intake on hypertension in Asians: A nationwide prospective cohort study
Genetic factors, lifestyle, and diet have been shown to play important roles in the development of hypertension. Increased salt intake is an...
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Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and disease
Wnts are secreted, lipid-modified proteins that bind to different receptors on the cell surface to activate canonical or non-canonical Wnt signaling...
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Differentiating between benign and malignant breast lesions using dual-energy CT-based model: development and validation
ObjectivesTo develop and validate a dual-energy CT (DECT)-based model for noninvasively differentiating between benign and malignant breast lesions...
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“Textbook outcome(s)” in colorectal surgery: a systematic review and meta-analysis
BackgroundTextbook outcome (TO) is a composite measure used in surgery to evaluate post operative outcomes. No review has synthesised the evidence in...
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Community-based exercises improve health status in pre-frail older adults: A systematic review with meta-analysis
BackgroundPre-frailty is associated with increased healthcare utilization. Over the past decade, public health interventions such as community-based...
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Deep learning in pulmonary nodule detection and segmentation: a systematic review
ObjectivesThe accurate detection and precise segmentation of lung nodules on computed tomography are key prerequisites for early diagnosis and...
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Welches Potential hat ChatGPT 3.5 für eine qualifizierte Patienteninformation?
IntroductionThe chatbot ChatGPT represents a milestone in the interaction between humans and large databases that are accessible via the internet. It...
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Bioactivity and antibacterial effect of star anise biosynthesized silver nanoparticles against Streptococcus mutans: an in vitro study
BackgroundSilver nanoparticles (AgNPs) are receiving a lot of attention as a prospective antibacterial agent for use in caries prevention. The...
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Seagrass as a potential nutraceutical to decrease pro-inflammatory markers
BackgroundThe Pro-inflammatory mediators such as prostaglandin E2, nitric oxide and TNF-α are the key players in the stimulation of the inflammatory...
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Analysis of the impact of a university distance learning course on digitalization in medicine on students and healthcare professionals
PurposeThe public medical universities in Austria (educating 11,000 students) developed a joint public distance learning series in which clinicians...