Search
Search Results
-
Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h
Aims/hypothesisDisruption of pancreatic islet function and glucose homeostasis can lead to the development of sustained hyperglycaemia, beta cell...
-
Trajectories of BMI before and after diagnosis of type 2 diabetes in a real-world population
Aims/hypothesisFew studies have examined the clinical characteristics associated with changes in weight before and after diagnosis of type 2...
-
Causal relationship between bone mineral density and intervertebral disc degeneration: a univariate and multivariable mendelian randomization study
BackgroundAlthough previous studies have suggested a possible association between bone mineral density (BMD) and intervertebral disc degeneration...
-
Higher fibre and lower carbohydrate intake are associated with favourable CGM metrics in a cross-sectional cohort of 470 individuals with type 1 diabetes
Aims/hypothesisThe aim of this work was to investigate the association between macronutrient intakes and continuous glucose monitoring (CGM) metrics...
-
Exploring the shift in newborn care practices among mothers and grandmothers in rural Odisha, India — a qualitative study
BackgroundThis study delves into newborn care and infant-feeding practices in rural Odisha, specifically focusing on the rural KBK + region of Odisha...
-
Cost avoidance of pharmacist-led deprescribing using STOPPFrail for older adults in nursing homes
BackgroundThe Screening Tool of Older Persons Prescriptions in Frail adults with limited life expectancy (STOPPFrail) criteria aim to reduce...
-
Establishment of an ovarian cancer exhausted CD8+T cells-related genes model by integrated analysis of scRNA-seq and bulk RNA-seq
Ovarian cancer (OC) was the fifth leading cause of cancer death and the deadliest gynecological cancer in women. This was largely attributed to its...
-
-
Predictors of daytime blood pressure, nighttime blood pressure, and nocturnal dip** in patients with chronic kidney disease
Increasing attention has recently been paid to discrepancies between office and ambulatory blood pressure (BP) control in patients with chronic...
-
The effect of transcranial alternating current stimulation on cognitive flexibility and attention of children with intellectual disability: a case report
BackgroundIntellectual disability is a neurodevelopmental disorder characterized by significant impairments in intellectual functioning and adaptive...
-
Sample size calculation for data reliability and diagnostic performance: a go-to review
Sample size, namely the number of subjects that should be included in a study to reach the desired endpoint and statistical power, is a fundamental...
-
Comparison of the clinical efficacy and prognosis of the two techniques for treating partial articular-sided supraspinatus tendon tears under arthroscopy
BackgroundAt present, shoulder arthroscopy is usually used for treatment of rotator cuff injuries. There is still debate over the precise technique...
-
-
Effect of body mass index on 30-day complication rate and implant survival rate after simultaneous bilateral unicompartmental knee arthroplasty: a multicentre retrospective study
ObjectiveThe practice of simultaneous bilateral unicompartmental knee arthroplasty (SBUKA) remains a topic of debate, particularly in patients with...
-
Highly extensile approach for comminuted ulna coronoid process fractures with mini-plate fixation: a case series of 31 patients
BackgroundFor the treatment of coronoid process fractures, medial, lateral, anterior, anteromedial, and posterior approaches have been increasingly...
-
Nogapendekin alfa Inbakicept: First Approval
Nogapendekin alfa inbakicept (ANKTIVA ® ; nogapendekin alfa inbakicept-pmln) is a recombinant interleukin-15 (IL-15) superagonist protein complex being...
-
Evolving Concepts of Pain Management in Elderly Patients
Purpose of ReviewThe elderly population typically suffer from a variety of diseases that mostly reflect the degenerative changes linked with the...
-
Givinostat: First Approval
Givinostat (DUVYZAT™), an orally available histone deacetylase inhibitor, is being developed by Italfarmaco for the treatment of muscular dystrophy...
-
Oncogenic dependency on SWI/SNF chromatin remodeling factors in T-cell acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is a hematological malignancy arising from immature thymocytes. Unlike well-known oncogenic transcription...
