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Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...
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Prediction of microvascular invasion in hepatocellular carcinoma patients with MRI radiomics based on susceptibility weighted imaging and T2-weighted imaging
BackgroundThe accurate identification of microvascular invasion (MVI) in patients with hepatocellular carcinoma (HCC) is of great clinical importance.
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Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey
PurposeThis study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...
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A scarce combination of arterial variants: an occipital artery originating from the internal carotid artery associated with a linguofacial trunk
The occipital artery (OA) typically originates from the external carotid artery (ECA). Variations of the ECA has been well described in the current...
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Safety and Efficacy of Covered Self-Expandable Metallic Stent for Choledochojejunal Anastomotic Stricture: A Multi-Center Retrospective Cohort Study
BackgroundBenign choledochojejunal anastomotic stricture (CJS) is a complication of pancreaticoduodenectomy and choledochojejunostomy. Typically...
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Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study
PurposeNeoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response...
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Hyponatremia Is Associated with Mortality in Acute Pancreatitis Patients
BackgroundDisorders of serum sodium are common among general patients and are associated with poor outcomes. The prognostic value of serum sodium...
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An evaluation of morphometry and dehiscence of facial canal: a systematic review and meta-analysis of observational studies
IntroductionThe facial canal (FC) is an extensive bony canal that houses the facial nerve and occupies a central position in the petrous part of...
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Statins for the Primary Prevention of Anthracycline Cardiotoxicity: A Comprehensive Review
Purpose of ReviewThe aim of this review is two-fold: (1) To examine the mechanisms by which statins may protect from anthracycline-induced...
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Reducing racial and ethnic disparities in cardiovascular outcomes among cancer survivors
Purpose of reviewAnalyze current evidence on racial/ethnic disparities in cardiovascular outcomes among cancer survivors, identifying factors and...
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Rare tumours of the pancreas: monocentric study
PurposeThe biology of rare pancreatic tumours, which differs from that of ductal pancreatic cancer, requires increased attention. Although the...
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3D mobile regression vision transformer for collateral imaging in acute ischemic stroke
PurposeThe accurate and timely assessment of the collateral perfusion status is crucial in the diagnosis and treatment of patients with acute...
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Differences in severity of chemotherapy-induced nausea and vomiting between neoadjuvant and adjuvant chemotherapy in patients with breast cancer: analysis of data from two prospective observational studies
PurposeWe assessed the differences in chemotherapy-induced nausea and vomiting (CINV) severity in patients with breast cancer, receiving neoadjuvant...
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Regional Heterogeneity in Intestinal Epithelial Barrier Permeability and Mesenteric Perfusion After Thoracic Spinal Cord Injury
BackgroundSpinal cord injury (SCI) disrupts intestinal barrier function, thereby increasing antigen permeation and leading to poor outcomes. Despite...
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Systematic review: genetic polymorphisms in the pharmacokinetics of high-dose methotrexate in pediatric acute lymphoblastic leukemia patients
Variations in pharmacokinetic responses to high-dose methotrexate are essential for the prognosis and management of toxicity in the treatment of...
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Targeting the pancreatic tumor microenvironment by plant-derived products and their nanoformulations
Pancreatic cancer remains a significant health issue with limited treatment options. The tumor stroma, a complex environment made up of different...
