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A phase 3, randomized, double-blind, multicenter, placebo-controlled study of S-588410, a five-peptide cancer vaccine as an adjuvant therapy after curative resection in patients with esophageal squamous cell carcinoma
BackgroundS-588410, a cancer peptide vaccine (CPV), comprises five HLA-A*24:02-restricted peptides from five cancer-testis antigens. In a phase 2...
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Combining multimodal diffusion-weighted imaging and morphological parameters for detecting lymph node metastasis in cervical cancer
BackgroundAccurate detection of lymph node metastasis (LNM) is crucial for determining the tumor stage, selecting optimal treatment, and estimating...
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Targeted redox-responsive peptide for arterial chemoembolization therapy of orthotropic hepatocellular carcinoma
ObjectiveTranscatheter Arterial Chemoembolization (TACE) is the first choice for the treatment of advanced-stage hepatocellular carcinoma (HCC)....
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Predictive risk factors for resection surface-related complications after laparoscopic simultaneous resection of primary colorectal tumor and synchronous liver metastases: a single-center retrospective study
BackgroundLaparoscopic simultaneous resection (LSR) of primary colorectal tumors and synchronous colorectal liver metastases (sCRLM) has been...
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From FUSE to a hands-on electrosurgery course using a cadaveric model
IntroductionSurgical procedures in contemporary practice frequently employ energy-based devices, yet comprehensive education surrounding their safety...
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Weight loss after Roux-en-Y gastric bypass and single anastomosis duodenoileostomy following failed sleeve gastrectomy
ObjectiveWhile sleeve gastrectomy (SG) results in sustained weight loss for the majority of patients, some will experience inadequate weight loss or...
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Cascade (cup and spill) stomach
Graphical abstract
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Efficacy and outcomes of per oral plication of the (neo)esophagus (POPE) for impaired emptying in achalasia and post-esophagectomy patients
BackgroundPer-oral plication of the (neo)esophagus (POPE) is an endoscopic procedure used to improve emptying of the defunctionalized esophagus or...
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Letter to the Editor on “Radiologic serosal invasion sign as a new criterion of T4a gastric cancer on computed tomography: diagnostic performance and prognostic significance in patients with advanced gastric cancer”
We provide commentary on the paper by You et al., which proposed the ‘serosal invasion sign’ as a new criterion for T4a gastric cancer on CT. We...
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Self-assembled nanoparticles of costunolide and glycyrrhizic acid for enhanced ulcerative colitis treatment
Ulcerative colitis (UC) is a persistent inflammatory condition that specifically targets the colon and rectum. Existing therapies fail to adequately...
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Successful intrahepatic cholangiocarcinoma conversion surgery after administration of fibroblast growth factor receptor inhibitor
We describe a case of a 47-year-old male patient with initially unresectable intrahepatic cholangiocarcinoma of the right liver lobe with tumor...
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Conditional survival and the prognostic value of serum carcinoembryonic antigen level in oldest old with colorectal cancer
BackgroundTo evaluate the clinical value of serum CEA levels and their implications on the diagnostic value of the conventional TNM staging system in...
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Urologic prosthetics: an imaging review of short- and long-term complications
PurposeUrologic prosthetics offer significant quality of life enhancements for patients with stress urinary incontinence and erectile dysfunction....
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Comparison of low versus high (standard) intraabdominal pressure during laparoscopic colorectal surgery: systematic review and meta-analysis
BackgroundTo evaluate outcomes of low with high intraabdominal pressure during laparoscopic colorectal resection surgery.
MethodsA systematic search...
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Radiologic evaluation of the kidney transplant donor and recipient
The kidney is the most common solid organ transplant globally and rates continue to climb, driven by the increasing prevalence of end stage renal...
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Network analysis of gut microbial communities reveal key genera for a multiple sclerosis cohort with Mycobacterium avium subspecies paratuberculosis infection
BackgroundIn gut ecosystems, there is a complex interplay of biotic and abiotic interactions that decide the overall fitness of an individual....
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Features associated with clinically actionable hyperechoic hepatic lesions to determine the need for follow-up
PurposeTo evaluate the rate of hyperechoic liver lesions that are clinically actionable and evaluate imaging and clinical factors associated with...
