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The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice
BackgroundThis study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk...
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Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases
Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells. Whether...
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Real world treatment outcomes in polypoidal choroidal vasculopathy in a Caucasian population of British ethnicity
PurposeTo assess treatment response of Polypoidal choroidal vasculopathy (PCV) in a Caucasian population of British ethnicity with intravitreal...
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Sodium tanshinone IIA sulfonate protects vascular relaxation in ApoE-knockout mice by inhibiting the SYK-NLRP3 inflammasome-MMP2/9 pathway
BackgroundHyperlipidemia damages vascular wall and serves as a foundation for diseases such as atherosclerosis, hypertension and stiffness. The...
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Hemophagocytic Lymphohistiocytosis for the Inpatient Dermatologist
Hemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening condition characterized by dysregulation of the immune system leading to...
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Exploring paramedics’ lived experiences in confrontation with patients’ death during missions: a phenomenological study
BackgroundEmergency personnel are the first line of emergency response systems to respond to emergencies; in essence, they are usually exposed to a...
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Improving the introduction of telemedicine in pre-hospital emergency medicine: understanding users and how acceptability, usability and effectiveness influence this process
IntroductionIncreasing numbers of ambulance calls, vacant positions and growing workloads in Emergency Medicine (EM) are increasing the pressure to...
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Mucinous tubular and spindle renal cell carcinoma revealed by a trauma of the kidney: a case report
BackgroundMucinous tubular and spindle cell carcinoma is a rare renal tumor. It has been recognized as a distinct entity in the 2004 World Health...
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Enhancing the Utility of the Moral Injury Experience Wheel: Manualized Applications for Diverse Contexts
Moral injury has emerged as an important construct for understanding the distress experienced in the aftermath of a moral violation, initially among...
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Hospital personnel perspectives on factors influencing acute care patient outcomes: a qualitative approach to model refinement
BackgroundHealth systems have long been interested in the best practices for staffing in the acute care setting. Studies on staffing often focus on...
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Bezold’s abscess, an uncommon complication of otitis media and cholesteatoma: a case report
BackgroundMastoiditis frequently occurs in children as they are more susceptible to middle ear infections, but infrequently occurs in adults. A rare...
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Initial surgery for spontaneous intestinal perforation in extremely low birth weight infants is not associated with mortality or in-hospital morbidities
ObjectiveDetermine short-term outcomes following peritoneal drain (PD), laparotomy (LAP) after PD (PD-LAP), and LAP in extremely low birth weight...
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Postoperative EEG abnormalities in relation to neurodevelopmental outcomes after pediatric cardiac surgery
BackgroundWe had reported that postoperative EEG background including sleep-wake cycle (SWC) and discharge (seizures, spikes/sharp waves)...
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Healthy lifestyle index development and its association with type 2 diabetes mellitus status among teachers
BackgroundType 2 diabetes mellitus (T2DM) is a significant health concern and imposes a substantial burden on society. Although leading a healthy...
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Biliary atresia
Biliary atresia (BA) is a progressive inflammatory fibrosclerosing disease of the biliary system and a major cause of neonatal cholestasis. It...
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The spectrum of health conditions in community-based cross-sectional surveys in Southeast Asia 2010-21: a sco** review
BackgroundSoutheast Asia is undergoing an epidemiological transition with non-communicable illnesses becoming increasingly important, yet infectious...
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Unravelling factors influencing demand for modern contraception and evaluating coverage progress since 2015 in Ethiopia, Kenya, and Nigeria: insights from multilevel and geostatistical modelling
IntroductionThe United Nations established the Sustainable Development Goals (SDGs) in 2015 to enhance global development. In this study, we examine...
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Assessing knowledge of hypertension and diabetes mellitus among informal healthcare providers in urban slums in southeastern Nigeria
Informal healthcare providers (IHPs) often serve as the first point of contact for healthcare services for non-communicable diseases in urban slums...
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A two-pronged approach to understanding reciprocity and mental health relationship in develo** countries: evidence from young informal construction workers in Nigeria
BackgroundMental health problems disproportionately affect young people in develo** countries. However, there is limited research on help-seeking...