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Central nervous system involvement in chronic lymphocytic leukemia: a case report and review of literature
BackgroundCentral nervous system involvement in chronic lymphocytic leukemia rarely occurs, and there is no standard therapy for central nervous...
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PICC tip dislodgement causing massive pleural effusion and atelectasis with acute respiratory failure: a case report
Peripheral intravenous central catheter (PICC) is a common tool for intravenous infusion for children who need central venous access. Although it is...
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Conditional survival and the prognostic value of serum carcinoembryonic antigen level in oldest old with colorectal cancer
BackgroundTo evaluate the clinical value of serum CEA levels and their implications on the diagnostic value of the conventional TNM staging system in...
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Zinc finger 259 gene polymorphisms in Egyptian patients with metabolic syndrome and its association with dyslipidemia
BackgroundZinc finger protein 1 (ZPR1), encoded by the ZNF259 gene, plays crucial roles in transcriptional regulation and cell cycle progression....
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Dietary diversity and iron deficiency anemia among a cohort of singleton pregnancies: a cross-sectional study
BackgroundIron deficiency anemia (IDA) is considered one of the most common medical disorders observed during pregnancy. In low- and middle-income...
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Randomized investigation of increased dialyzer membrane hydrophilicity on hemocompatibility and performance
BackgroundHemodialyzers should efficiently eliminate small and middle molecular uremic toxins and possess exceptional hemocompatibility to improve...
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Refractory type 1 plastic bronchitis in a child; case report
BackgroundPlastic bronchitis (PB) is a rare pediatric pulmonary condition characterized by the production of branching bronchial casts that cause...
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Comparison of low versus high (standard) intraabdominal pressure during laparoscopic colorectal surgery: systematic review and meta-analysis
BackgroundTo evaluate outcomes of low with high intraabdominal pressure during laparoscopic colorectal resection surgery.
MethodsA systematic search...
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Molecular circadian clock disruption in the leukocytes of individuals with type 2 diabetes and overweight, and its relationship with leukocyte–endothelial interactions
Aims/hypothesisAlterations in circadian rhythms increase the likelihood of develo** type 2 diabetes and CVD. Circadian rhythms are controlled by...
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Depressive symptoms as risk factors for the onset of home hypertension: a prospective cohort study
Depression is comorbid with somatic diseases; however, the relationship between depressive symptoms and hypertension (HT), a risk factor for...
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Effects of polygenic risk score and sodium and potassium intake on hypertension in Asians: A nationwide prospective cohort study
Genetic factors, lifestyle, and diet have been shown to play important roles in the development of hypertension. Increased salt intake is an...
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Differentiating between benign and malignant breast lesions using dual-energy CT-based model: development and validation
ObjectivesTo develop and validate a dual-energy CT (DECT)-based model for noninvasively differentiating between benign and malignant breast lesions...
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“Textbook outcome(s)” in colorectal surgery: a systematic review and meta-analysis
BackgroundTextbook outcome (TO) is a composite measure used in surgery to evaluate post operative outcomes. No review has synthesised the evidence in...
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Hepatitis B virus in Egypt: the whole story
Hepatitis B virus (HBV) infection is a significant global public health threat with variable geographical distribution. Chronic infection with HBV...
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Normalized lactate load as an independent prognostic indicator in patients with cardiogenic shock
BackgroundEarly prognosis evaluation is crucial for decision-making in cardiogenic shock (CS) patients. Dynamic lactate assessment, for example,...
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Causal inference of the effect of blood proteome on the risk of head and neck cancer: two-sample Mendelian randomization
Early diagnosis of head and neck cancer can improve therapeutic outcomes but remains a challenge. The blood proteome can comprise a key source of...
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Comparison between head rotation and standard techniques for i-gel™ insertion: a randomized controlled trial
BackgroundThis study evaluated the effect of head rotation on the first-attempt success rate of i-gel insertion, aiming to alleviate the effect of...
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Implementation of remote general movement assessment using the in-motion instructions in a high-risk norwegian cohort
BackgroundGeneral Movement Assessment (GMA) is recommended for early detection of risk for cerebral palsy but requires trained clinical experts. We...
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Extrakorporale Erregerelimination mit biomimetischem Adsorber – eine neue Therapiestrategie für die Intensivmedizin
BackgroundIn 2019 the World Health Organization (WHO) listed antimicrobial resistance among the top 10 threats to global health. The Seraph® 100...