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Sleep as a driver of pre- and postnatal brain development
AbstractIn 1966, Howard Roffwarg proposed the ontogenic sleep hypothesis, relating neural plasticity and development to rapid eye movement (REM)...
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Predictive modeling of perioperative patient deterioration: combining unanticipated ICU admissions and mortality for improved risk prediction
ObjectiveThis paper presents a comprehensive analysis of perioperative patient deterioration by develo** predictive models that evaluate...
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Factors affecting radiation dose, radiation exposure time and procedural time in arterial embolization for active hemorrhage
PurposeTo evaluate patient and procedure-related factors contributing to the radiation dose, cumulative fluoroscopy time (CFT), and procedural time...
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Outcomes following endorectal pull-through for Hirschsprung disease: a retrospective study
PurposeTo share our experience in the surgical management of patients with Hirschsprung disease (HD) using the trans-anal endorectal pull-through...
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Sleep disturbances in hospitalized children: a wake-up call
Although sleep is essential for (recovery of) health, it is adversely affected by hospitalization, due to disease discomfort, environmental noise,...
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Abdominal wall muscle weakness outcomes after split abdominal flap repair of large congenital diaphragmatic hernias in newborn
PurposeSplit abdominal wall muscle flap (SAWMF) is a technique to repair large defects in congenital diaphragmatic hernia (CDH). A possible objection...
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SARS-CoV-2 in Mozambican primary school-aged children at Maputo City and Province: a cross-sectional study from a low-income country
BackgroundSeroprevalence studies provide information on the true extent of infection and capture demographic and geographic differences, indicating...
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Paracetamol overdose causing acute kidney injury without hepatotoxicity: a case report
BackgroundParacetamol is a widely used analgesic and antipyretic. Paracetamol-induced hepatotoxicity is well known, but nephrotoxicity without...
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Impact of a family support intervention on hospitalization costs and hospital readmissions among ICU patients at high risk of death or severe functional impairment
BackgroundPatients with advanced critical illness often receive more intensive treatment than they would choose for themselves, which contributes to...
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Social determinants of health and sepsis: a case-control study
PurposeWe aimed to identify whether social determinants of health (SDoH) are associated with the development of sepsis and assess the differences...
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Malnutrition management in children with chronic kidney disease
Chronic kidney disease (CKD) encompasses diverse conditions such as congenital anomalies, glomerulonephritis, and hereditary nephropathies,...
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Acetaminophen induced high anion gap metabolic acidosis: a potentially under-recognized consequence from a common medication
While metabolic acidosis is one of the most common complications in patients with chronic kidney disease (CKD), there are several uncommon etiologies...
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The wolf in sheep’s clothing: vasovagal syncope in acute aortic dissection
BackgroundThe presentation of acute aortic dissection can pose a challenge for emergency physicians, as it may occur without pain. Atypical...