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Prevalence and correlates of common mental disorders among participants of the Uganda Genome Resource: Opportunities for psychiatric genetics research
Genetics research has potential to alleviate the burden of mental disorders in low- and middle-income-countries through identification of new...
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Religious Belief Among Women in Australia: Characteristics and Role in Influencing Children’s Health-Related Quality of Life and Lifestyle
Religiosity can be an important factor in women’s health-related behaviour, attitudes, and decision-making. Evidence however, regarding the...
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PET imaging of neuroinflammation: any credible alternatives to TSPO yet?
Over the last decades, the role of neuroinflammation in neuropsychiatric conditions has attracted an exponentially growing interest. A key driver for...
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Evaluating a National Academic Mentorship Program to Grow the Next Generation of Gender-based Violence Intervention and Prevention (VIP) Researchers
PurposeThe personal, economic, and societal costs and consequences of gender-based violence are significant. Although much violence intervention and...
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A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior
The single nucleotide polymorphism rs13166360, causing a substitution of valine (Val) 147 to leucine (Leu) in the adenylyl cyclase 2 (ADCY2), has...
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Microstructural characterization of multiple sclerosis lesion phenotypes using multiparametric longitudinal analysis
Background and objectivesIn multiple sclerosis (MS), slowly expanding lesions were shown to be associated with worse disability and prognosis. Their...
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Patients with complex and very-early-onset ATL1-related spastic paraplegia offer insights on genotype/phenotype correlations and support for autosomal recessive forms of SPG3A
Spastic paraplegia type 3A (SPG3A) is the second most common form of hereditary spastic paraplegia (HSP). This autosomal-dominant-inherited motor...
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School modality, race and ethnicity, and mental health of U.S. adolescents during the COVID-19 pandemic
BackgroundWhile minoritized ethnoracial groups were most likely to be in online learning during the COVID-19 pandemic, the impact of these...
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Esketamine in depression: putative biomarkers from clinical research
The discovery of racemic ( R , S )-ketamine as a rapid-acting antidepressant and the subsequent FDA approval of its ( S )-enantiomer, esketamine, for...
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“So Just with every Facet, Every Side of this Journey, They Have Somebody Walking alongside with Them”: Practitioners’ Perspectives of the Lethality Assessment Program as a Collaborative Model
PurposeAscriticism of the criminalization of domestic violence (DV) has gained momentum, programs such as the Lethality Assessment Program (LAP)...
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Application of GWAS summary data and drug-induced gene expression profiles of neural progenitor cells in psychiatric drug prioritization analysis
Common psychiatric disorders constitute one of the most substantial healthcare burdens worldwide. However, drug development in psychiatry remains...
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Surgical strategy in treatment of metopic synostosis in a single centre experience: technical note and quantitative analysis of the outcomes
PurposeTrigonocephaly is the most common craniosynostosis involving orbits. Although some degree of agreement has been reached regarding surgical...
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Astrocytic Neuroligin-3 influences gene expression and social behavior, but is dispensable for synapse number
Neuroligin-3 ( Nlgn3 ) is an autism-associated cell-adhesion molecule that interacts with neurexins and is robustly expressed in both neurons and...
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Intake Characteristics as Predictors of Psychotherapy Outcome in a Practice Research Network in Argentina
There are few studies exploring intake diagnostic characteristics as predictors of change in integrative naturalistic settings. The aim of this study...
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Estrogen receptor beta signaling enhances extinction memory recall for heroin-conditioned cues in a sex- and region-specific manner
Return to use, or relapse, is a major challenge in the treatment of opioid use disorder (OUD). Relapse can be precipitated by several factors,...
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“Some Handle It in Ways Others See as Insane:” College Individuals’ Meaning-Making about their Motivations for Severe Unwanted Pursuit Behaviors
PurposePost-relationship pursuit can range from normative to problematic, including stalking. While there are some theories and research about...
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Automated classification of brain MRI reports using fine-tuned large language models
PurposeThis study aimed to investigate the efficacy of fine-tuned large language models (LLM) in classifying brain MRI reports into pretreatment,...
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Trauma, adversity, and biological aging: behavioral mechanisms relevant to treatment and theory
Although stress and adversity are largely universal experiences, people exposed to greater hardship are at increased risk for negative health...
