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PET imaging of neuroinflammation: any credible alternatives to TSPO yet?
Over the last decades, the role of neuroinflammation in neuropsychiatric conditions has attracted an exponentially growing interest. A key driver for...
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A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior
The single nucleotide polymorphism rs13166360, causing a substitution of valine (Val) 147 to leucine (Leu) in the adenylyl cyclase 2 (ADCY2), has...
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Multimodal training protocols on unstable rather than stable surfaces better improve dynamic balance ability in older adults
BackgroundThere has been growing interest in using unstable devices in training protocols. This study aimed to assess the effectiveness of two...
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Estrogen receptor beta signaling enhances extinction memory recall for heroin-conditioned cues in a sex- and region-specific manner
Return to use, or relapse, is a major challenge in the treatment of opioid use disorder (OUD). Relapse can be precipitated by several factors,...
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Trauma, adversity, and biological aging: behavioral mechanisms relevant to treatment and theory
Although stress and adversity are largely universal experiences, people exposed to greater hardship are at increased risk for negative health...
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Sleep profiles of different psychiatric traits
Disturbed sleep comes in many forms. While the key role of sleep in mental health is undisputed, our understanding of the type of slee** problems...
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Leveraging continuous glucose monitoring as a catalyst for behaviour change: a sco** review
BackgroundAmidst the escalating prevalence of glucose-related chronic diseases, the advancements, potential uses, and growing accessibility of...
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Behaviour change interventions to improve physical activity in adults: a systematic review of economic evaluations
BackgroundBehaviour change interventions can result in lasting improvements in physical activity (PA). A broad implementation of behaviour change...
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Serum dysregulation of serine and glycine metabolism as predictive biomarker for cognitive decline in frail elderly subjects
Frailty is a common age-related clinical syndrome characterized by a decline in the function of multiple organ systems, increased vulnerability to...
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DNA methylation profiles of cancer-related fatigue associated with markers of inflammation and immunometabolism
Cancer patients are commonly affected by fatigue. Herein, we sought to examine epigenetic modifications (i.e., DNA methylation) related to fatigue in...
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Exploring the complex associations among risks of malnutrition, sarcopenia, and frailty in community-dwelling older adults
BackgroundMalnutrition, sarcopenia, and frailty are age-related conditions that are associated with multiple health-related negative outcomes....
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Modulation of dlPFC function and decision-making capacity by repetitive transcranial magnetic stimulation in methamphetamine use disorder
This study explores the impact of repetitive transcranial magnetic stimulation (rTMS) on decision-making capabilities in individuals with...
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The role of playgrounds in promoting children’s health – a sco** review
BackgroundActive outdoor play is important for children’s health and development, and playgrounds provide good places for play. However, the...
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Effect of transcranial direct current stimulation with concurrent cognitive performance targeting posterior parietal cortex vs prefrontal cortex on working memory in schizophrenia: a randomized clinical trial
Working memory deficits are linked to irregularities in the dorsolateral prefrontal cortex (DLPFC) and the posterior parietal cortex (PPC) in...
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Improving student diet and food security in higher education using participatory and co-creation approaches: a systematic review
BackgroundHigher education students are an important target group for public health nutrition interventions. When designing tailored and contextually...
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The risks for major psychiatric disorders in the siblings of probands with major depressive disorder
Using a case-controlled study including siblings of major depression (MD) and control probands, born 1970–1990 and followed through 2018, we sought...
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Thalamocortical functional connectivity and rapid antidepressant and antisuicidal effects of low-dose ketamine infusion among patients with treatment-resistant depression
Previous studies have shown an association between the thalamocortical dysconnectivity and treatment-resistant depression (TRD). Whether a single...
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HIV in Eswatini: Climate Change Impacts and Adaptation Strategies
Purpose of ReviewThis review assessed the impact of climate change on HIV transmission and HIV care of children and adults in Eswatini, and what...
