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Ginsenoside Rb1 reduces oxidative/carbonyl stress damage and dysfunction of RyR2 in the heart of streptozotocin-induced diabetic rats
BackgroundOxidative stress may contribute to cardiac ryanodine receptor (RyR2) dysfunction in diabetic cardiomyopathy. Ginsenoside Rb1 (Rb1) is a...
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Cholesterol Lowering in Older Adults: Should We Wait for Further Evidence?
Purpose of ReviewCurrent guidelines for primary and secondary prevention of cardiovascular events in adults up to age 75 years are well-established....
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A Potential Role for MAGI-1 in the Bi-Directional Relationship Between Major Depressive Disorder and Cardiovascular Disease
Purpose of ReviewMajor Depressive Disorder (MDD) is characterized by persistent symptoms such as fatigue, loss of interest in activities, feelings of...
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Gefäßchirurgie in Deutschland: Eine Umfrage und Datenbankanalyse der Deutschen Gesellschaft für Gefäßchirurgie und Gefäßmedizin
BackgroundThe German hospital system faces comprehensive. An insight into local structures and performance data may help to guide future...
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Paracetamol overdose causing acute kidney injury without hepatotoxicity: a case report
BackgroundParacetamol is a widely used analgesic and antipyretic. Paracetamol-induced hepatotoxicity is well known, but nephrotoxicity without...
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Pharmacotherapy and cardiovascular challenges: a case report of olverembatinib-induced myocardial infarction with non-obstructive coronary arteries
The anticancer drug of tyrosine kinase-inhibitors (TKIs) has significantly improved the prognosis of patients with specific leukemia but has also...
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The wolf in sheep’s clothing: vasovagal syncope in acute aortic dissection
BackgroundThe presentation of acute aortic dissection can pose a challenge for emergency physicians, as it may occur without pain. Atypical...
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Increased risk of develo** cerebro-cardiovascular diseases in police officers: a nationwide retrospective cohort study
BackgroundPolice officers face an increased risk of develo** cerebro-cardiovascular diseases (CVD). However, current literature lacks...
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Monoklonale Gammopathie renaler Signifikanz (MGRS)
Monoclonal gammopathy of renal significance (MGRS) is a heterogeneous group of diseases in which there is a pathogenetic link between the detection...
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Pulmonary embolism in patients with chronic coronary syndrome masquerading as acute coronary syndrome: a case report and literature review
BackgroundPulmonary embolisms (PEs) exhibit clinical features similar to those of acute coronary syndrome (ACS), including electrocardiographic...
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Electrocardiographic tracking of left ventricular hypertrophy in hypertension: incidence and prognostic outcomes from the SPRINT trial
BackgroundThis study explores the impact of intensive blood pressure (BP) control on left ventricular hypertrophy (LVH) incidence and evaluates the...
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Comparing blood pressure measurements between sitting in chairs and sitting on the floor
BackgroundThe current standard approach to measuring home blood pressure (BP) involves taking measurements while sitting in a chair. In cultures...
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Nonpharmacological interventions on glycated haemoglobin in youth with type 1 diabetes: a Bayesian network meta-analysis
The available evidence on the impact of specific non-pharmacological interventions on glycaemic control is currently limited. Consequently, there is...
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Recurrence in isolated distal DVT after anticoagulation: a systematic review and meta-analysis of axial and muscular venous thrombosis
ObjectiveTo identify recurrent venous thromboembolism (VTE) after discontinuation of anticoagulation in patients with isolated distal deep vein...
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Onkologische Herausforderungen bei Patienten mit chronischem Nierenversagen an der Dialyse und nach Transplantation
Tumor diseases occur more frequently both in dialysis patients and after kidney transplantation compared to the general population. As oncological...
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Nonlinear association between atherogenic index of plasma and type 2 diabetes mellitus in overweight and obesity patients: evidence from Chinese medical examination data
BackgroundThe atherogenic index of plasma (AIP) is closely associated with the onset of diabetes, with obesity being a significant risk factor for...
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Impaired GK-GKRP interaction rather than direct GK activation worsens lipid profiles and contributes to long-term complications: a Mendelian randomization study
BackgroundGlucokinase (GK) plays a key role in glucose metabolism. In the liver, GK is regulated by GK regulatory protein (GKRP) with nuclear...
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Roles of non-coding RNA in diabetic cardiomyopathy
In recent years, the incidence of diabetes has been increasing rapidly, posing a serious threat to human health. Diabetic cardiomyopathy (DCM) is...
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