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Efficacy and Safety of Salvage-line Nivolumab Monotherapy for Advanced Esophageal Squamous Cell Carcinoma: Comparison of 240 mg Versus 480 mg Doses
BackgroundNivolumab monotherapy is the standard second-line treatment for advanced esophageal squamous cell carcinoma (ESCC) after failure of...
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Assessing the suitability of video-assisted anal fistula treatment for obese patients compared to conventional surgery: a question worth investigating
Background and aimsVideo-assisted anal fistula treatment (VAAFT) is an innovative surgical approach enabling the direct visualization of the fistula...
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Ethical Implications of Artificial Intelligence in Gastroenterology: The Co-pilot or the Captain?
Though artificial intelligence (AI) is being widely implemented in gastroenterology (GI) and hepatology and has the potential to be paradigm shifting...
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Readability of online patient education material for foregut surgery
IntroductionHealth literacy is the ability of individuals to use basic health information and services to make well-informed decisions. Low health...
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Immunosuppression in adult liver transplant recipients: a 2024 update from the Italian Liver Transplant Working Group
PurposeAdvances in surgical procedures and immunosuppressive therapies have considerably improved the outcomes of patients who have undergone liver...
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Comparative evaluation of reproductive organ-preserving versus standard radical cystectomy in female: a meta-analysis and systematic review of perioperative, oncological, and functional outcomes
BackgroundTo evaluate the perioperative, oncological, and functional outcomes of reproductive organ-preserving radical cystectomy (ROPRC) compared to...
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NAFLD and MAFLD independently increase the risk of major adverse cardiovascular events (MACE): a 20-year longitudinal follow-up study from regional Australia
Background and aimsThe association between fatty liver disease (FLD) and cardiovascular disease (CVD) in an Australian context has yet to be defined....
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Single center assessment of the role of Oakland score among patients admitted for acute lower gastrointestinal bleeding
Background/ObjectivesThe Oakland score was developed to predict safe discharge in patients who present to the emergency department with lower...
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Evidence for Intermittent Theta Burst Transcranial Magnetic Stimulation for Dysphagia after Stroke: A Systematic Review and Meta-analysis
Dysphagia is the most common serious complication after stroke, with an incidence of about 37–78%, which seriously affects the independence of...
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Gastric band removal: mind the arterial anastomoses!
Bariatric surgery may sometimes be challenging and may lead to severe complications. Surgical re-intervention in such cases is not the preferred...
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Impact of hypoalbuminemia on outcomes following pancreaticoduodenectomy: a NSQIP retrospective cohort analysis of 25,848 patients
BackgroundEfforts to preoperatively risk stratify and optimize patients before pancreaticoduodenectomy continue to improve outcomes. This study aims...
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DDS–SIRC Cooperative Conferences Feel the Burn: RFA for Chronic Radiation Proctitis
Chronic radiation proctitis, although relatively rare, can be the source of severe comorbidity in patients who had undergone prior radiotherapy for...
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Transverse versus longitudinal mucosal incision during POEM for esophageal motility disorders: a randomized trial
BackgroundLongitudinal incision is the commonly used incision for entry into the submucosal space during peroral endoscopic myotomy (POEM) for...
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Safety and efficacy of robotic anti-reflux surgery in geriatric patients: a comparative analysis
IntroductionAs our population ages, older adults are being considered for anti-reflux surgery (ARS). Geriatric patients typically have heightened...
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Laparoscopic caudate lobe resections: How I do it: tips and pitfalls (with video)
BackgroundThe caudate lobe (S1) of the liver, due to its deep central position, presents a formidable challenge for laparoscopic resection....
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LapBot-Safe Chole: validation of an artificial intelligence-powered mobile game app to teach safe cholecystectomy
BackgroundGaming can serve as an educational tool to allow trainees to practice surgical decision-making in a low-stakes environment. LapBot is a...
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Implementing a no-drain policy for extraperitoneal colorectal anastomosis in a real-life setting: analysis of outcomes and surgeons’ adherence
AimRecent evidence has questioned the usefulness of anastomotic drain (AD) after low anterior resection (LAR). However, the implementation and...
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Quantitative and qualitative evaluation of high-quality hepatobiliary phase imaging with shortened timing and utility in patients with compromised liver function
PurposeTo compare high flip angle (FA) hepatobiliary-phase (hHBP) imaging with variable time intervals to conventional HBP (cHBP) to assess the...
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Indomethacin Does Not Reduce Post-ERCP Pancreatitis in High-Risk Patients Receiving Pancreatic Stenting
BackgroundRectal indomethacin reduces pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP). However, there is insufficient...