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Benzodiazepine use in relation to long-term dementia risk and imaging markers of neurodegeneration: a population-based study
BackgroundBenzodiazepine use is common, particularly in older adults. Benzodiazepines have well-established acute adverse effects on cognition, but...
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Inappropriate treatment of pulmonary aspergillosis caused by Aspergillus flavus in susceptible pediatric patients: a case series
BackgroundPulmonary aspergillosis is a prevalent opportunistic fungal infection that can lead to mortality in pediatric patients with underlying...
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Neuroimmune crosstalk
Cardiovascular diseases are the leading cause of death worldwide. Pathophysiologically, metabolic and inflammatory processes contribute substantially...
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SMS-based interventions for improving child and adolescent vaccine coverage and timeliness: a systematic review
BackgroundThe aim of this review was to investigate the impact of short message service (SMS)-based interventions on childhood and adolescent vaccine...
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Associations between accelerometer-measured physical activity and sedentary behaviour with physical function among older women: a cross-sectional study
BackgroundThis study aimed to investigate the relationships between accelerometer-measured physical activity (PA) and sedentary behaviour (SB) with...
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Impact of USMLE Step 1 transition to pass/fail scoring system on medical students’ anxiety, sleep quality, and burnout
IntroductionOriginally designed to evaluate the application of foundational scientific knowledge in clinical contexts, the United States Medical...
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miR-146a and miR-155 as promising biomarkers for prognosis and diagnosis of multiple sclerosis: systematic review
BackgroundSmall RNA molecules known as microRNAs (miRNAs) regulate gene expression during the post-translational steps. miRNAs are essential for many...
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Long-term comparison of renal and metabolic outcomes after sodium–glucose co-transporter 2 inhibitor or glucagon-like peptide-1 receptor agonist therapy in type 2 diabetes
BackgroundRenal outcomes in patients with type 2 diabetes following treatment with sodium–glucose co-transporter-2 inhibitors (SGLT2is) or...
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Role of ZNF334 in cervical cancer: implications for EMT reversal and tumor suppression
Zinc-finger proteins are involved in many biological processes. However, the role of Zinc-finger protein 334 (ZNF334) in cervical cancer remains...
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Effect of norepinephrine and phenylephrine on prothrombotic response in patients undergoing cesarean section under spinal anesthesia: protocol for a randomized, double-blind, controlled study
BackgroundNorepinephrine and phenylephrine are commonly used vasoactive drugs to treat hypotension during the perioperative period. The increased...
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Liver autotransplantation and atrial reconstruction on a patient with multiorgan alveolar echinococcosis: a case report
BackgroundAlveolar echinococcosis (AE) primarily affects the liver and potentially spreads to other organs. Managing recurrent AE poses significant...
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The importance of sleep for the develo** brain
Purpose of reviewThis paper summarizes recent research regarding the possible contribution of sleep to brain development. Major milestones in brain...
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Prevention of Rheumatoid Arthritis in At-Risk Individuals: Current Status and Future Prospects
Early intervention has been the cornerstone of improving outcomes in patients with rheumatoid arthritis. Over the past decade, the boundaries have...
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Effect of esketamine combined with dexmedetomidine on delirium in sedation for mechanically ventilated ICU patients: protocol for a nested substudy within a randomized controlled trial
BackgroundUse of sedatives and analgesics is associated with the occurrence of delirium in critically ill patients receiving mechanical ventilation....
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Ethnicity and outcomes for patients with gastrointestinal disorders attending an emergency department serving a multi-ethnic population
BackgroundEthnic inequalities in acute health acute care are not well researched. We examined how attendee ethnicity influenced outcomes of emergency...
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Rising socioeconomic disparities in childhood overweight and obesity in Belgium
BackgroundChildhood overweight, especially obesity, significantly impacts children’s health and poses an increased risk of adult-onset diseases. This...
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Cai’s herbal tea enhances mitochondrial autophagy of type 1 diabetic mellitus β cells through the AMPK/mTOR pathway and alleviates inflammatory response
BackgroundThis study investigates the therapeutic mechanisms of Cai’s Herbal Tea in Type 1 Diabetes Mellitus (T1DM) mice, focusing on its effects on...
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Estimated global and regional economic burden of genital herpes simplex virus infection among 15–49 year-olds in 2016
BackgroundGlobally, herpes simplex virus (HSV)-2 and -1 infections contribute to a large disease burden, but their full economic consequences remain...
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Cognitive behavioral therapy for the treatment of insomnia in patients with cardiovascular diseases: a meta-analysis with GRADE analysis
Insomnia, as a difficulty in initiating and maintaining sleep, coupled with cardiovascular diseases (CVDs) increase the risk of aggravate daytime...
