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Mathematics

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Showing 1-6 of 6 results

  1. Drug target ontology to classify and integrate drug discovery data

    Background

    One of the most successful approaches to develop new small molecule therapeutics has been to start from a validated druggable protein...

    Yu Lin, Saurabh Mehta, ... Stephan C. Schürer in Journal of Biomedical Semantics
    Article Open access 09 November 2017

  2. “Big Data and Dynamics”—The Mathematical Toolkit Towards Personalized Medicine

    Predictive models and simulations addressing the individual progression of diseases are crucial for the optimization of diagnostic tools and...
    Lisa Turnhoff, Nina Kusch, Andreas Schuppert in Patterns of Dynamics
    Conference paper 2017

  3. Reconstructing a Genetic Network from Gene Perturbations in Secretory Pathway of Cancer Cell Lines

    Gene perturbation studies play an important role in the reconstruction of genetic networks and in determining the influence of genes on each other...
    Marina Piccirillo, Kumar Parijat Tripathi, ... Mario Rosario Guarracino in Dynamics of Mathematical Models in Biology
    Chapter 2016

  4. Dissecting the Functions of the Secretory Pathway by Transcriptional Profiling

    The secretory pathway is responsible for biosynthesis, processing, sorting, and delivery of variety of proteins encoded in the human genome to their...
    Sonali Gopichand Chavan, Kumar Parijat Tripathi, ... Seetharaman Parashuraman in Dynamics of Mathematical Models in Biology
    Chapter 2016

  5. Evolving BioAssay Ontology (BAO): modularization, integration and applications

    The lack of established standards to describe and annotate biological assays and screening outcomes in the domain of drug and chemical probe...

    Saminda Abeyruwan, Uma D Vempati, ... Stephan C Schürer in Journal of Biomedical Semantics
    Article Open access 03 June 2014

  6. Selected papers from the 16th Annual Bio-Ontologies Special Interest Group Meeting

    Over the 16 years, the Bio-Ontologies SIG at ISMB has provided a forum for vibrant discussions of the latest and most innovative advances in the...

    Larisa N Soldatova, Philippe Rocca-Serra, ... Nigam H Shah in Journal of Biomedical Semantics
    Article Open access 03 June 2014
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