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Blood Coagulation
This chapter is devoted to the description and modeling of the process of blood coagulation which is crucial for life and is the result of an...
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Towards a more molecular taxonomy of disease
BackgroundDisease taxonomies have been designed for many applications, but they tend not to fully incorporate the growing amount of molecular-level...
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Balance Laws
We adopt the view that growth is modeled by a multiplicative decomposition of the deformation gradient from an unstressed configuration to the...
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Building a model for disease classification integration in oncology, an approach based on the national cancer institute thesaurus
BackgroundIdentifying incident cancer cases within a population remains essential for scientific research in oncology. Data produced within...
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Development of an Ontology for Periodontitis
BackgroundIn the clinical dentists and periodontal researchers’ community, there is an obvious demand for a systems model capable of linking the...
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NCBO Ontology Recommender 2.0: an enhanced approach for biomedical ontology recommendation
BackgroundOntologies and controlled terminologies have become increasingly important in biomedical research. Researchers use ontologies to annotate...
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On the Origin of Patterns
This chapter elaborates on the origin of patterns in nature. pattern formation origin of The...
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PhenoImageShare: an image annotation and query infrastructure
BackgroundHigh throughput imaging is now available to many groups and it is possible to generate a large quantity of high quality images quickly....
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Other Distances
In this chapter we group together distances and distance paradigms which do not fit in the previous chapters, being either too practical (as in...
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Response of an oscillatory differential delay equation to a single stimulus
Here we analytically examine the response of a limit cycle solution to a simple differential delay equation to a single pulse perturbation of the...
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KneeTex: an ontology–driven system for information extraction from MRI reports
BackgroundIn the realm of knee pathology, magnetic resonance imaging (MRI) has the advantage of visualising all structures within the knee joint,...
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Hemorheology and Hemodynamics
In this first approach to the subject we start describing a few basic facts about blood composition and about the circulatory system. Such notions...
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Automated concept and relationship extraction for the semi-automated ontology management (SEAM) system
BackgroundWe develop medical-specialty specific ontologies that contain the settled science and common term usage. We leverage current practices in...
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Development and validation of a classification approach for extracting severity automatically from electronic health records
BackgroundElectronic Health Records (EHRs) contain a wealth of information useful for studying clinical phenotype-genotype relationships. Severity is...
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Global Changes in the Connectome in Autism Spectrum Disorders
There is an increasing interest in connectomics as means to characterize the brain both in healthy controls and in disease. Connectomics strongly...
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Understanding, Treating and Avoiding Hematological Disease: Better Medicine Through Mathematics?
This paper traces the experimental, clinical and mathematical modeling efforts to understand a periodic hematological disease—cyclical neutropenia....
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Semantic interestingness measures for discovering association rules in the skeletal dysplasia domain
BackgroundLately, ontologies have become a fundamental building block in the process of formalising and storing complex biomedical information. With...
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Wrocław
NOVEMBER 18, 1945. I left by bus for Wrocław on the morning of November 14. A Jewish woman with a stentorian voice—typical of a certain type of...
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Manifolds in a Theory of Microstructures
A synopsis, broadly based on contributions by Capriz and co-workers, is presented of a model for a body with microstructure that employs the...
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The influence of disease categories on gene candidate predictions from model organism phenotypes
BackgroundThe molecular etiology is still to be identified for about half of the currently described Mendelian diseases in humans, thereby hindering...
