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Percolation in Biological Systems
Most biological systems are so complex that they preclude any reasonable description in terms of the exact interactions among their fundamental...
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Sublime Experience: New Strategies for Measuring the Aesthetic Impact of the Sublime
In aesthetics’ history, sublime is a very controversial category. It can be defined as a feeling consisting contemporarily of pleasure and...
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Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development
Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages...
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Stochastic Point Processes and Random Trees
Models of stochastic point processes are basic models of random sets with a rather simple geometry. The archetype model is the Poisson point process,...
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CUILESS2016: a clinical corpus applying compositional normalization of text mentions
BackgroundTraditionally text mention normalization corpora have normalized concepts to single ontology identifiers (“pre-coordinated concepts”). Less...
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Oscillations in a white blood cell production model with multiple differentiation stages
In this work we prove occurrence of a super-critical Hopf bifurcation in a model of white blood cell formation structured by three maturation stages....
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Digital Social Science
The fascinated concerns with the AI and big data have been growing in these days. Over the past few years, a considerable number of industrial and...
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Numerical modelling of generalized Newtonian fluids in bypass tube
The following paper describes a numerical simulation of a complete bypass of a stenosed human artery. The considered geometry consists of the...
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Mechanics of Hydrocephalus
Hydrocephalus is a serious neurological disorder which was first described by Hippocrates (460–370 BC) as water on the brain. The disorder is...
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Modeling Strategies to Win the War Against Breast Cancer
This is the central part of the monograph. Mathematically, we have tried to model the present treatment methodologies for various forms of breast...
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Vitreous Pathology
The vitreous is involved in a wide variety of pathologies. The vitreoretinal interface is the site of adhesion between the posterior vitreous cortex...
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Structuring, reuse and analysis of electronic dental data using the Oral Health and Disease Ontology
BackgroundA key challenge for improving the quality of health care is to be able to use a common framework to work with patient information acquired...
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The Mystery of Plato’s Receptacle in the Timaeus Resolved
Plato, most unexpectedly, in the middle of the Timaeus (48e2-49a7) declares that the sensible bodies cannot be explained solely by their...
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Modelling collective cell migration: neural crest as a model paradigm
A huge variety of mathematical models have been used to investigate collective cell migration. The aim of this brief review is twofold: to present a...
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Using predicate and provenance information from a knowledge graph for drug efficacy screening
BackgroundBiomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They...
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The Mystery of Plato’s Receptacle in the Timaeus Resolved
Plato, most unexpectedly, in the middle of the Timaeus (48e2-49a7) declares that the sensible bodies cannot be explained solely by their...
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Blood and Cancer
In this chapter we will deal with the aspects which are specific to blood cancer, avoiding to broaden our analysis to the general area of modeling...
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Capturing domain knowledge from multiple sources: the rare bone disorders use case
BackgroundLately, ontologies have become a fundamental building block in the process of formalising and storing complex biomedical information. The...
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Normal and pathological dynamics of platelets in humans
We develop a mathematical model of platelet, megakaryocyte, and thrombopoietin dynamics in humans. We show that there is a single stationary solution...
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Disease Compass– a navigation system for disease knowledge based on ontology and linked data techniques
BackgroundMedical ontologies are expected to contribute to the effective use of medical information resources that store considerable amount of data....
