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A green light-enhanced cytosolic protein delivery platform based on BODIPY-protein interactions
Development of cytosolic protein delivery platforms brings new possibilities for various incurable diseases. Strategies based on polymer/protein...
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Electrochemical Biosensors for Nucleic Acids Detection
The highly sensitive and selective detection of nucleic acids in clinical samples is of great significance to the diagnosis and prognosis of...
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Responsive biomaterials: optimizing control of cancer immunotherapy
Immunotherapy has emerged as an eminent and effective modality in the treatment of cancer. However, current cancer immunotherapies lack spatial and...
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Photo-triggered nucleus targeting for cancer drug delivery
Here, we report a strategy to deliver drug nanoparticles into cells with nucleus-targeting ability under a spatiotemporal control. The nanoparticles...
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Engineering receptor-mediated transmembrane signaling in artificial and living cells
Living cells possess a variety of transmembrane signaling systems that receive chemical and physical cues from the environment and transduce this...
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A light-activatable antibiotic with high activation efficiency and uncompromised bactericidal potency in the activated state
AbstractAchieving activatable antibiotics represents one promising solution to tackle the occurrence of side effects, one major issue now plaguing...
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Polymeric biomaterial-inspired cell surface modulation for the development of novel anticancer therapeutics
Immune cell-based therapies are a rapidly emerging class of new medicines that directly treat and prevent targeted cancer. However multiple...
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Biomedical Applications of Green Nanomaterials
The unique physicochemical, optical, electrical, and biological characteristics of nanomaterials led to their extensive exploitation in biomedical...
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Impact of Stimuli-Responsive Biomaterials in Gynecological Cancer Therapy
Gynecological cancers, predominantly cervical, ovarian, uterine, and vaginal, are among the most challenging cancers to treat due to their complex...
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Biomedical Applications of Green Nanomaterials
The unique physicochemical, optical, electrical, and biological characteristics of nanomaterials led to their extensive exploitation in biomedical...
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Hydrogels for RNA delivery
RNA-based therapeutics have shown tremendous promise in disease intervention at the genetic level, and some have been approved for clinical use,...
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Photo-controlled release of paclitaxel and model drugs from RNA pyramids
Stimuli-responsive release of drugs from a nanocarrier in spatial-, temporal-, and dosage-controlled fashions is of great interest in the...
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Extracellular vesicle–matrix interactions
The extracellular matrix (ECM) harbours various signals to control cellular functions and the materiality of tissues. Most efforts to synthetically...
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Synthesis and Development of Platinum-Based Anticancer Drugs
This article describes the prime role of anticancer drugs based on platinum in clinical treatment, their limitations and side effects. The efforts to...
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Nanobiomaterials in Craniofacial Bone Regeneration
Reconstruction of oral and craniofacial bone defects has been a challenging issue for maxillofacial surgeons, periodontists, and scientists. The...
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Bioenzyme-based nanomedicines for enhanced cancer therapy
Bioenzymes that catalyze reactions within living systems show a great promise for cancer therapy, particularly when they are integrated with...
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Light-responsive charge-reversal nanovector for high-efficiency in vivo CRISPR/Cas9 gene editing with controllable location and time
Controllably and efficaciously localized CRISPR/Cas9 plasmids transfection plays an essential role in genetic editing associated with various key...
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Automated molecular-image cytometry and analysis in modern oncology
Diagnostic methods for initial diagnosis and patient stratification for treatment are key to modern oncology, but many challenges remain. In...
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Light hybrid micro/nano-robots: From propulsion to functional signals
Untethered motile micro/nanorobots (MNRs) that can operate in hard-to-reach small space and perform noninvasive tasks in cellular level hold bright...
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When mRNA meets gene editing
The critical challenge of gene therapy lies in delivering gene editing agents. Compared with DNA, while RNA is less stable and more accessible to...
