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Fe3+-binding transferrin nanovesicles encapsulating sorafenib induce ferroptosis in hepatocellular carcinoma
BackgroundFerroptosis, iron-dependent cell death, is an established mechanism for cancer suppression, particularly in hepatocellular carcinoma (HCC)....
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Magnetic transferrin nanoparticles (MTNs) assay as a novel isolation approach for exosomal biomarkers in neurological diseases
BackgroundBrain-derived exosomes released into the blood are considered a liquid biopsy to investigate the pathophysiological state, reflecting the...
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Transferrin-conjugated doxorubicin-loaded PLGA nanoparticles with pH-responsive behavior: a synergistic approach for cancer therapy
Doxorubicin (DOX) is an efficient chemotherapeutic agent widely used to treat different types of cancer; however, there is an inherent risk of...
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Dual-ratiometric magnetic resonance tunable nanoprobe with acidic-microenvironment-responsive property to enhance the visualization of early tumor pathological changes
The development of microenvironment-responsive nanoprobes has shown great promise for use in magnetic resonance imaging (MRI), with the advantage of...
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Preparation of transferrin-conjugated poly-ε-caprolactone nanoparticles and delivery of paclitaxel to treat glioblastoma across blood–brain barrier
The delivery of anticancer drug to the brain remains a major challenge due to the existence of blood–brain barrier (BBB). Receptor-mediated...
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A novel formulation of theranostic nanomedicine for targeting drug delivery to gastrointestinal tract cancer
BackgroundTheranostic nanomedicines contain a nanovehicle that has fluorescent properties and can be used for diagnostic, therapeutic and prognostic...
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Recent Developments in Quantum Dots Technologies as Effective Theranostic Tools Against Cancer
Cancer, being a condition of unhindered cell growth ultimately leading to the death of the patient, is very prominent in modern society. Despite all...
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Liposomal Delivery System
Liposomes are biodegradable and biocompatible lipid bilayer vesicles that are employed as potential carriers for the delivery of drugs to the desired...
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Selective cytotoxic effects of nitrogen-doped graphene coated mixed iron oxide nanoparticles on HepG2 as a new potential therapeutic approach
New selective therapeutics are needed for the treatment of hepatocellular carcinoma (HCC), the 7th most common cancer. In this study, we compared the...
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Carrier-free programmed spherical nucleic acid for effective ischemic stroke therapy via self-delivery antisense oligonucleotide
Antisense oligonucleotide (ASO) for anti-apoptosis is emerging as a highly promising therapeutic agents for ischemic stroke with complex pathological...
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Effect of acid-alkali treatment on serum protein adsorption and bacterial adhesion to porous titanium
Modification of the titanium (Ti) surface is widely known to influence biological reactions such as protein adsorption and bacterial adhesion in...
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Targeting of Drug Nanocarriers
Nanostructured drug delivery systems can be functionalized, through non-covalent interaction or mainly by covalent bonding, with ligands for...
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Nanoparticles for Brain Tumor Imaging and Therapy
Nanoparticles have emerged as promising tools in the field of brain tumor imaging and therapy, offering unprecedented opportunities for precise...
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Antiproliferative and Apoptosis Triggering Potential of Paclitaxel-Based Targeted-Lipid Nanoparticles with Enhanced Cellular Internalization by Transferrin Receptors—a Study in Leukemia Cells
Leukemia is a typical blood cancer that is characterized by the numerous duplication and proliferation of white blood cells. The main aim of this...
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Engineering nanomaterials for glioblastoma nanovaccination
Glioblastoma is a lethal brain cancer with treatment resistance stemming from its interactions with the surrounding microenvironment and obstacles...
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Gold nanoparticle-based drug nanocarriers as a targeted drug delivery system platform for cancer therapeutics: a systematic review
Cancer was the world’s second major cause of death. Several treatments were available, including chemotherapy, radiotherapy, immunotherapy, and...
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Targeted drug delivery in cancer using nanomaterials: advances and challenges
Cancer is considered the world’s deadliest disease, and its underlying pathology is intricate. Though cancer patients have had access to...
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Nanocarriers for Drug Delivery: General Characteristics
The escalating pace of disease transmission has prompted scientists to embark on innovative approaches to enhance the therapeutic efficacy of modern...
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Advancements in neurotherapeutics: nanoparticles overcoming the blood–brain barrier for precise CNS targeting
Overcoming the blood–brain barrier (BBB) remains a substantial challenge in CNS drug delivery. This review explores the potential of lipid-based...
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Targeted Nano-based Drug Delivery in Alzheimer's Disease and Dementia
Alzheimer's disease (AD), the utmost widespread neurodegenerative illness, contributes to an enormous and expanding healthcare burden and impairs...