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Glycyrrhetinic acid-decorated and docetaxel-loaded thermosensitive liposomes for combination therapy against hepatocellular carcinoma
This report focused on a novel nano-drug delivery system (GA-DTX-PVP/CuS-TSL) by combining glycyrrhetinic acid, copper sulfide nanoparticles, and...
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Synergistic anti-tumor therapy by a homotypic cell membrane-cloaked biomimetic nanocarrier with exceptionally potent activity against hepatic carcinoma
Hepatic carcinoma (HC) is the sixth most frequently occurring malignancies and the third leading cause of cancer death worldwide. Sepantronium...
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Biotin-modified Galactosylated Chitosan-gene Carrier in Hepatoma Cells Targeting Delivery
Our previous studies have successfully grafted biotin and galactose onto chitosan (CS) and synthesized biotin modified galactosylated chitosan...
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Glutathione-responsive mesoporous silica nanocarriers for chemo–photothermal–photodynamic therapy of cancer
A series of antitumor therapies such as chemotherapy, photothermal therapy, and photodynamic therapy have certain limitations when applied alone....
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NIR-Triggered and ROS-Boosted Nanoplatform for Enhanced Chemo/PDT/PTT Synergistic Therapy of Sorafenib in Hepatocellular Carcinoma
Although being the first-line treatment of advanced hepatocellular carcinoma (HCC), sorafenib (SOR) outcome is limited due to drug resistance and low...
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Design, synthesis, and characterization of glycyrrhetinic acid-mediated multifunctional liver-targeting polymeric carrier materials
The purpose of this study was to construct a glycyrrhetinic acid (GA)-mediated, breakable, intracellular, nanoscale drug-delivery carrier via amide...
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Two-photon excited luminescence of structural light enhancement in subwavelength SiO2 coating europium ion-doped paramagnetic gadolinium oxide nanoparticle and application for magnetic resonance imaging
BackgroundOxides of lanthanide rare-earth elements show great potential in the fields of imaging and therapeutics due to their unique electrical,...
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Construction of pH-responsive nanocarriers in combination with ferroptosis and chemotherapy for treatment of hepatocellular carcinoma
BackgroundChemotherapy is widely used to treat hepatocellular carcinoma (HCC). Although sorafenib (SO) is the only chemotherapy drug approved by FDA...
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Confined structure regulations of molybdenum oxides for efficient tumor photothermal therapy
Molybdenum oxide nanoparticles (NPs) with tunable plasmonic resonance in the near-infrared region display superior semiconducting features and...
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An Overview on Biological Activity of Benzimidazole Derivatives
Benzimidazole moiety plays a key role in variety of heterocyclic scaffolds which derive the biological functioning of essential molecules. Because of...
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RETRACTED ARTICLE: M1 Macrophage-Derived Exosomal MicroRNA-326 Suppresses Hepatocellular Carcinoma Cell Progression Via Mediating NF-κB Signaling Pathway
Accumulating evidence has shown that microRNA (miR) derived from M1 macrophage-derived exosomes can regulate the progression of hepatocellular...
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Novel nanoparticle CS-C60-Fe3O4 magnetically induces tissue-specific aggregation and enhances thermal ablation of hepatocellular carcinoma
Metallofullerenes are an important type of metallic nanomaterial with promising applications in several medical fields. Thermal ablation, including...
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Quantum Dots Nanocomposites Bioimaging Probes
Quantum dots nanocomposites (QDNCs) are highly fascinating nanomaterials for bioimaging application due to their distinctive optical properties. By...
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Elite nanomaterials in cancer detection and therapy
The development of nanotechnology has completely changed doctor’s perceptions of current cancer treatments. Nanotherapeutics may replace conventional...
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Quantum Dots Based Composites for Diagnostics
In recent years, quantum dots (QDs) have emerged as a promising nanomaterial with the potential to revolutionize diagnostic applications due to their...
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Pharmaceutical Application of Bio-actives from Alstonia Genus: Current Findings and Future Directions
Genus Alstonia is comprised of around 155 species throughout the world. Phytochemical screening of Alstonia genus has demonstrated the presence of...
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Zinc Oxide as a Multifunctional Material: From Biomedical Applications to Energy Conversion and Electrochemical Sensing
Zinc oxide (ZnO) is a very attractive material which has received growing attention in the academic and technological areas. This metal oxide shows...
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Molecularly imprinted polymers (MIPs): emerging biomaterials for cancer theragnostic applications
Cancer is a disease caused by abnormal cell growth that spreads through other parts of the body and threatens life by destroying healthy tissues....
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Carbon Nanotropes: Potential Nanomaterials for Drug Delivery and Biomedical Applications
Carbon nanotropes, fullerene, carbon nanotubes, and graphene have gained extensive attention due to their robust nature, ultrathin structure, high...