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Improve the cytotoxic effects of megavoltage radiation treatment by Fe3O4@Cus–PEG nanoparticles as a novel radiosensitizer in colorectal cancer cells
BackgroundTo enhance the performance of radiotherapy, emerging nanoparticles that can professionally enhance X-ray irradiation to destruct cancer...
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Gold Nanoparticles Enhancing Generation of ROS for Cs-137 Radiotherapy
Radiotherapy is an important modality for the treatment of cancer, e.g., X-ray, Cs-137 γ -ray (peak energy: 662 keV). An important therapy pathway of...
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Autophagy inhibitor-loaded mesoporous AgNPs@SiO2 nanoplatform for synergistically enhanced glioma radiotherapy
Our previous studies demonstrated that silver nanoparticles (AgNPs) could be used as a potential radio-sensitizer for glioma radiotherapy...
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Hybrid transcytosis nanopomegranates for sensitizing breast cancer radiotherapy in deep tumor tissue
As a standard cancer treatment method, radiotherapy (RT) has cured or alleviated over half cancer bearing patients worldwide more than 100 years....
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Theranostic RGD@Fe3O4-Au/Gd NPs for the targeted radiotherapy and MR imaging of breast cancer
BackgroundAs a radiosensitizing agent in magnetic resonance imaging (MRI), gadolinium is disadvantageous in that it confers a rather high toxicity...
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Enhanced radiosensitivity and chemoradiation efficacy in nasopharyngeal carcinoma via a dual-targeted SPION@polymer hybrid nanosensitizer
Cisplatin-based nanoparticles show good potential in enhancing the effect of nasopharynx carcinoma (NPC) therapy but are still limited by their low...
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Mesoporous radiosensitized nanoprobe for enhanced NIR-II photoacoustic imaging-guided accurate radio-chemotherapy
Oxygen deficiency is a major obstacle to hypoxic-related cancer theranostics, and develo** the oxygen production nanoplatforms received the...
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Inhibiting PI3K/AKT/mTOR signaling by metal-organic frameworks for overcoming multiple drug resistance in chemoradiotherapy
Angiogenesis in the tumor microenvironment is the main cause for the insensitivity of tumor cells to chemoradiotherapy. Strategies for increasing the...
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SN38-loaded nanomedicine mediates chemo-radiotherapy against CD44-expressing cancer growth
BackgroundChemo-radiotherapy is the combined chemotherapy and radiotherapy on tumor treatment to obtain the local radiosensitization and local...
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Biological modeling of gadolinium-based nanoparticles radio-enhancement for kilovoltage photons: a Monte Carlo study
BackgroundGadolinium-based nanoparticles (GdNPs) are clinically used agents to increase the radiosensitivity of tumor cells. However, studies on the...
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Recent Progress of Gold Nanomaterials in Cancer Therapy
In radiotherapy, ionizing radiation causes deoxyribonucleic acid (DNA) damage in cancer cells, so that the cancer can be controlled by terminating...
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Radiosensitizers in Radiation-Induced Cancer Therapy
Radiation therapy (RT) has established as a very auspicious tool to tackle cancer, but its efficacy has encountered with some challenges. As we all...
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Dual enhancement in the radiosensitivity of prostate cancer through nanoparticles and chemotherapeutics
BackgroundRadiotherapy (RT) is an essential component in the treatment regimens for many cancer patients. However, the dose escalation required to...
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ROS-Based Cancer Radiotherapy
Reactive oxygen species (ROS) in cancer cells play a crucial role in metabolic reprogramming, altering tumor microenvironment, regulating cell death,...
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Emerging Nanomaterials as Radio-Sensitizer in Radiotherapy
Radiotherapy has been involved in treating 50% of the cancer patients in the world and is based on the direct energy deposition into tumor tissues....
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Tuning the Toxicity of Reactive Oxygen Species into Advanced Tumor Therapy
The biological functions and toxic effects of reactive oxygen species (ROS) are generally entangled. A large amount of ROS may cause oxidative damage...
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Recent Progress of Gold Nanomaterials in Cancer Therapy
In radiotherapy, ionizing radiation causes deoxyribonucleic acid (DNA) damage in cancer cells, so that the cancer can be controlled by terminating...
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Dual activated NIR-II fluorescence and photoacoustic imaging-guided cancer chemo-radiotherapy using hybrid plasmonic-fluorescent assemblies
Multimodal imaging in the second near-infrared window (NIR-II) guided cancer therapy is a highly precise and efficient cancer theranostic strategy....
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Liquid Metal Chemical Reaction
Liquid metals have attracted great attention among different areas. The unique combination of metallic and liquid properties distinguishes liquid...
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Enhancement of radiation response of breast cancer cells through the incorporation of Bi2S3 nanorods
The aim of this work was to develop nanomaterials that can be used as sensitizers in radiotherapy treatment. The synthesis of bismuth sulfide (Bi 2 S 3 )...
