Search
Search Results
-
Entropy-driven strand displacement reaction for ultrasensitive detection of circulating tumor DNA based on upconversion and Fe3O4 nanocrystals
Early detection of cancer biomarkers applied in real-time disease diagnosis and therapies can increase the survival rate of patients. Circulating...
-
Rigidity-dependent formation process of DNA supramolecular hydrogels
A DNA building block with tunable rigidity was constructed, and the corresponding hydrogel formation process was investigated accordingly. A high...
-
Locked nucleic acids based DNA circuits with ultra-low leakage
DNA circuits based on toehold-mediated DNA strand displacement reaction are powerful tools owing to their programmability and predictability....
-
Simultaneous identification of viruses and viral variants with programmable DNA nanobait
Respiratory infections are the major cause of death from infectious disease worldwide. Multiplexed diagnostic approaches are essential as many...
-
Endogenous dual miRNA-triggered dynamic assembly of DNA nanostructures for in-situ dual siRNA delivery
A theranostic strategy of multiple microRNA (miRNA)-triggered in-situ delivery of small interfering RNA (siRNA) can effectively improve the precise...
-
DNA strand displacement reaction: a powerful tool for discriminating single nucleotide variants
Single-nucleotide variants (SNVs) that are strongly associated with many genetic diseases and tumors are important both biologically and clinically....
-
Towards the development of an electrochemical random access DNA memory (e-RADM)
As a result of the exponentially growing amount of information being produced, new data storage solutions are required. DNA has attracted significant...
-
Isothermal self-assembly of multicomponent and evolutive DNA nanostructures
Thermal annealing is usually needed to direct the assembly of multiple complementary DNA strands into desired entities. We show that, with a...
-
A magnetically powered nanomachine with a DNA clutch
Machines found in nature and human-made machines share common components, such as an engine, and an output element, such as a rotor, linked by a...
-
Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture
Three-dimensional cell and organoid cultures rely on the mechanical support of viscoelastic matrices. However, commonly used matrix materials lack...
-
Hierarchical assembly of DNA origami nanostructures
The use of DNA nanotechnology is rapidly growing due to the unprecedented programmability of geometric, mechanical, and dynamic properties. This...
-
Engineering DNA quadruplexes in DNA nanostructures for biosensor construction
DNA quadruplexes are nucleic acid conformations comprised of four strands. They are prevalent in human genomes and increasing efforts are being...
-
A DNA turbine powered by a transmembrane potential across a nanopore
Rotary motors play key roles in energy transduction, from macroscale windmills to nanoscale turbines such as ATP synthase in cells. Despite our...
-
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower
Molecular engineering seeks to create functional entities for modular use in the bottom-up design of nanoassemblies that can perform complex tasks....
-
DNA storage in thermoresponsive microcapsules for repeated random multiplexed data access
DNA has emerged as an attractive medium for archival data storage due to its durability and high information density. Scalable parallel random access...
-
Fabricating higher-order functional DNA origami structures to reveal biological processes at multiple scales
DNA origami technology enables the precise assembly of well-defined two-dimensional and three-dimensional nanostructures with DNA, an inherently...
-
Preparation, applications, and challenges of functional DNA nanomaterials
As a carrier of genetic information, DNA is a versatile module for fabricating nanostructures and nanodevices. Functional molecules could be...
-
Chemical-to-mechanical molecular computation using DNA-based motors with onboard logic
DNA has become the biomolecule of choice for molecular computation that may one day complement conventional silicon-based processors. In general, DNA...
-
Design Theory of Molecular Robots
To realize a “smart” molecular robot that works with sensors and actuators together, it is essential to design DNA circuits that transmit, integrate,...
-
A review on silver-mediated DNA base pairs: methodology and application
The investigation of the interaction between metal ions and DNA has always attracted much attention in the fields of bioinorganic chemistry,...
