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A bone adhesive enhances osteoporotic fracture repair by regulating bone homeostasis
Patients suffering from osteoporotic fractures often require effective fixation and subsequent bone repair. However, the currently available...
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Advanced construction strategies to obtain nanocomposite hydrogels for bone repair and regeneration
Bone tissue engineering is pivotal in facilitating bone reconstruction by promoting persistent angiogenesis and osteogenesis. Initially, the hot gel...
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Remodeling Electrophysiological Microenvironment for Promoting Bone Defect Repair via Electret Hybrid Electrospun Fibrous Mat
Improving the osteogenic properties of bone grafts plays a critical role in the repair and functional restoration of critical-sized bone defects. The...
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A novel fluffy PLGA/HA composite scaffold for bone defect repair
Treatment of bone defects remains crucial challenge for successful bone healing, which arouses great interests in designing and fabricating ideal...
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Bioactive Glasses for Bone Repair Application: A Review of Osteointegration and Controlled Ion Release Capabilities
This mini-review provides a comprehensive overview of bioactive glassesBioactive glasses and their pivotal role in bone repair applications. Bone...
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Graphene and its derivatives as support system ingredient for bone fracture repair
Among different strategies for the treatment of bone-related abnormalities, bone regeneration or replacement has been accepted as most successful....
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Psoralen synergies with zinc implants to promote bone repair by regulating ZIP4 in rats with bone defect
BackgroundThe regulation of dose-dependent biological effects induced by biodegradation is a challenge for the production of biodegradable...
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Delivery of bone morphogenetic protein-2 by crosslinking heparin to nile tilapia skin collagen for promotion of rat calvaria bone defect repair
Collagen has been widely used as a biomaterial for tissue regeneration. At the present, aqua-collagen derived from fish is poorly explored for...
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Ultrasound-Derived Mechanical Stimulation of Alginate Hydrogels for Bone Repair: an In Vitro Study
PurposeCell therapy is a new and evolving treatment for large-scale bone defects. Here, we describe a novel approach that combines hydrogel-based...
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Iron-doped calcium silicate bone cement loaded with carboxymethyl chitosan for bone tissue engineering repair materials
The tricalcium silicate (C 3 S) bone cement has excellent osteogenic properties and is expected to be a material for repairing bone defects. However,...
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Tough and biodegradable polyurethane-silica hybrids with a rapid sol-gel transition for bone repair
Inorganic–organic hybrid materials have promising properties for bone repair because of the covalent bonding between their inorganic and organic...
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Porous Mg–Zn–Ca scaffolds for bone repair: a study on microstructure, mechanical properties and in vitro degradation behavior
Biodegradable porous Mg scaffolds are a promising approach to bone repair. In this work, 3D-spherical porous Mg–1.5Zn–0.2Ca (wt.%) scaffolds were...
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GelMA-based bioactive hydrogel scaffolds with multiple bone defect repair functions: therapeutic strategies and recent advances
Currently, the clinical treatment of critical bone defects attributed to various causes remains a great challenge, and repairing these defects with...
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Guided bone regeneration in long-bone defect with a bilayer mineralized collagen membrane
Bone regeneration for large, critical-sized bone defects remains a clinical challenge nowadays. Guided bone regeneration (GBR) is a promising...
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Bone induction and defect repair by true bone ceramics incorporated with rhBMP-2 and Sr
Objective: To study the bone induction and defect repair of true bone ceramics (TBC) combined with rhBMP-2 and Sr. Methods: MC3T3-E1 cells were used...
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Study of barium-based bioactive glass-ceramic/starch nanobiocomposite as a candidate graft material for bone repair
Bioactive glass-ceramic/polymer composites as implants induce bone bonding and congruent degradability without eliciting adverse immunological...
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Repair of critical diaphyseal defects of lower limbs by 3D printed porous Ti6Al4V scaffolds without additional bone grafting: a prospective clinical study
The repair of critical diaphyseal defects of lower weight-bearing limbs is an intractable problem in clinical practice. From December 2017, we...
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Antimicrobial Metal and Metal Oxide Nanoparticles in Bone Tissue Repair
After the implantation of dental implants or orthopedic device, there is a “race for the surface,” a competitive battle between bacteria and host...
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Comparison of osteogenesis of bovine bone xenografts between true bone ceramics and decalcified bone matrix
Xenograft bone scaffolds have certain advantages such as mechanical strength, osteoinductive properties, sufficient source and safety. This study...
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Hydrogel contained valproic acid accelerates bone-defect repair via activating Notch signaling pathway in ovariectomized rats
The purpose was to observe whether valproic acid (VPA) has a positive effect on bone-defect repair via activating the Notch signaling pathway in an...
