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Antibacterial Electrospun Nanofibrous Materials for Wound Healing
One of the leading causes of wound healing delays is bacterial infection, which limits the process of restoring the histological and functional...
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Biomaterial-based regenerative therapeutic strategies for spinal cord injury
As one of the most intractable neurological diseases, spinal cord injury (SCI) often leads to permanent neurological impairment in patients....
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Lipid polymeric nanoparticles modified with tight junction-modulating peptides promote afatinib delivery across a blood–brain barrier model
BackgroundBrain metastases from non-small cell lung cancer (NSCLC) remain one of the most challenging malignancies. Afatinib (Afa) is an orally...
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Antiviral surfaces and coatings and their mechanisms of action
Viral infections are a serious health challenge, and the COVID-19 pandemic has increased the demand for antiviral measures and treatments for clean...
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Targeting of Drug Nanocarriers
Nanostructured drug delivery systems can be functionalized, through non-covalent interaction or mainly by covalent bonding, with ligands for... -
Noteworthy enhancement of wound-healing activity of triphala biomass metabolite-loaded hydroxyapatite nanocomposite
Hydroxyapatite nanoparticles have been demonstrated as eminent nanomaterials because of their upgraded bioactivity, non-toxicity and biocompatibility...
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Peptide NGR Modified TiO2 Nanofiber Substrate for Circulating Tumor Cells Capture
AbstractThe analysis of circulating tumor cells (CTCs) allows a noninvasive method of “real-time liquid biopsy” from the blood samples of cancer...
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Bio-inspired Synthesis of Nanomaterials
Over the years, human has emphatically developed the skill of synthesizing materials with fascinating properties that resulted in an unprecedented... -
RE-1 Effectively Shields the Cell Self-Effect of Rare Earth Nanomaterials, Reduces Their Toxicity and Improves Their Biological Safety
With the continuous development of the application of nanomaterials in the field of biomedicine, the study of the biological effects of nanomaterials... -
Application of Nanoparticles in Medicine
Nanotechnology is the focus of much research in the last 30 years. The unique optical, electrical, magnetic, chemical, and biological properties of... -
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Nanomaterials in diagnostics, imaging and delivery: Applications from COVID-19 to cancer
AbstractIn the past two decades, the emergence of nanomaterials for biomedical applications has shown tremendous promise for changing the paradigm of...
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Nanomaterials for neurodegenerative diseases: Molecular mechanisms guided design and applications
Successful treatment of neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease...
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A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis
Beta-arrestins (βarrs) critically mediate desensitization, endocytosis and signalling of G protein-coupled receptors (GPCRs), and they scaffold a...
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Targeted delivery of celastrol to glomerular endothelium and podocytes for chronic kidney disease treatment
The etiology of chronic kidney disease (CKD) is complex and diverse, which could be briefly categorized to glomerular- or tubular-originated....
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Progress in transdermal drug delivery systems for cancer therapy
Transdermal drug delivery is an appealing option except for oral and hypodermic administration. With the advancement of skin penetration strategies,...
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End-to-end design of wearable sensors
Wearable devices provide an alternative pathway to clinical diagnostics by exploiting various physical, chemical and biological sensors to mine...
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Molecular recognition and specificity of biomolecules to titanium dioxide from molecular dynamics simulations
Titania (TiO 2 ) is used extensively in biomedical applications; efforts to boost the biocompatibility of TiO 2 include coating it with the titania...
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Conductive Polymers and Their Composites for Biological Application
CPs, as well as their derivatives and composites, are appealing biomaterials due to their biocompatibility, ease of synthesis, simplicity of... -
Peptide therapeutics and assemblies for cancer immunotherapy
Immunotherapy has been considered as one of the most promising strategies for protection against cancer cells due to the tremendous advantages...