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Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans
BackgroundFor some ICU patients, an artificial airway must be established with an endotracheal tube, but Candida albicans can easily adhere to the...
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Microfluidic one-step, aqueous synthesis of size-tunable zeolitic imidazolate framework-8 for protein delivery
Zeolitic imidazolate framework-8 (ZIF-8) with porous structure, biocompatibility, and pH-sensitive release behavior is a promising nanoplatform for...
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In Vivo Mechanistic Study of Superparamagnetic Materials
The recent, fast track advancements in the field of nanotechnology have encouraged the use of nanoparticles as nanomedicine in the biomedical field....
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Nanochitosan-Based Fish Disease Prevention and Control
Globally, diverse infections and diseases abound that have engendered morbidity and mortality in humans and not excluding other biota members....
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Nanomaterials as Drug Delivery Vehicles for Therapy of Parkinson's Disease
Parkinson's disease is a prevalent neurodegenerative disorder characterized by motor impairments and coordination difficulties. With a significant...
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Utilizing dual-pathway energy transfer in upconversion nanoconjugates for reinforced photodynamic therapy
Enhancing the therapeutic effect of existing treatments or develo** new non-invasive treatments are important measures to achieve high-efficiency...
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Nanoparticle targeting cGAS-STING signaling in disease therapy
The cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon (IFN) genes (cGAS-STING) signaling pathway is crucial...
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An oxygen reservoir-irrigated photoimmunotherapy of malignant melanoma
Tumor hypoxia is the pivotal factor limiting the therapeutic efficacy of photodynamic therapy (PDT), and can be partly improved by either the oxygen...
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A composite peptide-supramolecular microneedle system for melanoma immunotherapy
Despite recent advances in melanoma treatment through the use of antibody immunotherapy, the clinical benefit remains restricted by its inefficient...
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Emerging applications of extracellular vesicles in tumor therapy
Extracellular vesicles (EVs) have tremendous potential as nano/micron-sized drug delivery carriers. Their physical, chemical and biological...
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Induction of ferroptosis by artesunate nanoparticles is an effective therapeutic strategy for hepatocellular carcinoma
Artesunate (ART) has great value in the field of tumor therapy. Interestingly, in this study, we found that ART could obviously induce ferroptosis in...
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Bioenzyme-based nanomedicines for enhanced cancer therapy
Bioenzymes that catalyze reactions within living systems show a great promise for cancer therapy, particularly when they are integrated with...
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Resveratrol-loaded gold nanoparticles enhance caspase-mediated apoptosis in PANC-1 pancreatic cells via mitochondrial intrinsic apoptotic pathway
BackgroundPancreatic ductal adenocarcinoma (PDAC) remains one of the most fatal malignancies. Several chemotherapies employing fluorouracil (5-FU)...
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Recent advances in molecular and nanoparticle probes for fluorescent bioanalysis
With the increasing emphasis on ecological safety and physical health, the detection and treatment of harmful substances and diseases are becoming...
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Nanocarriers and Nano Drug Delivery Therapy in Neuro Diseases
Neurological diseases pose significant challenges in drug delivery due to the complex and delicate nature of the central nervous system (CNS)....
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Mitochondria-targeting self-assembled nanoparticles derived from triphenylphosphonium-conjugated cyanostilbene enable site-specific imaging and anticancer drug delivery
Subcellular organelle-specific nanoparticles for simultaneous tumor targeting, imaging, and drug delivery are of enormous interest in cancer therapy....
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Nanomedicine: Insight Analysis of Emerging Biomedical Research and Developments
The field of nanomedicine has undergone a revolution owing to the specific optical, electrical, and mechanical behaviors of nanomaterials that are...
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Nanocarriers for Tracking and Treating Epilepsy, and Seizures Management
Epilepsy, the neurological disorder causes abnormal electrical discharge of the brain that leads to seizures, is a severe healthcare problem. The...
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Plasmonic nanostructures acting as a light-driven O2-sensitive nitroreductase mimic for enhanced photochemical oxidation of para-aminothiophenol
Nanozymes, as a novel form of enzyme mimics, have garnered considerable interest. Despite overcoming the main disadvantages of their natural analogs,...
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Autologous material-inspired drug delivery systems
Pursuing personalized medicine has spurred the development of drug delivery systems inspired by autologous materials, underscoring the transition...