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Photo-crosslinked gelatin methacrylate hydrogels with mesenchymal stem cell and endothelial cell spheroids as soft tissue substitutes
Tumors, trauma, and congenital defects require volume restoration of soft tissues. Tissue engineering provides an alternative source for substituting...
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Graphene foam/hydrogel scaffolds for regeneration of peripheral nerve using ADSCs in a diabetic mouse model
The functional recovery of peripheral nerve injury (PNI) is unsatisfactory, whereas diabetes mellitus (DM) and its related complications further...
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Effect of Type 2 Diabetes Mellitus Patient’s Serum as Preconditioning on Umbilical Cord Mesenchymal–Derived Secretome Production
PurposeThe trend of regenerative medicine is shifting toward the potency of Umbilical Cord Mesenchymal–derived Secretome (UC-MSCs-derived secretome)...
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Tissue Engineering and Regenerative Medicine
Biomaterials and biomedical devices can be constructed of a variety of materials, and depending on the end use, incorporation of bioactive species...
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Sensing of Physical Factors by Cells: Electric Field, Mechanical Forces, Physical Plasma and Light—Importance for Tissue Regeneration
The development of new biomaterials and medical devices has become a growing field of interdisciplinary research. The medical devices for tissue and...
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Interplay of reactive oxygen species (ROS) and tissue engineering: a review on clinical aspects of ROS-responsive biomaterials
Reactive oxygen species (ROS) refers to the reactive molecules and free radicals of oxygen generated as the by-products of aerobic respiration....
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Regenerative capacity of trophoblast stem cell-derived extracellular vesicles on mesenchymal stem cells
BackgroundHuman mesenchymal stem cells (MSCs) are therapeutic for clinical applications because of their excellent immunomodulatory and multiple...
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Effect of storage conditions on the quality of equine and canine mesenchymal stem cell derived nanoparticles including extracellular vesicles for research and therapy
Nanoparticles including extracellular vesicles derived from mesenchymal stem cells are of increasing interest for research and clinical use in...
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Nanocomposites Based on Biodegradable Polymers for Biomedical Applications
Regenerative medicine has sought new alternatives of materials capable of being used in humans for different purposes, with low or no cytotoxicity,...
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Human Umbilical Cord–derived Mesenchymal Stem Cells into Oligodendrocyte-like Cells using Triiodothyronine as an Inducer: a Rapid and Efficient Protocol
AbstractMultiple sclerosis (MS) is a central nervous system (CNS)–specific autoimmune disease which is associated with severe destruction of myelin....
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Chitooligosaccharides: Preparation and Applications in Food and Nutraceuticals
Chitooligosaccharide (COS) is the hydrolyzed product of chitosan (CS). Various chemical, physical, and enzymatic methods have been employed to...
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Indirect versus direct 3D printing of hydrogel scaffolds for adipose tissue regeneration Lana Van Damme, Emilie Briant, Phillip Blondeel, Sandra Van Vlierberghe
There exists a need for an innovative reconstructive approach for breast reconstruction, tackling current drawbacks and limitations present in the...
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Photothermal-Triggered Structural Change of Nanofiber Scaffold Integrating with Graded Mineralization to Promote Tendon–Bone Healing
Scaffolds functionalized with graded changes in both fiber alignment and mineral content are more appealing for tendon-bone healing. This study...
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Extracellular matrix sheet modified with VEGF-loaded nanoparticles for bladder regeneration
Extracellular matrix (ECM) bioscaffolds have been widely studied to repair bladder tissue defects; however, insufficient angiogenesis and weak...
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Mesenchymal Stem Cell-Enriched Hydrogels for the Treatment of Knee Joint Disorders: A Systematic Review
PurposeThe knee is a complex joint that can be harmed by injuries including osteochondral defects and degenerative diseases such as osteoarthritis...
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14-3-3ε protein-loaded 3D hydrogels favor osteogenesis
3D printing has emerged as vanguard technique of biofabrication to assemble cells, biomaterials and biomolecules in a spatially controlled manner to...
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The Effect of Co-treating Human Mesenchymal Stem Cells with Epigallocatechin Gallate and Hypoxia-Inducible Factor-1 on the Expression of RANKL/RANK/OPG Signaling Pathway, Osteogenesis, and Angiogenesis Genes
AbstractMesenchymal stem cells (MSCs) were considered the promising source in the regeneration of bone tissue. These cells have been known to have...
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Nanotechnology in Dental Implantology
Nanotechnology can be employed in changing the implant surface chemistry and topography which can in turn affect osteointegration, the most crucial...
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20(S)-hydroxycholesterol and simvastatin synergistically enhance osteogenic differentiation of marrow stromal cells and bone regeneration by initiation of Raf/MEK/ERK signaling
Previous studies have demonstrated the significant roles of simvastatin (SVA) and oxysterols in the osteogenesis process. In this study, we evaluate...
