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A mechanistic approach to weighting edge-effects in landscape connectivity assessments
ContextUnderstanding landscape functional connectivity is critical for nature conservation in fragmented landscapes. Spatially explicit...
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A phylogenetic approach for weighting genetic sequences
BackgroundMany important applications in bioinformatics, including sequence alignment and protein family profiling, employ sequence weighting schemes...
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Genoty** marker density and prediction models effects in long-term breeding schemes of cross-pollinated crops
Key MessageIn genomic recurrent selection, the more markers, the better because they buffer the linkage disequilibrium losses caused by recombination...
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The effect of an objective weighting of the global food security index’s natural resources and resilience component on country scores and ranking
Composite indicators have gained popularity in various research areas. However, the determination of an appropriate weighting method is challenging....
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Pre-selection against a lethal recessive allele in breeding schemes with optimum-contribution selection or truncation selection
BackgroundWe tested the hypothesis that breeding schemes with a pre-selection step, in which carriers of a lethal recessive allele (LRA) were culled,...
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Does multi-way, long-range chromatin contact data advance 3D genome reconstruction?
BackgroundMethods for inferring the three-dimensional (3D) configuration of chromatin from conformation capture assays that provide strictly pairwise...
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Substitution matrix based color schemes for sequence alignment visualization
BackgroundVisualization of multiple sequence alignments often includes colored symbols, usually characters encoding amino acids, according to some...
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Assessment of Agricultural Sustainability in the Indo-Gangetic Plains of India: An Application of the Indicator Framework
Although there is a consensus on the definition of agricultural sustainability, there is a dearth of empirical evidence because of methodological...
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A gene based combination test using GWAS summary data
BackgroundGene-based association tests provide a useful alternative and complement to the usual single marker association tests, especially in...
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Optimum mating designs for exploiting dominance in genomic selection schemes for aquaculture species
BackgroundIn commercial fish, dominance effects could be exploited by predicting production abilities of the offspring that would be generated by...
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Design-based spatial interpolation with data driven selection of the smoothing parameter
In the inverse distance weighting interpolation the interpolated, value is a weighted mean of the sampled values, with weights decreasing with the...
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Participation bias in the UK Biobank distorts genetic associations and downstream analyses
While volunteer-based studies such as the UK Biobank have become the cornerstone of genetic epidemiology, the participating individuals are rarely...
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Xtrapol8 enables automatic elucidation of low-occupancy intermediate-states in crystallographic studies
Unstable states studied in kinetic, time-resolved and ligand-based crystallography are often characterized by a low occupancy, which hinders...
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Favoring the hierarchical constraint in penalized survival models for randomized trials in precision medicine
BackgroundThe research of biomarker-treatment interactions is commonly investigated in randomized clinical trials (RCT) for improving medicine...
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Modeling fish habitat: model tuning, fit metrics, and applications
Knowledge of the habitat associations and spatial–temporal distributions of wild animals is essential for successful ecosystem management, and...
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Integration of landmark and saccade target signals in macaque frontal cortex visual responses
Visual landmarks influence spatial cognition and behavior, but their influence on visual codes for action is poorly understood. Here, we test...
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Assessment of Indicators for Climate Smart Management in Mountain Forests
This chapter addresses the concepts and methods to assess quantitative indicators of Climate-Smart Forestry (CSF) at stand and management unit...
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Small Animal PET Imaging: Towards an Imaging Analysis Approach for System Average Performance Conclusion
The purpose of this study is to present a novel small animal PET imaging system, which can be integrated with a small animal CT or MRI imaging in a...
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Diversity Patterns in Macroecological Assemblages
In this chapter, we discuss other patterns that can be obtained from assemblages from a macroecological perspective, expanding the reasoning of the...
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Phylogenetic relationships in Stephanopinae: systematics of Stephanopis and Sidymella based on morphological characters (Araneae: Thomisidae)
A matrix of 117 morphological characters scored for 77 terminal taxa was subjected to parsimony analysis under equal and implied weighting schemes...
