Search
Search Results
-
Evolution of Vitamin D Status and Vitamin D Receptor Gene Expression Among Professional Handball Athletes During a Competitive Period. Relationship with Body Composition, Calcium, Magnesium and Phosphorous
Introduction : A generalized risk of vitamin D deficiency exists worldwide affecting also professional and elite athletes. This study assesses the...
-
Vitamin D receptor gene variants and serum vitamin D in childhood autism spectrum disorder
ObjectiveThis study aimed to examine the correlation between polymorphisms in vitamin D receptor (VDR) gene and serum vitamin D, and to determine...
-
Vitamin D receptor gene BsmI (rs1544410) polymorphism: role in multiple sclerosis and genotype-phenotype correlations
BackgroundMultiple sclerosis (MS) has a complex pathophysiology which depends on many endogenous and exogenous factors. Vitamin D involvement has...
-
Gene expression profiling of vitamin D metabolism enzymes in leukemia and lymphoma patients: molecular aspect interplay of VDR, CYP2R1, and CYP24A1
BackgroundVitamin D deficiency is prevalent among the Indonesian population, particularly in individuals diagnosed with leukemia-lymphoma. The...
-
Association between vitamin D receptor gene FokI polymorphism and mortality in patients with sepsis
BackgroundSepsis is life-threatening organ dysfunction as a result of the host’s dysregulated immune response to infection. The vitamin D receptor ( VDR...
-
Delving the vitamin D receptor variation and expression profiles in the context of type 2 diabetes among families
BackgroundVitamin D is essential for insulin secretion and sensitivity. Consequently, its inadequacy is linked to higher insulin resistance and Type...
-
Status of Vitamin D Receptor Gene Polymorphism and 25-Hydroxy Vitamin D Deficiency with Essential Hypertension
Essential hypertension (EH) is a multifactorial and complex disease with high rate of incidence and associated co-morbidities. Previous studies do...
-
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4
Activating transcription factor 4 (ATF4) is one of the key effectors of endoplasmic reticulum stress (ERS), ATF4/CHOP pathway-mediated ERS plays an...
-
Genetic variants of vitamin D, estrogen α, parathyroid and collagen type I alpha receptor gene and its influence on circulating serum osteocalcin in postmenopausal osteoporosis: A cohort study
AbstractOsteocalcin is an abundant, highly conserved bone specific protein and the serum levels of OC have been used as a biochemical marker of bone...
-
An Updated Trial Sequential Meta-analysis of Vitamin D Receptor Gene Polymorphism (Fok1, Bsm1, Taq1 and Apa1) and Risk to Tuberculosis
Vitamin D receptor (VDR) is one of the most widely studied genes for the Tuberculosis (TB) susceptibility. Several studies have been conducted to...
-
The vitamin D receptor gene variants, ApaI, TaqI, BsmI, and FokI in diabetic foot ulcer and their association with oxidative stress
IntroductionTo date, numerous disorders have been linked to vitamin D deficiency. Several lines of evidence indicate a relationship between vitamin D...
-
Genetic susceptibility of vitamin D receptor gene polymorphisms on autosomal recessive primary microcephaly patients in Pakistani population: a case-control and in-silico study
BackgroundAutosomal recessive primary microcephaly (MCPH) is a rare genetic disorder that leads to reduced cerebral cortex caused by a mutation in...
-
Role of VDR gene polymorphisms and vitamin D levels in normal and overweight patients with PCOS
Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in women. In recent years, the effects of vitamin D receptor (VDR) gene...
-
Structural diversification of vitamin D using microbial biotransformations
AbstractVitamin D deficiencies are linked to multiple human diseases. Optimizing its synthesis, physicochemical properties, and delivery systems...
-
Polymorphisms in vitamin D receptor genes and its relation with susceptibility to brucellosis: a case-control study
ObjectiveOne of the systemic infections is Brucellosis which is caused by facultative intracellular bacteria of the genus Brucell a. Vitamin D is a...
-
Calcitriol Inhibits NaAsO2 Triggered Hepatic Stellate Cells Activation and Extracellular Matrix Oversecretion by Activating Nrf2 Signaling Pathway Through Vitamin D Receptor
Previous studies, including our own, have demonstrated that arsenic exposure can induce liver fibrosis, while the underlying mechanism remains...
-
Vitamin D and potential effects on cancers: a review
Cancer is characterized by the abnormal and uncontrollable division and growth of cells that can infiltrate tissues and alter normal physiological...
-
Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state
As a highly heterogeneous tumor, pancreatic ductal adenocarcinoma (PDAC) exhibits non-uniform responses to therapies across subtypes. Overcoming...
-
Vitamin D status modulates mitochondrial oxidative capacities in skeletal muscle: role in sarcopenia
Skeletal muscle mitochondrial function is the biggest component of whole-body energy output. Mitochondrial energy production during exercise is...
-
Modeling cellular responses to serum and vitamin D in microgravity using a human kidney microphysiological system
The microgravity environment aboard the International Space Station (ISS) provides a unique stressor that can help understand underlying cellular and...
