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The mitochondrial carrier homolog 2 is involved in down-regulation of influenza A virus replication
BackgroundThe mitochondrial carrier homolog 2 (MTCH2) is a mitochondrial outer membrane protein regulating mitochondrial metabolism and functions in...
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In situ-formable, dynamic crosslinked poly(ethylene glycol) carrier for localized adeno-associated virus infection and reduced off-target effects
The adeno-associated virus (AAV) is a potent vector for in vivo gene transduction and local therapeutic applications of AAVs, such as for skin...
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Acyl carrier protein tag can enhance tobacco etch virus protease stability and promote its covalent immobilisation
AbstractFusion expression is widely employed to enhance the solubility of recombinant proteins. However, removal of the fusion tag is often required...
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Virus-induced changes in host plant phenotype cue behavioral changes in Aphis glycines that enhance acquisition and transmission of soybean mosaic virus
Vector-borne viruses can modify the phenotype of their host plants to manipulate the behavior of their vectors and maximize their dissemination. The...
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Hepatitis B virus-induced hepatocellular carcinoma: a persistent global problem
Hepatitis B virus (HBV) infections are highly prevalent globally, representing a serious public health problem. The diverse modes of transmission and...
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Probing Substrate-Loaded Carrier Proteins by Nuclear Magnetic Resonance
Carrier proteins (CPs) are central actors in nonribosomal peptide synthetases (NRPSs) as they interact with all catalytic domains, and because they... -
Endosymbionts modulate virus effects on aphid-plant interactions
Vector-borne pathogens frequently modify traits of their primary hosts and vectors in ways that influence disease transmission. Such effects can...
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An oncolytic virus–T cell chimera for cancer immunotherapy
The efficacy of oncolytic adenoviruses (OAs) for cancer therapy has been limited by insufficient delivery to tumors after systemic injection and the...
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Structural basis of hepatitis B virus receptor binding
Hepatitis B virus (HBV), a leading cause of develo** hepatocellular carcinoma affecting more than 290 million people worldwide, is an enveloped DNA...
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Turnip Mosaic Virus Nanoparticles: A Versatile Tool in Biotechnology
Within plant molecular farming (PMF), the use of viruses and virus-like particles (VLPs) is increasingly gaining momentum due to the vast array of... -
Prevalence of bovine herpes virus-1 among reproductive disorders in cattle and buffaloes in Punjab region of India
Bovine Herpes Virus (BHV-1) is a virus prevalent among cattle and buffaloes which accounts for considerable reproductive failures. This study was...
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The application of a 4D-printed chitosan-based stem cell carrier for the repair of corneal alkali burns
BackgroundCorneal alkali burns can lead to ulceration, perforation, and even corneal blindness due to epithelial defects and extensive cell necrosis,...
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Regulation of zinc-dependent enzymes by metal carrier proteins
Zn 2+ ions are essential in many physiological processes, including enzyme catalysis, protein structural stabilization, and the regulation of many...
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Subclinical circulation of Chicken infectious anaemia virus- A Sero-molecular study
Chicken infectious anaemia—an important immunosuppressive viral disease of chicken—gained much attention in the recent past. Based on huge mortality...
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Epstein–Barr virus tegument protein BGLF2 in exosomes released from virus-producing cells facilitates de novo infection
BackgroundViruses must adapt to the environment of their host cells to establish infection and persist. Diverse mammalian cells, including...
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Perspectives on plant virus diseases in a climate change scenario of elevated temperatures
Global food production is at risk from many abiotic and biotic stresses and can be affected by multiple stresses simultaneously. Virus diseases...
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Engineering of Chlamydomonas reinhardtii chloroplast for mucosal immunotherapeutic against Newcastle disease virus
Newcastle disease virus (NDV) is a devastating virus for the poultry industry, resulting in huge economic losses due to high morbidity and mortality....
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Establishment of a neutralization assay for Nipah virus using a high-titer pseudovirus system
ObjectiveTo construct a high-titer Nipah pseudovirus packaging system using the HIV lentivirus backbone vector and establish a safe neutralization...
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Reprogramming of glucose metabolism in virus infected cells
Viral infection is a kind of cellular stress that leads to the changes in cellular metabolism. Many metabolic pathways in a host cell such as...
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Insights into the early transcriptomic response against watermelon mosaic virus in melon
BackgroundWatermelon mosaic virus (WMV) is one of the most prevalent viruses affecting melon worldwide. Recessive resistance to WMV in melon has...