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Schultriene and nigtetraene: two sesterterpenes characterized from pathogenetic fungi via genome mining approach
AbstractFungal bifunctional terpene synthases (BFTSs) have been reported to contribute to the biosynthesis of a variety of di/sesterterpenes via...
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The antifungal properties of terpenoids from the endophytic fungus Bipolaris eleusines
A series of terpenoids ( 1–17 ), comprising six new compounds designated bipolariterpenes A-F ( 1–6 ) and eleven recognized compounds ( 7–17 ), were...
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An update on chemistry and bioactivities of secondary metabolites from the marine algal-derived endophytic fungi
Marine algal-derived endophytic fungi (MAEF) have proven to be unabated sources of novel secondary metabolites with remarkable scaffold diversity,...
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Microbial Production of Terpenes
Sustainability is one of the main challenges facing humankind in the twenty-first century due to the continuous increase in the demand for energy and...
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Chemical and biological diversity of new natural products from marine sponges: a review (2009–2018)
Marine sponges are productive sources of bioactive secondary metabolites with over 200 new compounds isolated each year, contributing 23% of approved...
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Unearthing the fungal endophyte Aspergillus terreus for chemodiversity and medicinal prospects: a comprehensive review
Aspergillus terreus microorganism represents a promising prospective source for drug discovery since it is rich in diverse kinds of bioactive...
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Indonesian marine and its medicinal contribution
The archipelagic country of Indonesia is populated by the densest marine biodiversity in the world which has created strong global interest and is...
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Genome-guided investigation of anti-inflammatory sesterterpenoids with 5-15 trans-fused ring system from phytopathogenic fungi
AbstractFungal terpenoids catalyzed by bifunctional terpene synthases (BFTSs) possess interesting bioactive and chemical properties. In this study,...
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Curative Potential of High-Value Phytochemicals on COVID-19 Infection
AbstractMedicinal plants and their therapeutically promising chemical compounds belonging to the valued category of ‘traditional medicine’ are...
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A new α-pyrone from Arthrinium pseudosinense culture medium and its estrogenic activity in MCF-7 cells
A new α -pyrone analog, arthrifuranone A ( 1 ) was isolated from an EtOAc-extract of Arthrinium pseudosinense culture medium. The isolation workflow was...
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Recently duplicated sesterterpene (C25) gene clusters in Arabidopsis thaliana modulate root microbiota
Land plants co-speciate with a diversity of continually expanding plant specialized metabolites (PSMs) and root microbial communities (microbiota)....
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Cydonia oblonga Mill.: Wound Healing Properties
Traditional and indigenous medicines make significant use of natural raw materials and derivatives of natural products. Cydonia oblonga Mill,...
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Discovery of Bioactive Metabolites from the Genus Arthrinium
The ascomycete genus Arthrinium (class, Sordariomycetes; family, Apiosporaceae) comprises approximately 88 species distributed worldwide. It has been...
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Plant geranylgeranyl diphosphate synthases: every (gene) family has a story
Plant isoprenoids (also known as terpenes or terpenoids) are a wide family of primary and secondary metabolites with multiple functions. In...
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Recent advances in lycopene and germacrene a biosynthesis and their role as antineoplastic drugs
Sesquiterpenes and tetraterpenes are classes of plant-derived natural products with antineoplastic effects. While plant extraction of the...
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Terpenoid diversity in sunflower (Helianthus annuus L.) and their potential in crop protection
Every year, more than 50 million tons of Helianthus annuus L. are produced mainly for the sunflower oil industry. It is a plant consumed worldwide,...
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The Production of High-Value Secondary Metabolites Through Hairy Root Transformation in the Presence of Brassinosteroids
Plants are the key source of value-added bioactive compounds of medicinal repute. Extended usage of these secondary metabolites (SM) in several...
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Coordination among flower pigments, scents and pollinators in ornamental plants
Flower color and scent, crucial qualitative characteristics of ornamental plants, display extensive variation. These distinct pigments and scents...
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Neem secretory cells: developmental cytology and indications of cell autotoxicity
The neem tree ( Azadirachta indica A.Juss.) contains a range of biologically active compounds—mainly triterpenoids produced in single secretory cells,...
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Anti-lung cancer properties of cyanobacterial bioactive compounds
Lung cancer, the most prevalent gender-independent tumor entity in both men and women, is among the leading cause of cancer-related deaths worldwide....
