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Zygocin – a monomeric protein toxin secreted by virus-infected Zygosaccharomyces bailii
Zygocin, a protein toxin secreted by virus-infected strains of the osmotolerant spoilage yeast Zygosaccharomyces bailii kills a broad spectrum of...
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Complex and pleiotropic signaling pathways regulated by the secreted protein augurin
The secreted protein augurin, the product of the tumor suppressor gene Ecrg4 , has been identified as a peptide hormone in the human proteome in 2007....
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Assays for Studying Pseudomonas aeruginosa Secreted Proteases
Proteolytic activity plays an essential role in Pseudomonas aeruginosa adaptation and survival in challenging environments, including the infection...
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Use of Bastion for the Identification of Secreted Substrates
Bacteria use secretion systems to translocate numerous proteins into and across cell membranes, but have evolved more specialized secretion systems...
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S. cerevisiae K28 toxin – a secreted virus toxin of the A/B family of protein toxins
Since the initial discovery of toxin-secreting killer strains in the yeast Saccharomyces cerevisiae more than 40 years ago, continuous research on...
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In silico identification of a promising inhibitor of Fusarium oxysporum f. sp. Lycopersici, Secreted in Xylem 1 protein
Fusarium oxysporum f. sp. Lycopersici (FOL) is a soilborne pathogen that infects tomato plants and inflicts severe damage, resulting in heavy yield...
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The secreted peptide BATSP1 promotes thermogenesis in adipocytes
Although brown adipose tissue (BAT) has historically been viewed as a major site for energy dissipation through thermogenesis, its endocrine function...
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TGF-β1 upregulates secreted protein acidic and rich in cysteine expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome
BackgroundOvarian hyperstimulation syndrome (OHSS) is a serious complication during in vitro fertilization (IVF) treatment. The upregulation of...
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Secreted protein markers in oral squamous cell carcinoma (OSCC)
BackgroundOral squamous cell carcinoma (OSCC) is a main cause of oral cancer mortality and morbidity in central south Asia. To improve the clinical...
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Lactic acid bacteria secreted proteins as potential Listeria monocytogenes quorum sensing inhibitors
Listeria monocytogenes is an important human and animal pathogen able to cause an infection named listeriosis and is mainly transmitted through...
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Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells
BackgroundVentral midbrain (VM) dopaminergic progenitor cells derived from human pluripotent stem cells have the potential to replace endogenously...
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Towards unlocking the biocontrol potential of Pichia kudriavzevii for plant fungal diseases: in vitro and in vivo assessments with candidate secreted protein prediction
BackgroundPlant fungal pathogens cause substantial economic losses through crop yield reduction and post-harvest storage losses. The utilization of...
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Protein–Protein Interactions: Oxidative Bacterial Two Hybrid
Protein–protein interaction studies are essential to understand how proteins organize themselves into interaction networks and thus influence...
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M2 macrophage-secreted exosomes promote metastasis and increase vascular permeability in hepatocellular carcinoma
BackgroundMetastasis is a key feature of malignant tumors and significantly contributes to their high mortality, particularly in hepatocellular...
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Controlling the Immune Response to Zebrafish Spinal Cord Injury via Extracellular Vesicles Secreted by Activated Monocyte-like Cells
AbstractThe immune response to spinal cord injury (SCI) is implemented via local and systemic inflammation, followed by repair and...
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Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling
Activity-based protein profiling (ABPP) has emerged as a versatile biochemical method for studying enzyme activity under various physiological...
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Unraveling the Virulence Factors and Secreted Proteins of an Environmental Isolate Enterobacter sp. S-16
Members of the Enterobacte r genus include many pathogenic microbes of humans and plants, secrete proteins that contribute to the interactions of...
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A unique effector secreted by Pseudozyma flocculosa mediates its biocontrol activity
BackgroundPseudozyma flocculosa is a highly efficient biocontrol agent (BCA) of powdery mildews whose mode of action remains elusive. It is known to...
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Paracrine signalling between keratinocytes and SVF cells results in a new secreted cytokine profile during wound closure
Stromal vascular fraction (SVF) cells, and the adipose-derived mesenchymal stem cells they contain, have shown enhanced wound healing in vitro and in...
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Candidatus Phytoplasma ziziphi encodes non-classically secreted proteins that suppress hypersensitive cell death response in Nicotiana benthamiana
Increasing evidence is proving the biological significance of the phytoplasma-secreted proteins. However, besides a few Sec-dependent secretory...
