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Structural Features of the Wall of the Ascending Aorta of Premature Rats
AbstractPremature birth has an obvious effect on all the systems of the body, including the cardiovascular system, which undergoes significant...
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The impact of premature birth on auditory-visual processes in very preterm schoolchildren
Interactions between stimuli from different sensory modalities and their integration are central to daily life, contributing to improved perception....
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Effect of nonsense-mediated mRNA decay factor SMG9 deficiency on premature aging in zebrafish
SMG9 is an essential component of the nonsense-mediated mRNA decay (NMD) machinery, a quality control mechanism that selectively degrades aberrant...
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MicroRNA Cargo in Wharton’s Jelly MSC Small Extracellular Vesicles: Key Functionality to In Vitro Prevention and Treatment of Premature White Matter Injury
Preterm birth is the leading cause of childhood morbidity and mortality and can result in white matter injury (WMI), leading to long-term...
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NMR-based metabolic profiling of children with premature adrenarche
IntroductionPremature adrenarche (PA) for long time was considered a benign condition but later has been connected to various diseases in childhood...
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Draft Genome Sequence of Candida saopaulonensis from a Very Premature Infant with Sepsis
The rare fungus Candida saopaulonensis has never been reported to be associated with human infection. We report the draft genome sequence of the...
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Longitudinal development of the airway metagenome of preterm very low birth weight infants during the first two years of life
Preterm birth is accompanied with many complications and requires severe therapeutic regimens at the neonatal intensive care unit. The influence of...
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Trajectories of brain and behaviour development in the womb, at birth and through infancy
Birth is often seen as the starting point for studying effects of the environment on human development, with much research focused on the capacities...
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Deleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice
Premature ovarian insufficiency (POI) is a heterogeneous female disorder characterized by the loss of ovarian function before the age of 40. It...
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Genetic Testing in Pregnancy to Assess the Risk of Preterm Birth
Preterm birth (PTB) is one of the leading causes of infant and child mortality under 5 years of age. PTB infants have long-term health consequences... -
The Therapeutic Potential of Human Umbilical Cord Derived Mesenchymal Stem Cells for the Treatment of Premature Ovarian Failure
Premature ovarian failure (POF) affects 1% of women under 40, leading to infertility. The clinical symptoms of the POF include hypoestrogenism, lack...
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Meta-analysis reveals the vaginal microbiome is a better predictor of earlier than later preterm birth
BackgroundHigh-throughput sequencing measurements of the vaginal microbiome have yielded intriguing potential relationships between the vaginal...
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Preterm birth is associated with xenobiotics and predicted by the vaginal metabolome
Spontaneous preterm birth (sPTB) is a leading cause of maternal and neonatal morbidity and mortality, yet its prevention and early risk...
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Human Amniotic Epithelial Stem Cells Alleviate Autoimmune Premature Ovarian Insufficiency in Mice by Targeting Granulosa Cells via AKT/ERK Pathways
Autoimmune factors play an important role in premature ovarian insufficiency (POI). Human amniotic epithelial stem cells (hAESCs) have recently shown...
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Menstrual blood-derived endometrial stem cell, a unique and promising alternative in the stem cell-based therapy for chemotherapy-induced premature ovarian insufficiency
Chemotherapy can cause ovarian dysfunction and infertility since the ovary is extremely sensitive to chemotherapeutic drugs. Apart from the...
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Combination of bone marrow mesenchymal stem cells and moxibustion restores cyclophosphamide-induced premature ovarian insufficiency by improving mitochondrial function and regulating mitophagy
BackgroundPremature ovarian insufficiency (POI) is a major cause of infertility. In this study, we aimed to investigate the effects of the...
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Comparison of the different animal modeling and therapy methods of premature ovarian failure in animal model
Incidence of premature ovarian failure (POF) is higher with the increase of the pace of life. The etiology of POF is very complex, which is closely...
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Prophylactic administration of human amniotic fluid stem cells suppresses inflammation-induced preterm birth via macrophage polarization
Ascending inflammation from the vagina is a major cause of preterm birth. Currently, this condition—especially when uncontrolled—has no effective...
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Genetic aetiology of Down syndrome birth: novel variants of maternal DNMT3B and RFC1 genes increase risk of meiosis II nondisjunction in the oocyte
The aim of the present work was to explore the intriguing association of maternal folate regulator gene polymorphisms and mutations with the...