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The spatial transcriptomic landscape of human gingiva in health and periodontitis
The gingiva is a key oral barrier that protects oral tissues from various stimuli. A loss of gingival tissue homeostasis causes periodontitis, one of...
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Akkermansia muciniphila inhibited the periodontitis caused by Fusobacterium nucleatum
Periodontitis is the most important cause of tooth loss in adults and is closely related to various systemic diseases. Its etiologic factor is plaque...
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Combined assessment of lysine and N-acetyl cadaverine levels assist as a potential biomarker of the smoker periodontitis
Periodontitis is an inflammatory condition of supporting structures of teeth leading to attachment and bone loss. Cigarette smoking is the single...
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Does crocin create new hope for the treatment of oral problems? A focus on periodontitis
According to the World Health Organization (WHO) reports, oral health has an indispensable role in the maintenance of human public health. However,...
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Inflammatory Biomarkers in Periodontitis and Their Effect on the Stem/Progenitor Cells: Molecular Basis of Bone Resorption and Bone Regeneration
Periodontitis is considered one of the most chronic inflammatory diseases damaging the soft and hard tissues supporting the teeth. In periodontitis,...
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Infrared laser therapy decreases systemic oxidative stress and inflammation in hypercholesterolemic mice with periodontitis
BackgroundNear-infrared irradiation photobiomodulation (NIR-PBM) has been successfully used in periodontal treatment as an adjuvant tool to locally...
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Exploration of the underlying comorbidity mechanism in psoriasis and periodontitis: a bioinformatics analysis
BackgroundIncreasing evidence indicates that psoriasis (PSO) and periodontitis (PD) are likely to occur together, however, the underlying mechanism...
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Nitrate and a nitrate-reducing Rothia aeria strain as potential prebiotic or synbiotic treatments for periodontitis
A few studies indicate that nitrate can reduce dysbiosis from a periodontitis point of view. However, these experiments were performed on samples...
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Inflammatory Biomarkers in Periodontitis and Their Effect on the Stem/Progenitor Cells: Molecular Basis of Bone Resorption and Bone Regeneration
Periodontitis is considered one of the most chronic inflammatory diseases damaging the soft and hard tissues supporting the teeth. In periodontitis,...
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Periapical bacterial disinfection is critical for dental pulp regenerative cell therapy in apical periodontitis in dogs
BackgroundApplication of pulp regenerative cell therapy for mature teeth with periapical lesions is a critical clinical challenge. The bacterial...
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A brief review of vitamin D as a potential target for the regulation of blood glucose and inflammation in diabetes-associated periodontitis
Diabetes is a metabolic disorder associated with various complications, including periodontitis. The risk of periodontitis is increased in patients...
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Effect of endoplasmic reticulum stress-induced apoptosis in the role of periodontitis on vascular calcification in a rat model
The present study aimed to investigate the mechanism(s) through which endoplasmic reticulum stress (ERS)-induced apoptosis, in the role of...
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Pathogenic Microbial Profile and Antibiotic Resistance Associated with Periodontitis
AbstractPhenoty** based on conventional microbiological, physiological, and molecular analysis by using ARDRA technique was developed with the aim...
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Polymorphisms and haplotypes in the Interleukin 17 Alfa gene: potential effect of smoking habits in the association with periodontitis and type 2 diabetes mellitus
Few studies evaluate interrelationships between periodontitis (P) and Type 2 Diabetes Mellitus (T2DM). The aim of this study is to investigate the...
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The diagnostic role of salivary biomarkers of oxidative stress and inflammatory status and their relationship in periodontitis stage III and grade C
Periodontitis is bacterial infection characterized by persistent inflammation, damages connective tissue and alveolar bone destruction. The present...
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Highly perturbed genes and hub genes associated with type 2 diabetes in different tissues of adult humans: a bioinformatics analytic workflow
Type 2 diabetes (T2D) has a complex etiology which is not yet fully elucidated. The identification of gene perturbations and hub genes of T2D may...
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Zinc oxide nanoparticles functionalized with cinnamic acid for targeting dental pathogens receptor and modulating apoptotic genes in human oral epidermal carcinoma KB cells
BackgroundOral diseases are often attributed to dental pathogens such as S. aureus , S. mutans , E. faecalis , and C. albicans . In this research work,...
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The subgingival microbiome associated with periodontitis in type 2 diabetes mellitus
Type 2 diabetes mellitus (T2DM) is a systemic disease, predisposing patients to other inflammatory conditions including periodontitis. The...
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Nisin lantibiotic prevents NAFLD liver steatosis and mitochondrial oxidative stress following periodontal disease by abrogating oral, gut and liver dysbiosis
Oral microbiome dysbiosis mediates chronic periodontal disease, gut microbial dysbiosis, and mucosal barrier disfunction that leads to...
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Mechanisms and clinical application potential of mesenchymal stem cells-derived extracellular vesicles in periodontal regeneration
Periodontitis is a high prevalence oral disease which damages both the hard and soft tissue of the periodontium, resulting in tooth mobility and even...
