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1. Elongin B promotes breast cancer progression by ubiquitinating tumor suppressor p14/ARF

   Abstract

   Elongin B (ELOB), a pivotal element in the ELOB/c-Cullin2/5-SOCS-box E3 ubiquitin-protein ligase complex, plays a significant role in...

   **n-Yi Sui, **ao-Yan Ma, ... Wen-Juan Zhang in Cell Biology and Toxicology

   Article Open access 23 April 2024
   

2. Structural Characterization and Functional Studies of Exopolysaccharide by Native Lacticaseibacillus rhamnosus P14 Isolated from the Moroccan Region

   Exopolysaccharides (EPS) are natural polymers synthesized by several microorganisms, including lactic acid bacteria (LAB). They are characterized by...

   Akhtach Sihame, Tabia Zakaria, ... Belkhou Rajae in Current Microbiology

   Article 19 February 2024
   

3. CRL2-KLHDC3 E3 ubiquitin ligase complex suppresses ferroptosis through promoting p14^ARF degradation

   The cystine/glutamate antiporter SLC7A11 (commonly known as xCT) functions to import cystine for glutathione biosynthesis, thereby protecting cells...

   **zhao Zhang, Kun Gao, ... Chenji Wang in Cell Death & Differentiation

   Article 06 November 2021
   

4. Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the  receptor protein of CRL2^Prame complex

   Protein Preferentially Expressed Antigen in Melanoma (Prame), a tumor-associated antigen, has been found to frequently overexpress in various...

   Wenjuan Zhang, Lihui Li, ... Lijun Jia in Cell Death & Differentiation

   Article Open access 27 January 2021
   

5. Farnesoid X receptor functions in cervical cancer via the p14^ARF-mouse double minute 2-p53 pathway

   Background

   Cervical cancer is the second most common cancer among women living in develo** countries. Farnesoid X receptor (FXR) is a member of the...

   **aohua Huang, Bin Wang, ... Ganggang Shi in Molecular Biology Reports

   Article Open access 28 March 2022
   

6. Morphological Peculiarities of Innervation of Rat Epicardial Adipose Tissue in Early Postnatal Ontogenesis

   Abstract

   The study aimed to analyze the structure and innervation of the epicardial adipose tissue (EAT) in the aortic-pulmonary region of the rat...

   E. I. Chumasov, E. S. Petrova, D. E. Korzhevskii in Journal of Evolutionary Biochemistry and Physiology

   Article 01 November 2022
   

7. Structural Organization of GABA- and Nitroxidergic Systems of Subfornical Organ in Wistar Rats Postnatal Development

   Abstract

   The subfornical organ (SFO) is one of the circumventricular organs (CVOs) of the mammalian nervous system responsible for maintaining the...

   V. A. Razenkova, D. E. Korzhevskii in Russian Journal of Developmental Biology

   Article 01 June 2023
   

8. SNAP-25, but not SNAP-23, is essential for photoreceptor development, survival, and function in mice

   SNARE-mediated vesicular transport is thought to play roles in photoreceptor glutamate exocytosis and photopigment delivery. However, the functions...

   Mengjia Huang, Chun Hin Chow, ... Shuzo Sugita in Communications Biology

   Article Open access 05 January 2024
   

9. The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice

   Mutations in GJB2 (Gap junction protein beta 2) are the most common genetic cause of non-syndromic hereditary deafness in humans, especially the...

   Qing Li, Chong Cui, ... Yilai Shu in Cellular and Molecular Life Sciences

   Article Open access 13 May 2023
   

10. Single-cell sequencing reveals the existence of fetal vascular endothelial stem cell-like cells in mouse liver

    Background

    A resident vascular endothelial stem cell (VESC) population expressing CD157 and CD200 has been identified recently in the adult mouse....

    Fitriana N. Rahmawati, Tomohiro Iba, ... Nobuyuki Takakura in Stem Cell Research & Therapy

    Article Open access 30 August 2023
    

11. Dissecting the fate of Foxl2-expressing cells in fetal ovary using lineage tracing and single-cell transcriptomics

    Gonad somatic cells acquire sex-specific fates during sex determination. In XX gonad, a subset of somatic cells expresses Foxl2 after sex...

    **g**g Zhou, **angxiang Jiang, ... Fei Gao in Cell Discovery

    Article Open access 27 December 2022
    

12. Insm1 promotes differentiation of retinal progenitor cells toward photoreceptor cells in the develo** retina through up-regulation of SHH

    This article investigated the effect of Insm1 on RPC differentiation in mice and the underlying mechanism. The retinal tissues of mouse embryo at...

    Pengyi Zhou, Youmei Xu, ... Xuemin ** in Journal of Molecular Histology

    Article 19 October 2022
    

13. Orexin-Immunopositive Structures in the Thalamic Reticular Nucleus

    Abstract

    Orexin-A and orexin-B were immunolocalized in laboratory rodents (adult Wistar and Sprague–Dawley rats, C57Bl/6J mice) in neurons of...

    I. Yu. Morina, I. V. Romanova in Journal of Evolutionary Biochemistry and Physiology

    Article 01 July 2022
    

14. Characterization of the microRNA transcriptomes and proteomics of cochlear tissue-derived small extracellular vesicles from mice of different ages after birth

    The cochlea is an important sensory organ for both balance and sound perception, and the formation of the cochlea is a complex developmental process....

    Pei Jiang, **angyu Ma, ... Renjie Chai in Cellular and Molecular Life Sciences

    Article 26 February 2022
    

15. TMEM30A is essential for hair cell polarity maintenance in postnatal mouse cochlea

    Background

    Phosphatidylserine is translocated to the inner leaflet of the phospholipid bilayer membrane by the flippase function of type IV P-tape...

    Yazhi **ng, Kun Peng, ... Shankai Yin in Cellular & Molecular Biology Letters

    Article Open access 23 March 2023
    

16. Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14^ARF, and TAU3 transcript expression and contribute to cognitive decline

    The accumulation of senescent cells in tissues is causally linked to the development of several age-related diseases; the removal of senescent glial...

    Jed J. Lye, Eva Latorre, ... Lorna W. Harries in GeroScience

    Article Open access 25 October 2019
    

17. Minimal Cube Explant Provides Optimal Isolation Condition of Mesenchymal Stem Cells from Umbilical Cord

    Background:

    Enzymatic digestion and explant method have been widely used for isolating umbilical cord-derived mesenchymal stem cells (UC MSCs),...

    Ah-Young Lee, Kwi-Hoon Jang, Chris Hyunchul Jo in Tissue Engineering and Regenerative Medicine

    Article 24 March 2022
    

18. The Association between Hypermethylation of Gene Promoters and Cytogenetic Disturbances in Humans Exposed to Radiation as a Result of the Chernobyl Accident

    Abstract—

    The estimation of hypermethylation of the cell cycle ( RASSF1A, p16/INK4A, p14/ARF ) and detoxification ( GSTP1 ) gene promoters was carried...

    N. S. Kuzmina, N. Sh. Lapteva, A. V. Rubanovich in Biology Bulletin

    Article 01 December 2021
    

19. CUGBP1, a crucial factor for heart regeneration in mice

    The mammalian heart is capable of achieving perfect regeneration following cardiac injury through sustained cardiomyocyte proliferation during the...

    Yang Liu, Huiwen Wang, ... Guangju Ji in Cell Death & Disease

    Article Open access 08 February 2022
    

20. Proliferation of aneuploid cells induced by CENP-E depletion is counteracted by the p14^ARF tumor suppressor

    The spindle assembly checkpoint (SAC) is a cellular surveillance mechanism that ensures the fidelity of chromosomes segregation. Reduced expression...

    Lorena Veneziano, Viviana Barra, ... Aldo Di Leonardo in Molecular Genetics and Genomics

    Article 27 September 2018