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HPV-associated cervicovaginal microbiome and host metabolome characteristics
BackgroundCervicovaginal microbiome plays an important role in the persistence of HPV infection and subsequent disease development. However,...
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A specific diagnostic metabolome signature in adult IgA vasculitis
IntroductionIgA vasculitis diagnosis relies primarily on clinical features and is confirmed by pathological findings. To date, there is no reliable...
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Blood-brain barrier disruption defines the extracellular metabolome of live human high-grade gliomas
The extracellular microenvironment modulates glioma behaviour. It remains unknown if blood-brain barrier disruption merely reflects or functionally...
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Leaf Endophytes Relationship with Host Metabolome Expression in Tropical Gymnosperms
Plant–microbe interactions play a pivotal role in sha** host fitness, especially concerning chemical defense mechanisms. In cycads, establishing...
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High microbiome and metabolome diversification in coexisting sponges with different bio-ecological traits
Marine Porifera host diverse microbial communities, which influence host metabolism and fitness. However, functional relationships between sponge...
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Noninvasive sampling of the small intestinal chyme for microbiome, metabolome and antimicrobial resistance genes in dogs, a proof of concept
BackgroundThe gastrointestinal microbiome and metabolome vary greatly throughout the different segments of the gastrointestinal tract, however...
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The gut microbiome-metabolome dataset collection: a curated resource for integrative meta-analysis
Integrative analysis of microbiome and metabolome data obtained from human fecal samples is a promising avenue for better understanding the interplay...
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Metabolic-GWAS provides insights into genetic architecture of seed metabolome in buckwheat
BackgroundBuckwheat ( Fagopyrum spp.), belonging to the Polygonaceae family, is an ancient pseudo-cereal with high nutritional and nutraceutical...
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Acute changes in the metabolome following resistance exercise combined with intake of different protein sources (cricket, pea, whey)
IntroductionSeparately, both exercise and protein ingestion have been shown to alter the blood and urine metabolome. This study goes a step further...
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Serum metabolic profile and metabolome genome-wide association study in chicken
BackgroundChickens provide globally important livestock products. Understanding the genetic and molecular mechanisms underpinning chicken economic...
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The plasma metabolome is associated with preservation of physiological function following lifelong aerobic exercise in mice
Declines in physiological function with aging are strongly linked to age-related diseases. Lifelong voluntary aerobic exercise (LVAE) preserves...
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Effects of grain intervention on hypothalamic function and the metabolome of blood and milk in dairy cows
BackgroundThe hypothalamus plays a crucial role in the health and productivity of dairy cows, yet studies on its functionality and its impact on...
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Effects of Heavy Metals on the Metabolome of Pinus sylvestris (Pinaceae)
AbstractThe effects of Cu, Ni, and Cd on the Pinus sylvestris metabolome was studied in experimental conditions by gas chromatography–mass...
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Integrating uterine microbiome and metabolome to advance the understanding of the uterine environment in dairy cows with metritis
BackgroundMetritis is a prevalent uterine disease that affects the welfare, fertility, and survival of dairy cows. The uterine microbiome from cows...
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Fast Sampling of the Cellular Metabolome
Obtaining meaningful snapshots of the metabolome of microorganisms requires rapid sampling and immediate quenching of all metabolic activity, to...
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Scutellaria baicalensis Georgi: Projection of Root Metabolome on Hairy Root Culture
AbstractThe study characterizes flavonoid and phenylethanoid metabolites of Baikal skullcap ( Scutellaria baicalensis ). The roots of intact plants...
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Associations of the placental metabolome with immune maturation up to one year of age in the Swedish NICE-cohort
IntroductionAllergies and other immune-mediated diseases are thought to result from incomplete maturation of the immune system early in life. We...
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Unravelling the seasonal dynamics of the metabolome of white asparagus spears using untargeted metabolomics
IntroductionThe white asparagus season lasts 4 months while the harvest period per field is 8 weeks. Different varieties are better suited for...
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Association between human blood metabolome and the risk of hypertension
Hypertension, commonly referred to as high blood pressure, is a chronic medical condition characterized by persistently elevated blood pressure...
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Transcriptome sequencing and metabolome analysis reveal the metabolic reprogramming of partial hepatectomy and extended hepatectomy
Surgical resection remains a critical treatment option for many patients with primary and secondary hepatic neoplasms. Extended hepatectomy (eHx) may...
