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Understanding LncRNAs in Biomaterials Development for Osteointegration
Osseointegration of implants is a sophisticated healing process comprising of blood clot formation, immune response, angiogenesis, and osteogenesis....
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Validation of the Interaction Between Stress-Responsive LncRNAs and RNA-Binding Proteins In Vitro
Plant long non-coding RNAs (lncRNAs) have been implicated in many biological processes, including responses to abiotic stresses, yet their detailed...
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Super enhancer lncRNAs: a novel hallmark in cancer
Super enhancers (SEs) consist of clusters of enhancers, harboring an unusually high density of transcription factors, mediator coactivators and...
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Integrated analysis of mRNAs and lncRNAs reveals candidate marker genes and potential hub lncRNAs associated with growth regulation of the Pacific Oyster, Crassostrea gigas
BackgroundThe Pacific oyster, Crassostrea gigas , is an economically important shellfish around the world. Great efforts have been made to improve...
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A hidden translatome in tumors—the coding lncRNAs
Long noncoding RNAs (lncRNAs) have been extensively identified in eukaryotic genomes and have been shown to play critical roles in the development of...
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RETRACTED ARTICLE: BCLncRDB: a comprehensive database of LncRNAs associated with breast cancer
Breast cancer, the most common cancer in women, is characterized by high morbidity and mortality worldwide. Recent evidence has shown that long...
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EZH2-interacting lncRNAs contribute to gastric tumorigenesis; a review on the mechanisms of action
Gastric cancer (GC) remains one of the deadliest malignancies worldwide, demanding new targets to improve its diagnosis and treatment. Long...
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Methylated lncRNAs suppress apoptosis of gastric cancer stem cells via the lncRNA–miRNA/protein axis
BackgroundLong noncoding RNAs (lncRNAs) play essential roles in the tumorigenesis of gastric cancer. However, the influence of lncRNA methylation on...
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LncRNAs in Kawasaki disease and Henoch-Schönlein purpura: mechanisms and clinical applications
Kawasaki disease (KD) and Henoch-Schönlein purpura (HSP) are the two most predominant types of childhood vasculitis. In childhood vasculitis, factors...
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Changes of LncRNAs during the Process of Antioxidants Antagonize Cadmium-Induced Oxidative Damage in Islet β Cells
Long non-coding RNAs (LncRNAs) play important regulatory roles in oxidative damage. Resveratrol, curcumin, and cyanidin are phytogenic antioxidants...
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Mitochondria-related lncRNAs: predicting prognosis, tumor microenvironment and treatment response in lung adenocarcinoma
Lung cancer is the most common type of malignant tumor that affects people in China and even across the globe, as it exhibits the highest rates of...
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Interaction between lncRNAs and RNA-binding proteins (RBPs) influences DNA damage response in cancer chemoresistance
The DNA damage response (DDR) is a crucial cellular signaling pathway activated in response to DNA damage, including damage caused by chemotherapy....
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LncRNAs and Cardiovascular Disease
A novel class of RNA molecule emerged from human transcriptome sequencing studies termed long non-coding RNAs. These RNA molecules differ from other...
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Amino acid metabolism regulated by lncRNAs: the propellant behind cancer metabolic reprogramming
Metabolic reprogramming is one of the main characteristics of cancer cells and plays pivotal role in the proliferation and survival of cancer cells....
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Regulatory miRNAs, circRNAs and lncRNAs in cell cycle progression of breast cancer
Breast cancer is a complex and heterogeneous disease that poses a significant public health concern worldwide, and it remains a major challenge...
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Copy number variation-associated lncRNAs may contribute to the etiologies of congenital heart disease
Copy number variations (CNVs) have long been recognized as pathogenic factors for congenital heart disease (CHD). Few CHD associated CNVs could be...
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Comprehensive transcriptomic analysis of three varieties with different brown planthopper-resistance identifies leaf sheath lncRNAs in rice
BackgroundLong non-coding RNAs (lncRNAs) have been brought great attention for their crucial roles in diverse biological processes. However,...
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Integrated analysis of copy number variation-associated lncRNAs identifies candidates contributing to the etiologies of congenital kidney anomalies
Congenital anomalies of the kidney and urinary tract (CAKUT) are disorders resulting from defects in the development of the kidneys and their outflow...
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Identification and analysis of short-term and long-term salt-associated lncRNAs in the leaf of Avicennia marina
As a highly salt-resistant mangrove, Avicennia marina can thrive in the hypersaline water. The leaves of Avicennia marina play a crucial role in...
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Deep Conservation and Unexpected Evolutionary History of Neighboring lncRNAs MALAT1 and NEAT1
Long non-coding RNAs (lncRNAs) have begun to receive overdue attention for their regulatory roles in gene expression and other cellular processes....
