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The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and kidney stones: a cross-sectional study
BackgroundThe relationship between the NHHR and kidney stone risk remains unknown. The purpose of this study was to evaluate the association between...
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Gut microbiota in patients with kidney stones: a systematic review and meta-analysis
BackgroundMounting evidence indicates that the gut microbiome (GMB) plays an essential role in kidney stone (KS) formation. In this study, we...
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Dietary Selenium Intake and Kidney Stones in Old Adults: an Analysis from NHANES 2011 to 2018
The association between dietary selenium intake and kidney stones remains unclear. The purpose of this study was to explore the correlation between...
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Ferroptosis and its emerging role in kidney stone formation
Kidney stone is a common and highly recurrent disease in urology, and its pathogenesis is associated with various factors. However, its precise...
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FKBP5 deficiency attenuates calcium oxalate kidney stone formation by suppressing cell–crystal adhesion, apoptosis and macrophage M1 polarization via inhibition of NF-κB signaling
Surgical crushing of stones alone has not addressed the increasing prevalence of kidney stones. A promising strategy is to tackle the kidney damage...
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StoneNet: An Efficient Lightweight Model Based on Depthwise Separable Convolutions for Kidney Stone Detection from CT Images
Kidney stone disease is one of the most common and serious health problems in much of the world, leading to many hospitalizations with severe pain....
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A cross-sectional analysis of the relationship between the non-high density to high density lipoprotein cholesterol ratio (NHHR) and kidney stone risk in American adults
BackgroundRecent interest in the Non-High Density to High Density Lipoprotein Cholesterol ratio (NHHR) has emerged due to its potential role in...
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Dysregulated palmitic acid metabolism promotes the formation of renal calcium-oxalate stones through ferroptosis induced by polyunsaturated fatty acids/phosphatidic acid
The pathogenesis of renal calcium-oxalate (CaOx) stones is complex and influenced by various metabolic factors. In parallel, palmitic acid (PA) has...
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Lactoferrin and the development of salivary stones: a pilot study
Salivary stones (sialoliths) are calcified structures located in the ductal system of the major salivary glands. Their exact cause is not clear but...
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Effect of Copper and Zinc Ions on Biochemical and Molecular Characteristics of Calcium Oxalate Renal Stones: a Controlled Clinical Study
Contradictory results are existed in the literature regarding the impact of trace elements on the pathogenesis of calcium oxalate (CaOx) stone...
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Two independent modes of kidney stone suppression achieved by AIM/CD5L and KIM-1
The prevalence of kidney stones is increasing and its recurrence rate within the first 5 years is over 50%. No treatments that prevent the...
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The pelvis urinary microbiome in patients with kidney stones and clinical associations
BackgroundThe long-held notion that, without urinary tract or circulatory infection, bladder urine and blood are sterile biofluids has been...
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Chronic Kidney Disease: Challenges in Translational Medicine
Chronic kidney disease (CKD) has long been recognized as a state of progressive decline in renal function. Morbidity and mortality are well...
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The kidney, volume homeostasis and osmoregulation in space: current perspective and knowledge gaps
Although we have sent humans into space for more than 50 years crucial questions regarding kidney physiology, volume regulation and osmoregulation...
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Transformative Deep Neural Network Approaches in Kidney Ultrasound Segmentation: Empirical Validation with an Annotated Dataset
Kidney ultrasound (US) images are primarily employed for diagnosing different renal diseases. Among them, one is renal localization and detection,...
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Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease
Nephrolithiasis is highly prevalent and associated with the increased risk of kidney cancer. The tumor suppressor von Hippel-Lindau (VHL) is critical...
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Genetic variants affecting mitochondrial function provide further insights for kidney disease
BackgroundChronic kidney disease (CKD) is a complex disorder that has become a high prevalence global health problem, with diabetes being its...
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Analysis of stones formed in the human gall bladder and kidney using advanced spectroscopic techniques
Stone diseases (gallstones and kidney stones) are extremely painful and often cause death. The prime aim of biomedical research in this area has been...
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Proteomics and transcriptomics profiling reveals distinct aspects of kidney stone related genes in calculi rats
BackgroundsKidney stone also known as urolithiasis or nephrolithiasis, is one of the oldest diseases known to medicine, however, the gene expression...
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Profiling the urinary microbiome in men with calcium-based kidney stones
BackgroundThe dogma that urine is sterile in healthy individuals has been overturned by recent studies applying molecular-based methods. Mounting...
