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The Complementarity of Nuclear Magnetic Resonance and Native Mass Spectrometry in Probing Protein-Protein Interactions
Nuclear magnetic resonance (NMR) and native mass spectrometry (MS) are mature physicochemical techniques with long histories and important...
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Analyzing Iron and Oxygen-Regulated Protein Complex Formation Using Proteomic Mass Spectrometry
Multicellular organisms have evolved elaborate strategies to sense and adapt to changes in intracellular oxygen. The canonical cellular pathway...
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A pyrenoid-localized protein SAGA1 is necessary for Ca2+-binding protein CAS-dependent expression of nuclear genes encoding inorganic carbon transporters in Chlamydomonas reinhardtii
Microalgae induce a CO 2 -concentrating mechanism (CCM) to maintain photosynthetic affinity for dissolved inorganic carbon (Ci) under CO 2 -limiting...
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Mechanisms of substrate processing during ER-associated protein degradation
Maintaining proteome integrity is essential for long-term viability of all organisms and is overseen by intrinsic quality control mechanisms. The...
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Milk Protein-Based Edible Coatings: Properties and Applications
Dairy industry produces a lot of by-products which when not utilised suitably, get added to the waste. The largest component produced during the...
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Evaluation of crises suitability of food systems: a comparison of alternative protein sources
Global crises affecting food security have kept increasing for four years in a row, with almost 350 million people expected to suffer from food...
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Deubiquitylase OTUD3 prevents Parkinson’s disease through stabilizing iron regulatory protein 2
Iron deposits are neuropathological hallmark of Parkinson’s disease (PD). Iron regulatory protein 2 (IRP2) is a key factor in regulating brain iron...
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Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring
Due to the rise in overnutrition, the incidence of obesity-induced hepatocellular carcinoma (HCC) will continue to escalate; however, our...
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Mono-ADP-ribosylation, a MARylationmultifaced modification of protein, DNA and RNA: characterizations, functions and mechanisms
The functional alterations of proteins and nucleic acids mainly rely on their modifications. ADP-ribosylation is a NAD + -dependent modification of...
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Construction of a constitutively active type III secretion system for heterologous protein secretion
AbstractProteins comprise a multibillion-dollar industry in enzymes and therapeutics, but bacterial protein production can be costly and inefficient....
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Investigation of the Elemental Contents, Functional and Nutraceutical Properties of Kefirs Enriched with Spirulina platensis, an Eco-friendly and Alternative Protein Source
In this study, the effect of the use of S. platensis , which is presented as an eco-friendly and alternative protein source, in the production of...
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Elucidation of the co** strategy in an OMP homozygous knockout mutant of Synechocystis 6803 defective in iron uptake
The TonB-dependent outer membrane (OM) transporters import iron (Fe) under Fe-deficient growth conditions in the unicellular cyanobacterium Synechocystis...
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Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
Immediate restriction of iron initiated by the host is a critical process to protect against bacterial infections and has been described in the liver...
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Targeting apoptosis and unfolded protein response: the impact of β-hydroxybutyrate in clear cell renal cell carcinoma under glucose-deprived conditions
BackgroundClear cell renal cell carcinoma (ccRCC) plays a significant role in the mortality associated with kidney cancer. Targeting biological...
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How is a Zinc Ion Correctly Allocated to a Zinc-dependent Protein?
This book chapter tries to visualize how a bacterial cell manages to bring zinc and no other transition metal cation to a zinc-dependent protein....
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Simultaneous improvement of grain yield and grain protein concentration in durum wheat by using association tests and weighted GBLUP
Key messageSimultaneous improvement for GY and GPC by using GWAS and GBLUP suggested a significant application in durum wheat breeding.
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Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions
An unambiguous description of an experiment, and the subsequent biological observation, is vital for accurate data interpretation. Minimum...
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Dicarbonyl stress, protein glycation and the unfolded protein response
The reactive dicarbonyl metabolite, methylglyoxal (MG), is increased in obesity and diabetes and is implicated in the development of insulin...
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Loss of PPR protein Ppr2 induces ferroptosis-like cell death in Schizosaccharomyces pombe
Ferroptosis is a form of iron- and lipid peroxidation-mediated programmed cell death that occurs widely in mammalian cells. However, this phenomenon...
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Unfolded protein response during cardiovascular disorders: a tilt towards pro-survival and cellular homeostasis
The endoplasmic reticulum (ER) is an organelle that orchestrates the production and proper assembly of an extensive types of secretory and membrane...
