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Exploring antibiotic resistance in environmental integron-cassettes through intI-attC amplicons deep sequencing
IntroductionFreshwater ecosystems provide propitious conditions for the acquisition and spread of antibiotic resistance genes (ARGs), and integrons...
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Characterization and genetic analysis of extensively drug-resistant hospital acquired Pseudomonas aeruginosa isolates
BackgroundThe incidence of hospital-acquired infections in extensively drug-resistant Pseudomonas aeruginosa (XDR-PA) has been increasing worldwide...
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Temporal Dynamics of Antibiotic Resistance Genes in Vegetable Greenhouse Soils Following Different Manure Applications
The profiles of antibiotic resistance genes (ARGs) following manure application in vegetable greenhouse should be paid more attention due to its...
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Influence of class 2 integron integrase concentration on gene cassette insertion and excision in vivo
Integron can capture and express antimicrobial resistance gene cassettes and plays important roles in horizontal gene transfer. The establishment of...
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Environmental impacts of antibiotics addition to algal-bacterial-based aquaponic system
AbstractAntibiotics usage is a double-edged sword among the production promotion and environmental aggravation of aquaculture system. In this study,...
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Mutation of the wheat homeobox gene Grain Number Increase 1 increases grain number and grain yield but decreases grain protein content
Inflorescence structure affects final grain yield (GY) in wheat ( Triticum aestivum L.). Recent breeding efforts have focused on improving grain...
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Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
Integrons are bacterial genetic elements that can capture mobile gene cassettes. They are mostly known for their role in the spread of antibiotic...
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Comparative genomics of trimethoprim-sulfamethoxazole-resistant Achromobacter xylosoxidans clinical isolates from Serbia reveals shortened variant of class 1 integron integrase gene
Trimethoprim-sulfamethoxazole (SXT) is the preferable treatment option of the infections caused by Achromobacter spp. Our study aimed to analyze the...
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Molecular Characteristics and Genetic Analysis of Extensively Drug-Resistant Isolates with different Tn3 Mobile Genetic Elements
Extensively drug-resistant (XDR) bacteria are the main caues for causing clinical infectious diseases. Our aim was to distinguish the present...
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Flaviflexus equikiangi sp. nov. isolated from faeces of Equus kiang (Tibetan wild ass) and carrying a class 1 integron gene cassette in its genome
Two Gram-stain-positive, catalase-negative, non-spore-forming, cocci-shaped strains (dk850 T and JY899) were isolated from the feces of Equus kiang in...
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Prevalence and molecular characterization of colistin resistance in Pseudomonas aeruginosa isolates: insights from a study in Ardabil hospitals
BackgroundPseudomonas aeruginosa is a common cause of nosocomial infections. However, the emergence of multidrug-resistant strains has complicated...
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Comparison of integron mediated antimicrobial resistance in clinical isolates of Escherichia coli from urinary and bacteremic sources
BackgroundAntimicrobial resistance (AMR) is a global threat driven mainly by horizontal gene transfer (HGT) mechanisms through mobile genetic...
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Genotype diversity and antibiotic resistance risk in Aeromonas hydrophila in Sichuan, China
Sichuan is a significant aquaculture province in China, with a total aquaculture output of 1.72 × 10 6 tons in 2022. One of the most significant...
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Antibiotic resistance and carriage class I integron in clinical isolates of Acinetobacter baumannii from Al Muthanna, Iraq
The goal of this work was to systematically characterize and detect class 1, 2, and 3 integrons with many antibiotic resistance A. baumannii strains...
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Molecular Characterization of Integrons and Their Association with Antibiotic Resistance in Acinetobacter baumannii Isolated from Hospitals in Jeddah
AbstractThe drug resistance pattern of infectious A. baumannii isolates of Saudi Arabia was evaluated and the integrons in samples were...
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Tentative Epidemiological Cut-Off Values and Distribution of Resistance Genes in Aquatic Pseudomonas Species Isolated from Rainbow Trout
Epidemiological cut-off value (ECV) analysis for commonly used antimicrobials in aquaculture have not been established for many aquatic pathogens,...
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Screening Key Sites of Class 2 Integron Integrase that Impact Recombination Efficiency
By capturing and expressing exogenous resistance gene cassettes through site-specific recombination, integrons play important roles in the horizontal...
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Antimicrobial susceptibility and genotypic characterization of Escherichia coli isolated from foods controlled by the National Food Safety Agency in Burkina Faso
This study was conducted to determine the antimicrobial resistance profiles of Escherichia coli isolated from food samples received at the National...
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Prevalence and Characterization of Gentamicin Resistance Genes in Escherichia coli Isolates from Beef Cattle Feces in Japan
Gentamicin is an important antibiotic for the treatment of opportunistic infections in the clinical field. Gentamicin-resistant bacteria have been...
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Integron cassettes integrate into bacterial genomes via widespread non-classical attG sites
Integrons are genetic elements involved in bacterial adaptation which capture, shuffle and express genes encoding adaptive functions embedded in...
