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The homeodomain transcription factor CEH-37 regulates PMK-1/p38 MAPK pathway to protect against intestinal infection via the phosphatase VHP-1
Increasing evidence indicate that the expression of defense genes at the right place and the right time are regulated by host-defense transcription...
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In silico and computational analysis of zinc finger motif-associated homeodomain (ZF-HD) family genes in chilli (Capsicum annuum L)
Zinc finger-homeodomain (ZHD) proteins are mostly expressed in plants and are involved in proper growth and development and minimizing biotic and...
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Role of moss and Arabidopsis zinc-finger homeodomain transcription factors in regulating plant architecture
Zinc-finger homeodomain transcription factors (ZF-HD TFs) are relatively a small gene family in Arabidopsis involved in plant development and stress...
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Genome-wide characterization of the TALE homeodomain family and the KNOX-BLH interaction network in tomato
Key messageComprehensive yeast and protoplast two-hybrid analyses illustrated the protein–protein interaction network of the TALE homeodomain protein...
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Genome-wide analysis of zinc finger-homeodomain (ZF-HD) transcription factors in diploid and tetraploid cotton
ZF-HD (zinc finger-homeodomain) gene family plays important roles in plant growth, development, and various stress responses. In the present study,...
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Characterization of a Homeodomain-Leucine Zipper Gene 12: Gene Silencing in Pepper and Arabidopsis-Based Overexpression During Abiotic Stress
Homeodomain-Leucine Zipper (HD-Zip) proteins are important ubiquitous and diverse molecular chaperones in plants. We characterized a gene CaATHB-12 ...
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Comprehensive bioinformation analysis of homeodomain-leucine zipper gene family and expression pattern of HD-Zip I under abiotic stress in Salix suchowensis
BackgroundHomeodomain-leucine zipper (HD-Zip) transcription factors are plant-specific and play important roles in plant defense against...
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Homeodomain Transcription Factors Nkx2.2 and Pax6 as Novel Biomarkers for Meningioma Tumor Treatment
Meningioma is a common brain tumour which has neither a specific detection nor treatment method. The Sonic hedgehog (Shh) cell signaling pathway is a...
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Possible Role of Prep1 Homeodomain Transcription Factor in Cardiac Mesenchymal Stromal Cells
Abstract —Homeodomain transcription factors play a significant role in mesenchymal stromal cells (MSCs). Previously, the role of Meis1, Pbx1 and Prep1...
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Genome-wide identification of the plant homeodomain-finger family in rye and ScPHD5 functions in cold tolerance and flowering time
Key message111 PHD genes were newly identified in rye genome and ScPHD5’s role in regulating cold tolerance and flowering time was suggested.
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Identification and characterization of stress responsive homeodomain leucine zipper transcription factors in Medicago truncatula
BackgroundHomeodomain leucine zipper (HD-ZIP) transcription factors play roles in regulating plant development and responses to abiotic stresses;...
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CcBLH6, a bell-like homeodomain-containing transcription factor, regulates the fruit lignification pattern
Main conclusionCcBLH6 is a bell-like homeodomain-containing transcription factor that plays an important role of lignin biosynthesis in the control...
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The double homeodomain protein DUX4c is associated with regenerating muscle fibers and RNA-binding proteins
BackgroundWe have previously demonstrated that double homeobox 4 centromeric ( DUX4C ) encoded for a functional DUX4c protein upregulated in...
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Functional analysis of enhancer elements regulating the expression of the Drosophila homeodomain transcription factor DRx by gene targeting
BackgroundThe Drosophila brain is an ideal model system to study stem cells, here called neuroblasts, and the generation of neural lineages. Many...
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Structure Analysis of the MatA Locus of Sexual Compatibility in the Edible Mushroom Pleurotus ostreatus
AbstractThe edible oyster mushroom Pleurotus ostreatus is one of the most cultivated species worldwide. Morphogenesis associated with the maturation...
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Response of phytohormone mediated plant homeodomain (PHD) family to abiotic stress in upland cotton (Gossypium hirsutum spp.)
BackgroundThe sequencing and annotations of cotton genomes provide powerful theoretical support to unravel more physiological and functional...
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Irreducible Complexity of Hox Gene: Path to the Canonical Function of the Hox Cluster
AbstractThe evolution of major taxa is often associated with the emergence of new gene families. In all multicellular animals except sponges and comb...
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The homeodomain transcription factor Orthopedia is involved in development of the Drosophila hindgut
BackgroundThe Drosophila hindgut is commonly used model for studying various aspects of organogenesis like primordium establishment, further...
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Genome-wide analysis and expression profiling of the HD-ZIP gene family in kiwifruit
The homeodomain-leucine zipper (HD-Zip) gene family plays a pivotal role in plant development and stress responses. Nevertheless, a comprehensive...
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Revisiting bicoid function: complete inactivation reveals an additional fundamental role in Drosophila egg geometry specification
IntroductionThe bicoid ( bcd ) gene in Drosophila has served as a paradigm for a morphogen in textbooks for decades. Discovered in 1986 as a mutation...
